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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Calpain Inhibitor I, ALLN

    Biovision | Calpain Inhibitor I, ALLN | 1834

    A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki = 6 µM). Can initiate apoptosis in HL-60 cells but...

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  • Calcein AM

    Biovision | Calcein AM | 1755

    A cell-permeable, non-fluorescent acetoxymethyl ester derivative of Calcein that gets hydrolyzed inside the cell by esterases. The loss of the acetoxymethyl group also enables calcein to readily bind intracellular calcium resulting in a strong...

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  • CAL-101 (GS-1101)

    Biovision | CAL-101 (GS-1101) | 2613

    CAL-101 is a cell-permeable inhibitor of the PI3K catalytic subunit p110δ (IC₅₀ = 2.5 nM) that displays 40- to 300-fold selectivity against other PI3K class I enzymes (IC₅₀s = 820, 565, and 89 nM for p110α, β, and γ, respectively). It has also been shown...

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  • C7280948

    Biovision | C7280948 | B1153

    C7280948 is an inhibitor of PRMT1 (Protein arginine N-methyltransferase 1) with IC₅₀ value of 12.75 μM. It serves as a useful tool in studying the role of PRMT1 in epigenetics. PMRT1 has been reported to activate estrogen and androgen receptors and is an...

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  • C2-Dihydroceramide

    Biovision | C2-Dihydroceramide | 2391

    A useful negative control for C2 Ceramide (Cat. No. 2390-5, 25). Also acts as an autophagy inducer.C2-dihydroceramide is a useful negative control for C2 Ceramide (Cat. No. 2390-5, 25). Also acts as an autophagy inducer.Biovision | 2391 |...

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  • C2 Ceramide

    Biovision | C2 Ceramide | 2390

    A cell-permeable ceramide analog. Induces apoptosis in a variety of cell types. Stimulates ceramide-activated protein phosphatases and activates ceramide-activated protein kinases.C2 ceramide is a cell-permeable ceramide analog. Induces apoptosis in a...

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  • C K-666

    Biovision | C K-666 | B2147

    CK-666 is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC₅₀ = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the...

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  • BX-517

    Biovision | BX-517 | B1764

    BX-517, also known as PDK1 inhibitor2, is a potent and selective PDK1 inhibitor that binds to the ATP binding pocket.BX-517, also known as PDK1 inhibitor2, is a potent and selective PDK1 inhibitor that binds to the ATP binding pocket.Biovision | B1764 |...

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  • BX-471

    Biovision | BX-471 | B2407

    BX-471 is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM; displays 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.BX-471 is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM; displays 250-fold selectivity...

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  • BTK Inhibitor, PCI-32765

    Biovision | BTK Inhibitor, PCI-32765 | 2298

    A potent and highly selective small-molecule inhibitor of Bruton's tyrosine kinase (BTK) (IC₅₀ = 0.5 nM) with potential antineoplastic activity. It.binds to and irreversibly inhibits BTK activity, thereby preventing both B-cell activation and...

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  • BTK Inhibitor, CNX-774

    Biovision | BTK Inhibitor, CNX-774 | 2600

    CNX-774 is a potent, irreversible BTK inhibitor (IC₅₀ < 1 nM). CNX-774 is highly selective for BTK, and forms a ligand-directed covalent bond with the Cys-481 residue within the ATP binding site of the enzyme.CNX-774 is a potent, irreversible BTK...

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  • BS3 Crosslinker

    Biovision | BS3 Crosslinker | 2327

    KEY FEATURES: • Amine-reactive; has a non-cleavable spacer with arm length of 11.4 Å • Water-soluble • Membrane-impermeable APPLICATIONS: • Crosslinking of proteins through reaction with primary amines • Useful for cross-linking cell surface...

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  • BS-181 dihydrochloride

    Biovision | BS-181 dihydrochloride | B2180

    BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC₅₀ = 21 nM). It displays >40-fold selectivity for CDK7 over others CDKs. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft...

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  • Bryostatin 1

    Biovision | Bryostatin 1 | 2513

    Bryostatin 1 is a naturally occurring macrocyclic lactone that binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. More potent than phorbol myristate acetate for...

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  • Bromodomain Inhibitor, (+)-JQ1

    Biovision | Bromodomain Inhibitor, (+)-JQ1 | 2070

    Cell-permeable. A potent and highly specific inhibitor for the BET (bromodomain and extra-terminal) family of bromodomains. (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively. The binding is competitive with acetyl...

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  • Bromocryptine (mesylate)

    Biovision | Bromocryptine (mesylate) | 2916

    Bromocriptine is a potent Cytochrome P450 3A inhibitor (~770 nM, see cat#K702). It also acts as a dopamine receptor agonist via the D2 receptor (Ki = 2.5 nM). As a result, it is used in combination therapy for Parkinsons disease. It also binds to the...

