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Product Description
Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
Biovision | 4713 | Cathepsin G Human Neutrophil DataSheet
Biomolecule/Target: N/A
Synonyms: Cathepsin G
Alternates names: Cathepsin G, CTSG
Taglines: Involved in connective tissue remodeling at sites of inflammation
NCBI Gene ID #: 5909
NCBI Gene Symbol: RARRES2
Gene Source: N/A
Accession #: Q99969
Recombinant: No
Source: Human Neutrophil
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): 2 to 4 units per mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-Ala-Ala-Pro-Phe-pNA (1 mM) per minute at 25°C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 23.5 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Salt- free lyophilized solid
Reconstitution Instructions: Deionized HO
Amino acid sequence: N/A
