Shop by Category

Biovision Recombinant

Biovision Complete Product Catalog

 

 

  1. Caspases are a family of protease enzymes that play crucial roles in programmed cell death (apoptosis) and inflammation. They are involved in various cellular processes such as cell differentiation, proliferation, and immune response.
  2. Caspases are categorized into two main groups: initiator caspases (such as caspase-8 and caspase-9) and executioner caspases (such as caspase-3, caspase-6, and caspase-7).
  3. Initiator caspases are responsible for initiating apoptosis by activating executioner caspases, which then carry out the dismantling of the cell.
  4. Recombinant Biovision caspases are caspases that are produced using recombinant DNA technology. Recombinant proteins are generated by expressing the gene encoding the protein of interest in a host organism, typically bacteria, yeast, or mammalian cells.
  5. Our recombinant caspases are used for research to study apoptosis, inflammation, and other cellular processes. They offer several advantages over native caspases purified from tissues, including higher purity, greater yield, and consistency between batches.
  6. BioVision offers a range of recombinant caspases for research purposes. These recombinant proteins are used to investigate the molecular mechanisms of apoptosis and inflammation, as well as to develop novel therapeutic strategies for diseases associated with dysregulated cell death pathways.
  7. Biovision spases are important protease enzymes involved in cell death and inflammation, and recombinant caspases are artificially produced versions of these enzymes that are used in research to study their functions and regulatory mechanisms.
  8. BioVision offers recombinant caspases as part of its portfolio of research tools for investigating apoptosis, inflammation, and related cellular processes.

biovision.png

  • S-100 Protein, Bovine Brain

    Biovision | S-100 Protein, Bovine Brain | P1275

    Biological Significance: S-100 is a low molecular weight, cytoplasmic, calcium binding protein. It is traditionally found in the brain, heart and muscle tissue. S-100 has two subunits (alpha-chain and beta-chain) and exists in several different forms...

    £1,232
    Add to Cart
  • RSK3, Active

    Biovision | RSK3, Active | 7774

    RSK3 is a member of the RSK (ribosomal S6 kinase) family that encodes a 733-amino-acid protein with a unique N-terminal region containing a putative nuclear localization signal (1). RSK3 mRNA is widely expressed and is activated by growth factors, serum...

    £1,134
    Add to Cart
  • RSK2, Active

    Biovision | RSK2, Active | 7768

    RSK2 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK2 has been shown to mediate growth factor signaling via RAS and MAPK leading to the induction of CREB serine-133 phosphorylation and...

    £1,134
    Add to Cart
  • RSK1, Active

    Biovision | RSK1, Active | 7721

    The RSK (ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(rsk). RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the...

    £1,134
    Add to Cart
  • RIPK2, Active

    Biovision | RIPK2, Active | 7747

    RIPK2 (RIP2; RICK) is a death domain-containing protein kinase. Inohara identified cDNAs encoding a predicted 540-amino acid protein RICK, which contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and...

    £1,134
    Add to Cart
  • Recombinant Rat MIP-1  (CCL4)

    Biovision | Recombinant Rat MIP-1 (CCL4) | 4249

    Rat macrophage inflammatory protein-1 beta (MIP-1) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.Biovision | 4249 | Recombinant Rat MIP-1 CCL4...

    £850
    Add to Cart
  • Recombinant hSUMO2-Rhodamine

    Biovision | Recombinant hSUMO2-Rhodamine | 6414

    SUMO2-rhodamine 110 is a quenched fluorescent substrate for desumoylases, e.g. Sentrin protease 1 (SenP1) and SenP2. Cleavage of the amide bond between the C-terminal glycine of human SUMO2 and the fluorophore releases monoglycyl rhodamine 110 resulting...

    £1,656
    Add to Cart
  • Recombinant hSUMO2-AMC

    Biovision | Recombinant hSUMO2-AMC | 6413

    hSUMO2-AMC is prepared via the conjugation of 7-amino-4-methylcoumarin (AMC) to the C-terminal Gly of hSUMO2. This conjugation quenches the intrinsic fluorescence of AMC. Upon incubation with a protease recognizing hSUMOs, such as Senp1 or Senp2, AMC...

    £1,656
    Add to Cart
  • Recombinant hSUMO1-AMC

    Biovision | Recombinant hSUMO1-AMC | 6412

    hSUMO1-AMC is prepared via the conjugation of 7-amino-4-methylcoumarin (AMC) to the C-terminal Gly of hSUMO1. This conjugation quenches the intrinsic fluorescence of AMC. Upon incubation with a protease recognizing hSUMOs, such as Senp1 or Senp2, AMC...

