Biovision | Human Recombinant Proteins

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Biovision | IGF-BP4, human recombinant | 7166

IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the...

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Biovision | IGF-BP3, human recombinant | 4720

Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of...

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Biovision | IGF-BP2, human recombinant | 7165

IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein...

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Biovision | IFN-, human recombinant | 7164

IFN- is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-, IFN-, and IFN-, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative...

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Biovision | IFN-2, human recombinant | 7163

IFN -1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-R1 subunit (also called CRF2-12) and IL-10R2...

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Biovision | IFN-1, human recombinant | 7162

IFN -1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-R1 subunit (also called CRF2-12) and IL-10R2...

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Biovision | IFN-gamma, human recombinant | 4116

IFN- is a lymphoid factor that possesses potent anti-viral activity. It has also been shown that INF-g stimulates microphages and NK cells. Recombinant human IFN- is a 16.9 kDa protein containing 144 amino acid residues.Biovision | 4116 | IFN-gamma human...

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Biovision | IFN-beta 1b, human recombinant | 4860

Recombinant Human IFN- 1b produced from E.Coli is a single, non-glycosylated human Interferon- 1b polypeptide chain containing 165 amino acids and having a molecular mass of 18.51 kDa. The Interferon- 1b gene was cloned from human fibroblasts. IFN- 1b is...

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Biovision | IFN-alpha 2b, human recombinant | 4595

IFN- 2b is a lymphoid factor that possesses potent anti-viral activity. Human IFN- 2b is a 19.3 kDa protein containing 165 amino acid residues.Biovision | 4595 | IFN-alpha 2b human recombinant DataSheetBiomolecule/Target: IFN-alpha 2bSynonyms: Interferon...

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Biovision | IFN-alpha 2a, human recombinant | 4594

Recombinant human IFN- 2a is a single, non-glycosylated, polypeptide chain with a molecular mass 19.4 kDa containing 166 amino acid residues.Biovision | 4594 | IFN-alpha 2a human recombinant DataSheetBiomolecule/Target: IFN-alpha 2aSynonyms: Leukocyte...

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Biovision | IFN-alpha 1, human recombinant | 4596

IFN-1 is a lymphoid factor that possesses potent anti-viral activity. Human IFN- is a 19.3 kDa protein containing 166 amino acid residues.Biovision | 4596 | IFN-alpha 1 human recombinant DataSheetBiomolecule/Target: IFN-alpha 1Synonyms: IFN- 1,...

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Biovision | IDO1, human recombinant | P1096

IDO1 is an indoleamine 2,3-dioxygenase - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, and serotonin. It is...

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Biovision | ICAM-1, human recombinant | 7161

ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to...

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Biovision | I-309, human recombinant | 4113

Human I-309 is a small glycoprotein secreted by activated T lymphocytes. It is structurally related to other CC chemokines. The recombinant human I-309 is an 8.5 kDa protein containing 74 amino acid residues.Biovision | 4113 | I-309 human recombinant...

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Biovision | Human Thyroglobulin | P1025

Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of...

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Biovision | Human Stathmin 1 / STMN1 Protein | 7881

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as...

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Biovision | Human Recombinant Ubiquitin-K6R | 6499

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K63 | 6497

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K6 | 6395

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K48 | 6400

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K33 | 6399

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K29 | 6398

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K27R | 6405

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K27 | 6397

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K11R | 6404

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K11 | 6396

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Ubiquitin-K0 | 6498

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this...

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Biovision | Human Recombinant Alpha-Enolase | 6363

Alpha-enolase, also known as Enolase 1, is one of three enolase isoenzymes and a glycolytic enzyme expressed in most tissues. This protein plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen...

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Biovision | Human Recombinant AKR1C3 | 6337

Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important...

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Biovision | Human Inosine-5-Monophosphate Dehydrogenase II, human recombinant | P1131

Inosine monophosphate dehydrogenase, IMPDH, (E.C. 1.1.1.205) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis and it is essential for lymphocyte proliferation. IMPDH oxidizes inosine 5-monophosphate (IMP) to xanthine...

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Biovision | Human Ghrelin | 4990

Ghrelin (ghre is the Proto-Indo-European root of the word grow) has been identified as the endogenous ligand for the GHS-R (growth hormone secretagogues receptor). Ghrelin is expressed in the stomach, small and large intestines, and brain regions...

