Quick view Biovision | Quercetin, Dihydrate | 1773 A plant-derived flavanoid. Cell-permeable. Inhibits PIM1 kinase (IC₅₀ = 1.1 µM), PI 3-Kinase (IC₅₀ = 3.8 µM) and phospholipase A2 (IC₅₀ = 2 µM). Also acts as an anti-tumor agent; induces apoptosis... MSRP: Was: Now: £330 - £674 Choose Options Compare
Quick view Biovision | Pyrvinium Pamaote | B1593 Pyrvinium pamoate (PP) is a quinoline-derived cyanine dye that displays anthelmintic properties and therapeutic function against animal-like protists such as Cryptosporidium parvum and Plasmodium... MSRP: Was: Now: £576 - £1,788 Choose Options Compare
Quick view Biovision | Pyroxamide | 2189 Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.Pyroxamide is a potent... MSRP: Was: Now: £394 - £1,180 Choose Options Compare
Quick view Biovision | Pyripyropene A | B1910 Pyripyropropene A is isolated from Aspergillus fumigatus FO-1289. Acts as a highly specific inhibitor of acyl-coenzyme A: cholesterol acetyltransferase 2 (ACAT2). Antiatherogenic and... MSRP: Was: Now: £1,066 - £1,624 Choose Options Compare
Quick view Biovision | Pyrintegrin | 1729 A novel small molecule that helps in promoting human embryonic stem cell (hESC) survival by > 30-fold.The dramatic increase in cell survival has been attributed to the protection of the cell surface... MSRP: Was: Now: £592 - £1,870 Choose Options Compare
Quick view Biovision | PXD101 | 2480 A potent histone deacetylase (HDAC) activity inhibitor. It inhibits HDAC activity in HeLa cell extracts with an IC₅₀ of 27 nM. Belinostat significantly increases acetylation of histones H3 and H4 and... MSRP: Was: Now: £410 - £1,134 Choose Options Compare
Quick view Biovision | PX-866 | 1965 Cell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.PX-866 is a... MSRP: Was: Now: £394 - £1,066 Choose Options Compare
Quick view Biovision | PX-478 hydrochloride | B1033 PX-478 hydrochloride is an inhibitor of HIF-1α (IC₅₀ of 20-30 μM) with potential antineoplastic activity. PX-478 inhibits HIF-1alpha protein levels and transactivation in a variety of cancer cell... MSRP: Was: Now: £606 - £1,918 Choose Options Compare
Quick view Biovision | PX 12 | 2217 PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α, VEGF and iNOS (IC₅₀ values are 7.2, ~10 and 18.1 μM respectively). Also known to... MSRP: Was: Now: £542 - £1,722 Choose Options Compare
Quick view Biovision | Puromycin Dihydrochloride | 1860 A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in... MSRP: Was: Now: £394 - £3,916 Choose Options Compare
Quick view Biovision | PU-H71 | 9649 PU-H71 is a potent Heat Shock Protein 90 (Hsp90) inhibitor (IC₅₀ = 50 nM). Also inhibits cell growth in a range of breast cancer cell lines (IC₅₀ values are 17, 31, 65, 87 and 140 nM for SKBr3,... MSRP: Was: Now: £542 - £1,656 Choose Options Compare
Quick view Biovision | PTC-124 | 9421 PTC-124 has been reported to help the ribosome skip over the premature stop, restore production of functional protein, and thereby potentially treat these genetic diseases. In a mouse model of cystic... MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Biovision | PT1 | B2035 PT1 is an AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC = 0.3 μM). Selectively increases the activity of γ1- but not γ3-containing complexes... MSRP: Was: Now: £806 - £2,622 Choose Options Compare
Quick view Biovision | PSI-7977 | 2715 PSI-7977 is a phosphoramidate nucleotide prodrug for the treatment of hepatitis virus. It acts as a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase.PSI-7977 is a phosphoramidate... MSRP: Was: Now: £738 - £2,444 Choose Options Compare
Quick view Biovision | Pseudolaric Acid B | 2512 Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempferi, that displays interesting antifungal, antifertility, and cytotoxic activity against multidrug resistant cell... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | PS48 | 1869 An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently... MSRP: Was: Now: £428 - £2,900 Choose Options Compare
