Product Description
L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.
L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.
Biovision | 9638 | L-778123 hydrochloride DataSheet
Alternate Name/Synonyms: 4-((5-((4-(3-chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 253863-00-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₀ClN₅O
Molecular Weight: 405.88
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent FPTase and GGPTase-I inhibitor
MDL Number: N/A
PubChem CID: 216453
SMILES: C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl
InChi: InChI=1S/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H
InChi Key: YNBSQYGTJLIPJS-UHFFFAOYSA-N