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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Aftin-5

    Biovision | Aftin-5 | 2575

    Roscovitine-related purine with no activity on CDKS. Selectively and potently increases production of extracellular Aβ42 and decreases production of extracellular Aβ38 in cultured cells...

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  • AF353

    Biovision | AF353 | B2318

    A potent P2X3/P2X2/3 receptor antagonist; inhibits human and rat P2X3 (pIC₅₀ = 8.0).AF-353 is a potent P2X3/P2X2/3 receptor antagonist; inhibits human and rat P2X3 (pIC₅₀ = 8.0).Biovision | B2318 |...

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  • AEE-788

    Biovision | AEE-788 | 9658

    AEE-788 is a potent EGFR and VEGFR inhibitor (IC₅₀ values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively). Also inhibits c-Abl, c-Fms and c-Src...

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  • AEBSF.HCl

    Biovision | AEBSF.HCl | 1644

    A specific, irreversible serine protease inhibitor. Inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin and trypsin. A stable, non-toxic and better soluble alternative to PMSF.AEBSF...

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  • ADW-742

    Biovision | ADW-742 | B2197

    ADW-742 is an ATP-competitive inhibitor of IGF1R (IC₅₀ in the range of 0.1-0.2 μM) with potential anticancer activity. It synergistically enhances the sensitivity of SCLC (small cell lung cancer) to...

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  • ACY-1215

    Biovision | ACY-1215 | 2629

    ACY-1215 is a potent, cell-permeable and selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5 nM). ACY-1215 is 12-, 10-, 11 and 21-fold less active against HDAC1, HDAC2, HDAC3 and HDAC8,...

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  • Ac-WEHD-pNA

    Biovision | Ac-WEHD-pNA | B2282

    Ac-WEHD-pNA is a useful colorimetric substrate for group I caspases (caspase-1, -4, and -5). Cleavage of the substrate by a caspase releases pNA, which can be detected by its absorbance at 405 nm...

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  • Ac-WEHD-AFC

    Biovision | Ac-WEHD-AFC | B2214

    Ac-WEHD-AFC is a useful fluorogenic substrate for group I caspases (caspase-1, -4, and -5). Caspase activity can be quantified by fluorescent detection of free AFC that has an excitation maximum at...

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  • Ac-VEID-pNA

    Biovision | Ac-VEID-pNA | B2283

    Ac-VEID-pNA, is a colorimetric substrate for caspase-6 and related cysteine proteases. Cleavage of the substrate by a caspase results in the release of pNA, which can be detected by its absorbance at...

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  • ACT-129968

    Biovision | ACT-129968 | B2316

    A potent and selective CRTh2 antagonist. CRTh2 is a G-protein-coupled receptor for prostaglandin D2 (PGD2), a key mediator in inflammatory disorders.ACT-129968 is a potent and selective CRTh2...

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  • Aconitine

    Biovision | Aconitine | 2423

    Aconitine is diterpene alkaloid derived from the tubers of aconitinum plants. It is a neurotoxin that opens TTX(tetrodotoxin)-sensitive Na⁺ channels in the heart and other tissues, and is used for...

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  • Acivicin

    Biovision | Acivicin | B1028

    Acivicin is an antibiotic that inhibits γ-glutamyl transpeptidase (γ-GT), an enzyme involved in transferring g-glutamyl groups in the cell membranes of kidneys, heart, brain, and pancreas. Acivicin...

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  • ACC2 Inhibitor

    Biovision | ACC2 Inhibitor | 1717

    Cell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC₅₀ = 28 nM for hACC2 vs 210 nM for hACC1 in in vitro studies).ACC2 inhibitor is a potent and selective inhibitor...

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  • ABT-888

    Biovision | ABT-888 | 1620

    Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and...

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  • ABT-869

    Biovision | ABT-869 | 1615

    ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC₅₀ value of 4 nM), but has much less activity (IC₅₀ values >1 µM) against unrelated receptor...

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  • ABT751

    Biovision | ABT751 | 2836

    ABT751 is a potent inhibitor of microtubule polymerization. It binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell...

