Euro
USD
British Pound
NULL
Product Description
Benazepril is a prodrug of the angiotensin converting enzyme (ACE) inhibitor benazeprilat. It is metabolized to benazeprilat by hepatic esterases. Benazepril inhibits the in vitro enzymatic activity of partially purified ACE isolated from rabbit lung (IC₅₀ = 2 nM). Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.
Benazepril is a prodrug of the angiotensin converting enzyme (ACE) inhibitor benazeprilat. It is metabolized to benazeprilat by hepatic esterases. Benazepril inhibits the in vitro enzymatic activity of partially purified ACE isolated from rabbit lung (IC₅₀ = 2 nM). Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.
Biovision | B2138 | Benazepril hydrochloride DataSheet
Alternate Name/Synonyms: (3S)-3-[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid Hydrochloride; CGS 14824A
Appearance: White solid
Formulation: N/A
CAS Number: 86541-74-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₂₈N₂O₅·HCl
Molecular Weight: 460.96
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml) or H₂O (20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor
MDL Number: MFCD00895734
PubChem CID: 5362123
SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl
InChi: InChI=1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20-;/m0./s1
InChi Key: VPSRQEHTHIMDQM-FKLPMGAJSA-N
