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Product Description
A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells.
PJ-34 is a potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM).
Biovision | 2319 | PJ-34 hydrochloride DataSheet
Alternate Name/Synonyms: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 344458-15-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₇N₃O₂.HCl
Molecular Weight: 331.8
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~30 mg/ml) or H₂O (~ 30 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent poly(ADP-ribose) polymerase (PARP) inhibitor
MDL Number: MFCD03452993
PubChem CID: 16219859
SMILES: CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.O.Cl
InChi: InChI=1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2
InChi Key: YCALIZUKAFUQCH-UHFFFAOYSA-N
