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Product Description
Human Prostate Specific Membrane Antigen (PSMA), a tumor marker in prostate cancer encoded by FOLH1 gene, is a surface glycoprotein with high expression in prostate epithelium. PSMA expression level increases in primary and metastatic prostate cancer and the neovasculature of nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It is also recognized as a viable target for cancer therapy.
Biovision | P1304 | Human CellExp PSMA / FOLH1 C-His Tag human recombinant DataSheet
Biomolecule/Target: PSMA
Synonyms: Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase
Alternates names: Interleukin-29, IL-29, IFN-Lambda 1, Interferon-Lambda 1, Cytokine ZCYTO21, IL29, IFNL1, ZCYTO21.
Taglines: Extracellular Domain of PSMA fused to 6x His tag at the C-terminus.
NCBI Gene ID #: 282618
NCBI Gene Symbol: IL29
Gene Source: Human
Accession #: Q8IU54
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Test in process
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 20 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized from filtered PBS (pH 7.4) with Trehalose (5%)
Reconstitution Instructions: Reconstitute in sterile dHO not less than 100 g/ml. This solution can then be diluted into other aqueous buffers
Amino acid sequence: N/A