    £1,656
    Add to Cart
  • RAET1E, human recombinant

    Biovision | RAET1E, human recombinant | 7327

    RAET1E belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. RAET1E and RAET1G protein differ from other RAET1 proteins in that they have type I...

    £1,066
    Add to Cart
  • QDPR, human recombinant

    Biovision | QDPR, human recombinant | 7821

    QDPR is a member of the short-chain dehydrogenases/reductase (SDR) family of enzymes. Functioning as a homodimer, QDPR plays an important role in the recycling of tetrahydrobiopterin (BH4), an essential cofactor for the hydroxylation of the aromatic...

    £1,296
    Add to Cart
  • PYCR1, human recombinant

    Biovision | PYCR1, human recombinant | 7368

    PYCR1 is a universal housekeeping enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. It forms a homopolymer and...

    £1,394
    Add to Cart
  • PTPN7, human recombinant

    Biovision | PTPN7, human recombinant | 7813

    PTPN7, also known as tyrosine-protein phosphatase non-receptor type 7 isoform 1, acts preferentially on tyrosine-phosphorylated MAPK1. This protein plays a role in the regulation of T and B-lymphocyte development and signal transduction. Recombinant...

    £1,232
    Add to Cart
  • PTEN, human recombinant

    Biovision | PTEN, human recombinant | 4838

    PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and...

    £1,788
    Add to Cart
  • PRPS1, human recombinant

    Biovision | PRPS1, human recombinant | 7828

    PRPS1, also known as ribose-phosphate pyrophosphokinase 1, is ubiquitously expressed in human tissues. This enzyme catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and...

    £1,198
    Add to Cart
  • Prothrombin, Human Plasma

    Biovision | Prothrombin, Human Plasma | 7684

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid...

    £576
    Add to Cart
  • Protein C, Human Plasma

    Biovision | Protein C, Human Plasma | 7682

    Protein C (PROC) is a vitamin K-dependent serine protease which regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. PROC is cleaved to its activated form by the thrombin-thrombomodulin...

    £772
    Add to Cart
  • Pro-MMP-8, human

    Biovision | Pro-MMP-8, human | 7784

    Human neutrophil collagenase (HNC) has been purified from extracts of fresh and outdated buffy coats and from exudates of phorbol myristate acetate-stimulated neutrophils. The MMP-8 present in the starting material can either be latent or active, or have...

    £806
    Add to Cart
  • Pro-MMP-2, mouse

    Biovision | Pro-MMP-2, mouse | 7780

    The proGelatinase A, a member of the matrix metalloproteinase (MMP) family, has been isolated from macrophages and fibroblasts. Gelatinase A hydrolyses several components of the extracellular matrix, e.g. the collagen types IV, V and XI and Gelatin...

    £1,362
    Add to Cart
  • Pro-MMP-13, human recombinant

    Biovision | Pro-MMP-13, human recombinant | 7785

    MMP-13 (Collagenase-3) was first identified in human mammacarcinoma (Freije et al., 1994, Willmroth et al. 1998) - probably induced by IL1- alpha and IL-1 beta - and shown to be glycosylated and the inactive zymogen displaying a relative molecular weight...

    £1,296
    Add to Cart
  • Prekallikrein, Human Plasma

    Biovision | Prekallikrein, Human Plasma | 7685

    Prekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates...

    £690
    Add to Cart
  • PPP1SS, human recombinant

    Biovision | PPP1SS, human recombinant | P1182

    PPP1CC, also known as serine/threonine-protein phosphatase PP1-gamma catalytic subunit, is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. This protein is involved in...

    £1,002
    Add to Cart
  • PPM1F, human recombinant

    Biovision | PPM1F, human recombinant | 7810

    PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus...

    £1,232
    Add to Cart
  • PPARG, Human Recombinant

    Biovision | PPARG, Human Recombinant | P1120

    Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear...

    £4,294
    Add to Cart
  • PPA1, human recombinant

    Biovision | PPA1, human recombinant | 7818

    PPA1 (Pyrophosphatase) belongs to the PPase family. This protein is an enzyme that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. The hydrolysis of inorganic pyrophosphate (PPi) to two phosphate ions is utilized in many...

    £1,232
    Add to Cart
  • PNP, human recombinant

    Biovision | PNP, human recombinant | 7831

    PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare...

    £1,232
    Add to Cart
  • Plasminogen, Human Plasma

    Biovision | Plasminogen, Human Plasma | 7549

    Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. Plasminogen is the inactive precursor of plasmin...

    £870
    Add to Cart
  • Plasmin, Human Plasma

    Biovision | Plasmin, Human Plasma | 4089

    Plasmin functions in fibrinolysis, fibrinogenolysis, as well as in the complement cascade. This protease has been prepared by using streptokinase to activate human plasma plasminogen.Biovision | 4089 | Plasmin Human Plasma DataSheetBiomolecule/Target:...

