Product Description
Biovision | E4797 | Alpha Crosslaps (αCTx) (Human) ELISA Kit DataSheet
CrossLaps (CTx) peptide [Glu-Lys-Ala-His-Asp-Gly-Gly-Arg], a part of the C-telopeptide of the alpha 1-chain of type I collagen of bone, is developed as a biochemical marker of bone turnover. The Alpha CrossLaps is intended for use as an indicator of degradation of non-isomerized bone collagen and may be used as an aid in the identification of skeletal metastases in patients with breast and prostate cancer. BioVisions Alpha Crosslaps (αCTx) (Human) ELISA Kit is based on Competitive ELISA principle. The micro-plate provided in this kit has been pre-coated with αCTx. During the reaction, αCTx in the samples or standard competes with αCTx coated on the plate for binding to the anti- αCTx antibody. Then Horseradish Peroxidase (HRP) conjugate is added to each micro plate well, and TMB substrate is for color development. There is a negative correlation between the OD value of samples and the concentration of αCTx. The concentration of αCTx in the samples can be calculated by comparing the OD of the samples to the standard curve.
Alternate Name : a-CTXI, aCTX-I, A-Cr, Type I Collagen C-Telopeptide-Related Fraction
Tag Line : A Competitive ELISA kit for in vitro quantitative determination of α-CrossLaps concentrations in serum, plasma and other biological fluids.
Summary :
Detection Method : Absorbance (450 nm)
Sample Type : Plasma, Serum, Other biological fluids
Species Reactivity : Human
Applications : A Competitive ELISA kit for in vitro quantitative determination of α-CrossLaps concentrations in serum, plasma and other biological fluids.
Features and Benefits : Detection Range: 93.75-6000 pg/mL, Specificity: No Significant cross-reactivity or interference between Human α-CTx and analogues was observed., Sensitivity: 56.25 pg/mL, Precision:Coefficient of variation is < 10%.