Quick view Biovision | PS-341 | 1846 A potent (Ki = 0.6 nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC₅₀ of 0.1 µM.PS-341 is a... MSRP: Was: Now: £410 - £968 Choose Options Compare
Quick view Biovision | Proteasome Substrate, Fluorogenic | 1832 A fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored... MSRP: Was: Now: £394 - £1,036 Choose Options Compare
Quick view Biovision | Proteasome Substrate III, Fluorogenic | B2060 Proteasome Substrate III is a fluorogenic substrate for the peptidylglutamyl-peptide hydrolyzing (caspase-like) activity of the proteasome. Excitation: 380 nm. Emission: 460 nmProteasome Substrate... MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Biovision | Proteasome Substrate II, Fluorogenic | B2059 Proteasome Substrate II is a sensitive fluorogenic substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release... MSRP: Was: Now: £410 - £1,134 Choose Options Compare
Quick view Biovision | Prodigiosin | 2311 Isolated from Serratia marcescens. Displays antibacterial, anticancer, cytotoxic, immunosuppressive, and antiproliferative activities. Prodigiosin induces apoptosis in hematopoietic cancer cells and... MSRP: Was: Now: £478 - £1,330 Choose Options Compare
Quick view Biovision | PRL-3 Inhibitor | B1825 P0108 is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3) (IC₅₀ = 0.9 μM). It reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model. Sensitizes... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | Pritelivir mesylate | B2154 Pritelivir is a potent helicase primase inhibitor. It inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | Prexasertib mesylate | B2067 Prexasertib is a potent inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. Upon administration, prexasertib selectively binds to chk1, thereby preventing activity of chk1... MSRP: Was: Now: £640 - £2,048 Choose Options Compare
Quick view Biovision | PQR-309 | B1300 PQR-309 is a potent pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PQR-309 inhibits the PI3K... MSRP: Was: Now: £606 - £1,918 Choose Options Compare
Quick view Biovision | PPARγ Antagonist, G3335 | 1979 Cell-permeable. A dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀= 31... MSRP: Was: Now: £394 - £640 Choose Options Compare
Quick view Biovision | PPACK II, trifluoroacetate | B2151 PPACKII is a specific and irreversible inhibitor of glandular and plasma kallikreins. Human tissue kallikreins (hKs) are a class of secreted serine proteases that involved in the release of... MSRP: Was: Now: £904 - £3,426 Choose Options Compare
Quick view Biovision | PP3 | 1797 A negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR kinase at an IC₅₀ = 2.7 μM.PP3 is a negative control for the Src family kinase inhibitor... MSRP: Was: Now: £394 - £1,036 Choose Options Compare
Quick view Biovision | Ponasterone A | 2183 A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to muristerone A. Induces expression of β-galactosidase to levels similar to those... MSRP: Was: Now: £428 - £1,134 Choose Options Compare
Quick view Biovision | Polymyxin B sulfate | 2496 Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters... MSRP: Was: Now: £576 - £1,428 Choose Options Compare
Quick view Biovision | Podophyllotoxin | 2767 Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.Podophyllotoxin is a potent inhibitor of... MSRP: Was: Now: £380 - £674 Choose Options Compare
Quick view Biovision | PLX-7904 | B1249 PLX7904 is a potent and selective paradox-breaker RAF inhibitor. PLX7904 efficiently inhibits activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant... MSRP: Was: Now: £674 - £2,116 Choose Options Compare
Quick view Biovision | PLX-4032 | 2235 Cell-permeable. A potent, selective and ATP-competitive, inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. PLX-40432 selectively binds to the ATP-binding site of BRAF(V600E)... MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Biovision | PLX-3397 | 9617 PLX3397 is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. PLX3397 binds to and inhibits phosphorylation of stem cell factor... MSRP: Was: Now: £542 - £1,460 Choose Options Compare
Quick view Biovision | Pluronic® F-127, MegPure™ Detergent, 10% Solution, Sterile-Filtered | 2731 Pluronic® F-127 is a non-ionic detergent useful for isolation of membrane proteins. It has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological... MSRP: Was: Now: £410 - £3,360 Choose Options Compare
Quick view Biovision | Pluronic® F-127 | 2730 Pluronic® F-127 is a non-ionic detergent useful for isolation of membrane proteins. It has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological... MSRP: Was: Now: £444 - £984 Choose Options Compare
Quick view Biovision | Plinabulin | B2049 Plinabulin (NPI-2358) is a vascular disrupting agent (VDA). Plinabulin binds to the colchicine binding site of β-tubulin preventing polymerization and disrupting the cytoplasmic microtubule network... MSRP: Was: Now: £542 - £1,656 Choose Options Compare
Quick view Biovision | Plasmin substrate (colorimetric) | B2411 A chromogenic plasmin substrate. Plasmin cleaves p-nitroanilide (pNA) releasing p-nitroanilne that can be quantified using a spectrophotometer or a microtiter plate reader at ~ 405 nm.Plasmin... MSRP: Was: Now: £640 - £1,968 Choose Options Compare
Quick view Biovision | PKC412 | 2052 Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent... MSRP: Was: Now: £592 - £1,820 Choose Options Compare
Quick view Biovision | PK 11195 | 2054 Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays... MSRP: Was: Now: £394 - £1,050 Choose Options Compare
Quick view Biovision | PJ-34 hydrochloride | 2319 A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in... MSRP: Was: Now: £364 - £920 Choose Options Compare
Quick view Biovision | Pixantrone maleate | 1958 An analog of Mitoxantrone (Cat. No. 1885-50, 250) that displays antitumor properties with fewer toxic effects on cardiac tissue. Acts as a topoisomerase II poison and intercalating agent.Pixantrone... MSRP: Was: Now: £428 - £1,164 Choose Options Compare
Quick view Biovision | Pitavastatin calcium | B2090 Pitavastatin calcium is a synthetic inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase, (Ki = 1.7 nM). It lowers both total cholesterol and low density lipoprotein (LDL)... MSRP: Was: Now: £410 - £1,134 Choose Options Compare
Quick view Biovision | Piperlonguminine | 1988 Piperlonguminine is a known alkaloid amide from peppers, including Piper divaricatum. Acts as a potent anticancer agent. Displays inhibitory effect on alpha-melanocyte-stimulating hormone... MSRP: Was: Now: £394 - £1,018 Choose Options Compare
Quick view Biovision | PIK75 | B1668 PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.PIK-75 is a p110α... MSRP: Was: Now: £394 - £934 Choose Options Compare
Quick view Biovision | PIK-293 | B1658 PIK-293 is a PI3K inhibitor.PIK-293 is a PI3K inhibitor.Biovision | B1658 | PIK-293 DataSheetAlternate Name/Synonyms: PIK-293; PIK 293; PIK293;... MSRP: Was: Now: £738 - £2,426 Choose Options Compare
Quick view Biovision | Picropodophyllotoxin | 2765 A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R... MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Biovision | Pibrentasvir | B2168 Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the viral RNA replication and virion assembly.Pibrentasvir is a direct acting antiviral agent... MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Biovision | PI3K-α Inhibitor | B1869 PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2... MSRP: Was: Now: £640 - £2,048 Choose Options Compare
Quick view Biovision | PI3-Kɣ Inhibitor, AS-605240 | 1780 Cell-permeable. A potent and selective inhibitor of PI 3-kinase γ (PI3Kγ) (IC₅₀ = 8 nM). Displays >33-fold selectivity over PI3Kδ and PI3Kβ and 7.5-fold selectivity over PI3Kα.AS-605240 is a potent... MSRP: Was: Now: £410 - £1,050 Choose Options Compare