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  • ABT-494

    Biovision | ABT-494 | B1947

    ABT-494 is a potent and selective Janus kinase JAK-1 inhibitor (IC₅₀ = 43 nM). ABT-494 is 74-fold more selective for JAK-1 over JAK-2 and 58-fold more selective for JAK-1 over JAK-3.ABT-494 is a...

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  • ABT-263

    Biovision | ABT-263 | 2467

    A potent, small molecule Bcl-2 family protein inhibitor (Ki’s of <1 nmol/L for Bcl-2, Bcl-XL and Bcl-w). Displays anticancer properties. Selectively binds to apoptosis suppressor proteins Bcl-2,...

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  • ABL-001

    Biovision | ABL-001 | B1949

    ABL-001 is a potent allosteric inhibitor of BCR-ABL. ABL001 binds to the myristoyl pocket of ABL1 and induces the formation of an inactive kinase conformation. ABL001 prevents emergence of resistant...

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  • ABC294640

    Biovision | ABC294640 | B1231

    ABC294640 is a specific spingosine kinase-2 (SK-2) inhibitor having antineoplastic activity. This orally available aryl admantane molecule upon administration binds and inhibits SK-2, preventing...

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  • ABC-1183

    Biovision | ABC-1183 | B2221

    ABC-1183 is a potent and selective dual GSK3α/β and CDK9 inhibitor.ABC-1183 is a potent and selective dual GSK3α/β and CDK9 inhibitor.Biovision | B2221 | ABC-1183 DataSheetAlternate Name/Synonyms:...

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  • Abametapir

    Biovision | Abametapir | 9665

    Abametapir is a metalloprotease inhibitor potentially useful for the treatment of head lice infestation. It is the active ingredient of Xeglyze Lotion.Abametapir is a metalloprotease inhibitor...

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  • AAL-993

    Biovision | AAL-993 | 2740

    AAL-993 is a potent, selective and cell-permeable inhibitor of VEGFR-1 (IC₅₀ = 130 nM), VEGFR-2 (IC₅₀ = 23 nM) and VEGFR-3 (IC₅₀ = 18nM). At higher concentrations it inhibits PDGFR (640 nM), c-Kit...

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  • A77 1726

    Biovision | A77 1726 | 1973

    Physiologically active metabolite of the immunosuppressive drug leflunomide (Cat. No.1972-10, 50). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks...

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  • A37

    Biovision | A37 | B1577

    A37 is a aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC₅₀ = 4.6 μM; Ki = 300 nM). Displays selectivity for ALDH1A1 over eight other ALDH isoforms. A37 disrupts OC spheroid formation and cell...

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  • 8-Br-cGMP

    Biovision | 8-Br-cGMP | 1838

    A cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase (PKG), slows or inhibits the intracellular calcium...

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  • 8-Br-cAMP

    Biovision | 8-Br-cAMP | 1837

    A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and...

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  • 7-Nitroindazole

    Biovision | 7-Nitroindazole | 2360

    A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively...

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  • 7BIO

    Biovision | 7BIO | 9690

    7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase)...

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  • 6-Gingerol

    Biovision | 6-Gingerol | 2507

    Bioactive compound found in ginger (Zingiber officinale). Displays antioxidant, anti-inflammatory and antitumor properties. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages...

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  • 6-Azauridine

    Biovision | 6-Azauridine | B1024

    6-Azauridine is a synthetic triazine analog of uridine with antimetabolite activity. 6-Azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono,...

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  • 680C91

    Biovision | 680C91 | 2292

    Cell-permeable. A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO, Ki = 51 nM.) Tryptophan is metabolized to the endogenous AHR ligand by TDO which may be inhibited by 680C91...

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  • 4SC-202

    Biovision | 4SC-202 | B1230

    4SC-202 is an orally available potent HDAC inhibitor (HDACi) specific for class I HDAC isoenzymes with IC50s of 1.2/1.12/0.57 µM for HDAC1/2/3; displays high selectivity over ClassIIa/IIb/III HDACs...

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  • 4-Hydroxynonenal

    Biovision | 4-Hydroxynonenal | 2083

    4-hydroxynonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits...

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  • 4'-Hydroxychalcone

    Biovision | 4'-Hydroxychalcone | B1921

    4'-Hydroxy chalcone is a chalcone metabolite with diverse biological activities. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner. Also known to activate...

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