    £854
    Add to Cart
  • PKD2, Active

    Biovision | PKD2, Active | 7711

    PKD2 is a novel phorbol ester- and growth factor-stimulated serine/threonine kinase that contains two cysteine-rich motifs at the N terminus, a pleckstrin homology domain, and a catalytic domain (1). It exhibits the strongest homology to the...

    £1,164
    Add to Cart
  • PKCzeta, Active

    Biovision | PKCzeta, Active | 7718

    PKC (PKC zeta) is an atypical isoform of the PKC family. PKC is found in both particulate and soluble fractions and cannot be activated by phorbol ester. Treatment of cells with phorbol ester which activates PKC, , , and isoforms in NIH3T3 cells...

    £1,134
    Add to Cart
  • PKCnu, Active

    Biovision | PKCnu, Active | 7746

    PKCnu, also known as PKD3, is a members of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCnu is composed of 890 amino acid...

    £1,134
    Add to Cart
  • PKCmu, Active

    Biovision | PKCmu, Active | 7745

    Protein kinase Cmu (PKCmu) is a novel member of the protein kinase C (PKC) family that differs from the other isoenzymes in structural and enzymatic properties. It is characterized by the presence of a pleckstrin homology (PH) domain and an...

    £1,134
    Add to Cart
  • PKCeta, Active

    Biovision | PKCeta, Active | 7731

    PKC eta is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKC is predominantly...

    £1,134
    Add to Cart
  • PKCepsilon, Active

    Biovision | PKCepsilon, Active | 7753

    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved...

    £1,134
    Add to Cart
  • PKCa, Active

    Biovision | PKCa, Active | 7714

    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved...

    £1,134
    Add to Cart
  • PKC gamma, Active

    Biovision | PKC gamma, Active | 7764

    PKC is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKC is translocated...

    £1,134
    Add to Cart
  • PKC delta, Active

    Biovision | PKC delta, Active | 7739

    Protein kinase C delta (PKC delta) is a member of the protein kinase C (PKC) family of serine-threonine kinases. It is a 79 kd protein kinase that shows strict dependence on the presence of phospholipids, but shows no activation by Ca2+ (1)...

    £1,134
    Add to Cart
  • PKC BetaII, Active

    Biovision | PKC BetaII, Active | 7704

    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in...

    £1,134
    Add to Cart
  • PKC  iota, Active

    Biovision | PKC iota, Active | 7705

    PKC is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC showed greatest homology to PKC zeta, with 72% identity overall rising to 84% in the catalytic domain. In contrast, the homology of PKC to the...

    £1,134
    Add to Cart
  • PKAcb, Active

    Biovision | PKAcb, Active | 7744

    Most of the effects of cAMP are mediated through the phosphorylation of target proteins on serine or threonine residues by the cAMP-dependent protein kinase (PKA). The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic...

    £1,134
    Add to Cart
  • PKAca, Active

    Biovision | PKAca, Active | 7743

    Most of the effects of cAMP are mediated through the phosphorylation of target proteins on serine or threonine residues by the cAMP-dependent protein kinase (AMPK). The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two...

    £1,134
    Add to Cart
  • PKA cg, Active

    Biovision | PKA cg, Active | 7728

    PKA C- (PKAcg) is a third isoform of the catalytic subunit of cAMP-dependent protein kinase. It was isolated from a human testis cDNA library and was clearly derived from a gene distinct from C- and C- and showed tissue-specific expression. Whereas at...

    £1,134
    Add to Cart
  • PIM2, Active

    Biovision | PIM2, Active | 7730

    Baytel et al. identified a deduced 334-amino acid sequence of the clone, which showed 90% identity with the mouse Pim2 protein. Like mouse Pim2, the human protein appears to be a serine threonine kinase. Northern blot analysis detected 2 PIM2 transcripts...

    £1,134
    Add to Cart
  • Pim 1, Active

    Biovision | Pim 1, Active | 7742

    The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T-cell lymphomas in mice, Pim1 is...

    £1,134
    Add to Cart
  • PGK2, human recombinant

    Biovision | PGK2, human recombinant | 7820

    PGK2 is a testis-specific form of phosphoglycerate kinase. Initially assumed to be a pseudogene, this protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate,...

    £1,526
    Add to Cart
  • PGK1, human recombinant

    Biovision | PGK1, human recombinant | 7819

    Phosphoglycerate kinase 1 (PGK1) is an X-linked enzyme that plays a key role in the glycolytic pathway. The gene encoding the erythrocyte enzyme PGK1 and it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) as a...

    £1,232
    Add to Cart