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  • BRL15572 hydrochloride

    Biovision | BRL15572 hydrochloride | B2179

    BRL-15572 hydrochloride is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B. It displays little or no affinity for a range of other receptor types.BRL-15572 hydrochloride is a selective h5-HT1D antagonist, displaying 60-fold...

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  • Brigatinib analog

    Biovision | Brigatinib analog | B2025

    Brigantinib alalog is an analog of Brigatinib (AP26113) (Cat.No. 9675), a phosphine oxide-containing ALK inhibitor. It potently inhibits ALK (IC₅₀ = 0.07 nM) over IGF-1R and InsR (IC₅₀s = 3.2 and 100 nM, respectively. Brigantinib alalog is an analog of...

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  • Brigatinib (AP26113)

    Biovision | Brigatinib (AP26113) | 9675

    Brigatinib is a highly potent and selective ALK (anaplastic lymphoma kinase) inhibitor. Potentially useful for the treatment of non-small cell lung cancer (NSCLC).Brigatinib is a highly potent and selective ALK (anaplastic lymphoma kinase) inhibitor...

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  • BRD-7552

    Biovision | BRD-7552 | B2258

    BRD-7552 is an inducer of pancreatic and duodenal homeobox 1 (PDX1), a transcription factor involved in pancreas development and function. BRD-7552 dose-dependently increases PDX1 and insulin gene expression, as well as PDX1 protein levels, in PANC-1...

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  • BRD-73954

    Biovision | BRD-73954 | 9596

    BRD-73954 ia a potent and selective HDAC inhibitor with IC₅₀ of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.BRD-73954 ia a potent and selective HDAC inhibitor with IC₅₀ of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.Biovision | 9596 |...

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  • BQ-788 Sodium Salt

    Biovision | BQ-788 Sodium Salt | B1554

    BQ-788 is a potent and selective antagonist of endothelin (ET) B-receptor (IC₅₀ = 1.2 nM). BQ-788 is a good tool for demonstrating the role of ET-1 and ET(B) receptor subtypes in physiological and/or pathophysiological conditions. Q-788 competitively...

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  • BQ-610

    Biovision | BQ-610 | B1553

    BQ-610 is a highly potent and selective ETAR (ETA receptor) antagonist (IC₅₀ = 20 nM) that ttenuates ET-induced reduction in cardiac output. It also inhibits ET-1- and ET-3-induced activation of adenylate cyclase (IC₅₀ = 28.2 nM). BQ-610 is 30-fold more...

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  • BQ-123 Sodium Salt

    Biovision | BQ-123 Sodium Salt | B1552

    BQ-123 sodium is a potent and selective ETA endothelin receptor antagonist (Ki values are 1.4 and 1500 nM at ETA and ETB receptors respectively). It also inhibits ET-1 receptor binding and blocks Ca²⁺ mobilization, cellular contraction and MAP kinase...

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  • Bosutinib (SKI-606)

    Biovision | Bosutinib (SKI-606) | 1584

    Bosutinib (SKI-606) is a novel tyrosine kinase inhibitor. Bosutinib can overcome not only Bcr-Abl-dependent mechanisms of resistance, but also those that are Bcr-Abl-independent. It is used to treat patients with chronic myelogenous leukemia (CML) who...

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  • Bostrycin

    Biovision | Bostrycin | B2128

    Bostrycin is a tetrahydroanthraquinone isolated from Bostrychonema aloestre. It induces mitochondria-mediated apoptosis in the yeast saccharomyces cerevisiae, inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt...

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  • Borrelidin

    Biovision | Borrelidin | 2367

    A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC₅₀ = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the...

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  • Bohemine

    Biovision | Bohemine | B1040

    Bohemine is a potent and selective, cell-permeable, cyclin-dependent kinase (CDK) inhibitor IC₅₀ = 1 µM). Arrests cell cycle in the G/S boundary and activates mature bovine oocytes. Bohemine is structurally similar to Olomoucine and Roscovitine (Cat. No...

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  • BODIPY-Cyclopamine

    Biovision | BODIPY-Cyclopamine | 2160

    A fluorescent Cyclopamine (Cat. No. 1578-5) derivative that retains potency in Shh signaling inhibition (IC₅₀ = 150 nM).BODIPY-Cyclopamine is a fluorescent Cyclopamine (Cat. No. 1578-5) derivative that retains potency in Shh signaling inhibition (IC₅₀ =...

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  • BODIPY-Acetylene Reagent

    Biovision | BODIPY-Acetylene Reagent | 2594

    BODIPY-acetylene is a useful reagent to prepare BODIPY-linked conjugates of lipids, fatty acids, triglycerides, etc. employing click chemistry.BODIPY-acetylene is a useful reagent to prepare BODIPY-linked conjugates of lipids, fatty acids, triglycerides,...

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  • BN-82002

    Biovision | BN-82002 | B2371

    BN-82002 is a cell-permeable CDC25 Phosphatase Inhibitor. BN-82002 is a potent, cell-permeable, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively)...

