Product Description
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. Recombinant human ITGB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Biovision | P1581 | Integrin beta 1, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, CD29
Alternates names: Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, CD29
Taglines: Membrane receptor involved in cell adhesion
NCBI Gene ID #: 3688
NCBI Gene Symbol: ITGB1
Gene Source: Human
Accession #: P05556
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGE: >80%
Assay: SDS - PAGE
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 51.7 kDa (462aa) (N terminus His-tag)
Concentration:
Appearance: Liquid protein
Physical form description: In 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
Reconstitution Instructions:
Amino acid sequence: aa 21-465
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans