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Product Description
4-Aminonaphthalimide is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 180 nM. It inhibits radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation.
4-Aminonaphthalimide is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 180 nM. It inhibits radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation.
Biovision | B3134 | 4-Aminonaphthalimide DataSheet
Alternate Name/Synonyms: 6-aminobenzo[de]isoquinoline-1,3-dione; 4-Amino-1,8-naphthalimide; 4-Aminonaphthalene-1,8-dicarboximide; 7-Amino-3-hydroxy-1H-benzo[de]isoquinolin-1-one; 4-ANI
Appearance: Orange powder
Formulation:
CAS Number: 1742-95-6
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₁₂H₈N₂O₂
Molecular Weight: 212.2
Cell-Permeable?: TRUE
Purity: ≥ 95%
Solubilities: ~1 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of PARP
MDL Number: MFCD00006921
PubChem CID: 1720
SMILES: C1=CC2=C(C=CC3=C2C(=C1)C(=O)NC3=O)N
InChi: InChI=1S/C12H8N2O2/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(15)14-12(8)16/h1-5H,13H2,(H,14,15,16)
InChi Key: SSMIFVHARFVINF-UHFFFAOYSA-N