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  • BMS-986205

    Biovision | BMS-986205 | B1839

    BMS-986205 is a potent and selective IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor. Does not have much effect on IDO2 (indoleamine 2,3-dioxygenase 2) or TDO (Tryptophan 2,3-dioxygenase).BMS-986205 is a potent and selective IDO1 (indoleamine...

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  • BMS-863233 hydrochloride

    Biovision | BMS-863233 hydrochloride | 2598

    BMS-863233 is a potent and selective CDC7 (cell division cycle 7 homolog) inhibitor. BMS-863233 binds to and inhibits the activity of CDC7, resulting in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the...

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  • BMS-777607

    Biovision | BMS-777607 | 2455

    A potent, selective and ATP-competitive Met kinase superfamily inhibitor (IC₅₀ = 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM for c-Met, Axl, RON, and Tyro-3, respectively). it was >40-fold selective for Met kinase family targets versus Lck, VEGFR-2, and TrkA/B and...

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  • BMS-708163

    Biovision | BMS-708163 | B1622

    BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectivelyBMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectivelyBiovision | B1622...

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  • BMS-663068

    Biovision | BMS-663068 | B2299

    BMS-663068 (Fostemsavir) is a potent HIV-1 attachment inhibitor. Fostemsavir is a prodrug of the small-molecule inhibitor BMS-626529 (Cat. No. B1557) which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering...

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  • BMS-626529

    Biovision | BMS-626529 | B1557

    BMS-626529 is a potent attachment inhibitor of HIV-1 gp120 with IC₅₀ values of 2.26 nM, 0.34 nM and 1.3 nM for HIV-1 subtype A, B, and C envelope, respectively.BMS-626529 is a potent attachment inhibitor of HIV-1 gp120 with IC₅₀ values of 2.26 nM, 0.34...

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  • BMS-582949

    Biovision | BMS-582949 | B1704

    BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor.BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor.Biovision | B1704 | BMS-582949 DataSheetAlternate Name/Synonyms:...

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  • BMS-345541 (Free base)

    Biovision | BMS-345541 (Free base) | B1907

    BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC₅₀ value of 4 μM and 0.3 μM, respectively. It binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice. Cell-permeable.BMS-345541 is a highly...

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  • BMS-299897

    Biovision | BMS-299897 | 9606

    BMS-299897 is a potent, brain-permeant γ-secretase inhibitor (IC₅₀ = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC₅₀ values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Displays no Notch...

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  • BMN-673

    Biovision | BMN-673 | B1861

    BMN-673 is a potent and selective PARP1/2 inhibitor with Ki values of 1.2 and 0.9 nM, respectively. It had no effect on panels of 72 receptors, ion channels, and enzymes. BMN-673 displays selective antitumor cytotoxicity and elicits DNA repair biomarkers...

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  • BML210

    Biovision | BML210 | B1128

    BML-210 (also known as CAY10433), is a histone deacetylase (HDAC) inhibitor. BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells.BML-210 (also known as CAY10433), is a histone...

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  • BLU-554

    Biovision | BLU-554 | B2359

    BLU-554 is a potent inhibitor of recombinant fibroblast growth factor receptor 4 (FGFR4) IC₅₀ < 10 nM). It also inhibits phosphorylation of ERK (IC₅₀ < 10 nM), a marker of FGFR4 inhibition, in MDA-MB-453 breast cancer cells.BLU-554 is a potent inhibitor...

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  • Bleomycin sulfate

    Biovision | Bleomycin sulfate | 2246

    An antitumor antibiotic isolated from Streptomyces verticillus. Radiomimetic DNA-cleaving agent that produces double and single DNA strand breaks through an oxygen-radical-dependent mechanism. Inhibits intracellular DNA replication. DNA alkylating agent...

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  • BIX 01294

    Biovision | BIX 01294 | 1678

    Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.BIX01294 selectively impairs the G9a...

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  • bisBenzimide H 33342

    Biovision | bisBenzimide H 33342 | 2179

    A cell-permeable fluorescent DNA stain with low cytotoxicity that binds preferentially to adenine-thymine (A-T) regions of DNA. This stain binds into the minor groove of DNA and exhibits distinct fluorescence emission spectra that are dependent on...

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  • bisBenzimide H 33258

    Biovision | bisBenzimide H 33258 | 2178

    A fluorescent DNA stain with low cytotoxicity that binds preferentially to adenine-thymine (A-T) regions of DNA. Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry.bisBenzimide H 33258 is a a...

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  • Biotinyl-ASTD-FMK

    Biovision | Biotinyl-ASTD-FMK | 1985

    A biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII, which is a proinflammatory cytokine and a chemoattractant...

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  • Biotinyl Tyramide

    Biovision | Biotinyl Tyramide | B2149

    Biotinyl tyramide is a reagent for use in catalyzed reporter deposition (CARD) signal amplification protocols in a variety of immunoassays in which, horseradish peroxidase catalyzed deposition of biotinyl tyramide is detected with labeled streptavidin...

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