Product Description
EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Biovision | 3904 | EDEM1 Antibody DataSheet
Antibody Target: EDEM1
Target Alternative Name: ER degradation-enhancing alpha-mannosidase-like protein 1
Tag Line: 100 µg affinity purified rabbit anti-EDEM1 polyclonal antibody.
Category: EDEM1
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat
Immunogen Sequence: Synthetic peptide near the C-terminal of mouse EDEM1
Accession #: Q925U4
Gene ID: 192193
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) antibody in 1 x PBS pH 7.2, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Purification: Affinity purified
Application: Western blot
Positive Control: Rat Kidney tissue lysate
Application And Usages: Western blot: (1:200 dilution) Use 0.5 4 µg/ml based on your sample type.
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified