Product Description
Adipophilin is a 49 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47, S3-12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. ADFP is expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. ADFP expression has a role in clear cell renal carcinoma differentiation. Most recently, it has been discovered that patients with kidney cancers had high levels of ADFP in their urine, suggesting that ADFP could be an excellent marker for kidney cancer.
Biovision | 4597 | Adipophilin human recombinant DataSheet
Biomolecule/Target: Adipophilin
Synonyms: Adipose differentiation-related protein, ADRP, ADFP, MGC10598.
Alternates names: Adipose differentiation-related protein, ADRP, ADFP, MGC10598, Perilipin-2
Taglines: A major constituent of the globule surface
NCBI Gene ID #: 493806
NCBI Gene Symbol: SDF1
Gene Source: Human
Accession #: O62657
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: The activity is determined by its ability to chemoattract human T cells at 10 - 75 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 8.5 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from 0.5 mg/ml solution containing 20mM Tris pH 7.5, and 20 mM NaCl,
Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Amino acid sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM