Product Description
Cell-permeable. A structurally novel activator of SIRT1 (EC₅₀ = 1 µM). Displays selectivity over SIRT2 and 3 (EC₅₀ = 25 and 50 µM respectively).
BML-278 is a structurally novel activator of SIRT1 (EC₅₀ = 1 µM).
Biovision | 2379 | BML-278 DataSheet
Alternate Name/Synonyms: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
Appearance: Off-white solid
Formulation: N/A
CAS Number: N/A
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₂₅NO₄
Molecular Weight: 391.46
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: DMSO (~ 5 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A SIRT1 activator
MDL Number: N/A
PubChem CID: N/A
SMILES: O=C(OCC)C1=CN(CC2=CC=CC=C2)C=C(C(OCC)=O)C1C3=CC=CC=C3
InChi: InChI=1S/C24H25NO4/c1-3-28-23(26)20-16-25(15-18-11-7-5-8-12-18)17-21(24(27)29-4-2)22(20)19-13-9-6-10-14-19/h5-14,16-17,22H,3-4,15H2,1-2H3
InChi Key: JOHFECBOWRGWJZ-UHFFFAOYSA-N