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Biovision | Human CellExp KLF4-TAT, Human Recombinant | P1011

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during...

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Biovision | Lin28-TAT, Human Recombinant | P1010

Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA...

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Biovision | HPRT1, human recombinant | P1092

Hypoxanthine-guanine phosphoribosyltransferase, also known as HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. The enzyme primarily functions to salvage purines from degraded DNA to renewed purine...

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Biovision | HMG-CoA Reductase Catalytic Domain (GST Tagged), human recombinant | 7841

HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGR) (EC 1.1.1.34) is a transmembrane protein involved in the mevalonate pathway, the metabolic pathway that produces cholesterol from acetyl-CoA. In an NADPH-dependent reaction, HMG-CoA...

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Biovision | Histone H4 (1-103 aa), Human recombinant | 7671

H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility...

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Biovision | Histone H3 (1-136 aa), Human recombinant | 7670

H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility...

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Biovision | HGF, human recombinant | 4509

Human Hepatocyte Growth Factor (HGF) is also known as Scatter Factor and Hepatopoeitin A. HGF is a potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. Recombinant human HGF is...

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Biovision | Heregulin-2 (HRG2), Human Recombinant | 4730

Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene...

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Biovision | HER2, Active, Human Recombinant | 8011

HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular...

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Biovision | Heat Shock Protein 90 (Hsp90), human recombinant | 4858

Hsp90 is a molecular chaperone and is one of the most abundant proteins in unstressed cells. In mammalian cells, there are two genes encoding cytosolic Hsp90 homologues, with the human Hsp90 showing 85% sequence identity to Hsp90. The recombinant Hsp90...

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Biovision | Heat Shock Protein 90 (Hsp90 beta) NT-His Tag, human recombinant | 4858H

Hsp90 is a molecular chaperone and is one of the most abundant proteins in unstressed cells. In mammalian cells, there are two genes encoding cytosolic Hsp90 homologues, with the human Hsp90 showing 85% sequence identity to Hsp90. The recombinant Hsp90...

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Biovision | Heat Shock Protein 70, human recombinant | 4859

HSP70 and HSP90 are molecular chaperones expressed constitutively under normal conditions to maintain protein homeostasis and are induced upon environmental stress. Both HSP70 and HSP90 are able to interact with unfolded proteins to prevent irreversible...

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Biovision | Heat Shock Protein 27, human recombinant | 4853

Recombinant Human Heat Shock Protein produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids and have a molecular weight of 22.7 kDa. The protein was purified by proprietary chromatographic techniques.Biovision |...

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Biovision | HDAC-8, human recombinant | 7618

Human Histone Deacetylase 8 (HDAC8) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the...

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Biovision | HDAC-3, Human Recombinant | 7613

Human Histone Deacetylase 3 (HDAC3) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the...

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Biovision | HCC-1, human recombinant | 4110

Human HerpatoCellular Carcinoma (HCC-1) was first isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a 46% amino acid sequence identity with MIP-1 /MIP-1 and 29%-37% homology with other CC chemokines. The human HCC-1 is an...

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Biovision | HB-EGF, human recombinant | 4266

HB-EGF is an EGF related growth factor which signals via the EGF receptor, and stimulates the proliferation of SMC (smooth muscle cells), fibroblasts, epithelial cells and keratinocytes. HB-EGF is expressed in various cell types and tissues, including...

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Biovision | GSK-3, human recombinant | 7004

Glycogen synthase kinase-3 (GSK-3) is a serine/theronine kinase that was first characterized by its role in intermediary metabolism. In mammals, serine kinase is encoded by two related genes called GSK-3 (51 kDa) and GSK-3 (46 kDa). GSK-3 has been...

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Biovision | Growth Hormone, human recombinant | 4769

Recombinant Human Pituitary Growth Hormone produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 22367 Dalton. Pituitary Growth Hormone is purified by proprietary chromatographic...

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Biovision | GRO-gamma, human recombinant | 4107

Human GRO- is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. Recombinant human GRO- is a 7.9 kDa protein containing 73 amino acid residues.Biovision | 4107 | GRO-gamma human recombinant...

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Biovision | GRO-beta, human recombinant | 4106

Human GRO- is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GRO- like GRO- specifically inhibits growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent...

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