Quick view Biovision | SB1518 (Pacritinib) | 2450 A potent JAK2/FLT3 inhibitor. Displays equipotent activity against JAK2 (I₅₀ = 23 nM) and FLT3 (IC₅₀ = 22 nM). SB1518 displays potent anti-proliferative effects on myeloid and lymphoid cell lines... MSRP: Was: Now: £542 - £1,656 Choose Options Compare
Quick view Biovision | Phleomycin | 2724 Phleomycin is an antibiotic produced by Streptomyces verticullus and is structurally related to Bleomycin. Used as a selective agent in transformation experiments with mammalian cells, plant cells... MSRP: Was: Now: £478 - £1,100 Choose Options Compare
Quick view Details Biovision | Quercetin, Dihydrate | 1773 MSRP: Was: Now: £330 - £674 Choose Options Compare
Quick view Details Biovision | Pyrvinium Pamaote | B1593 MSRP: Was: Now: £576 - £1,788 Choose Options Compare
Quick view Details Biovision | Pyroxamide | 2189 MSRP: Was: Now: £394 - £1,180 Choose Options Compare
Quick view Details Biovision | Pyripyropene A | B1910 MSRP: Was: Now: £1,066 - £1,624 Choose Options Compare
Quick view Details Biovision | Pyrintegrin | 1729 MSRP: Was: Now: £592 - £1,870 Choose Options Compare
Quick view Details Biovision | PX-478 hydrochloride | B1033 MSRP: Was: Now: £606 - £1,918 Choose Options Compare
Quick view Details Biovision | Puromycin Dihydrochloride | 1860 MSRP: Was: Now: £394 - £3,916 Choose Options Compare
Quick view Details Biovision | Pseudolaric Acid B | 2512 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | Proteasome Substrate, Fluorogenic | 1832 MSRP: Was: Now: £394 - £1,036 Choose Options Compare
Quick view Details Biovision | Proteasome Substrate III, Fluorogenic | B2060 MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Details Biovision | Proteasome Substrate II, Fluorogenic | B2059 MSRP: Was: Now: £410 - £1,134 Choose Options Compare
Quick view Details Biovision | Prodigiosin | 2311 MSRP: Was: Now: £478 - £1,330 Choose Options Compare
Quick view Details Biovision | PRL-3 Inhibitor | B1825 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | Pritelivir mesylate | B2154 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | Prexasertib mesylate | B2067 MSRP: Was: Now: £640 - £2,048 Choose Options Compare
Quick view Details Biovision | PPARγ Antagonist, G3335 | 1979 MSRP: Was: Now: £394 - £640 Choose Options Compare
Quick view Details Biovision | PPACK II, trifluoroacetate | B2151 MSRP: Was: Now: £904 - £3,426 Choose Options Compare
Quick view Details Biovision | Ponasterone A | 2183 MSRP: Was: Now: £428 - £1,134 Choose Options Compare
Quick view Details Biovision | Polymyxin B sulfate | 2496 MSRP: Was: Now: £576 - £1,428 Choose Options Compare
Quick view Details Biovision | Podophyllotoxin | 2767 MSRP: Was: Now: £380 - £674 Choose Options Compare
Quick view Details Biovision | Pluronic® F-127, MegPure™ Detergent, 10% Solution, Sterile-Filtered | 2731 MSRP: Was: Now: £410 - £3,360 Choose Options Compare
Quick view Details Biovision | Pluronic® F-127 | 2730 MSRP: Was: Now: £444 - £984 Choose Options Compare
Quick view Details Biovision | Plinabulin | B2049 MSRP: Was: Now: £542 - £1,656 Choose Options Compare
Quick view Details Biovision | Plasmin substrate (colorimetric) | B2411 MSRP: Was: Now: £640 - £1,968 Choose Options Compare
Quick view Details Biovision | PJ-34 hydrochloride | 2319 MSRP: Was: Now: £364 - £920 Choose Options Compare
Quick view Details Biovision | Pixantrone maleate | 1958 MSRP: Was: Now: £428 - £1,164 Choose Options Compare
Quick view Details Biovision | Pitavastatin calcium | B2090 MSRP: Was: Now: £410 - £1,134 Choose Options Compare
Quick view Details Biovision | Piperlonguminine | 1988 MSRP: Was: Now: £394 - £1,018 Choose Options Compare
Quick view Details Biovision | Picropodophyllotoxin | 2765 MSRP: Was: Now: £444 - £1,262 Choose Options Compare
Quick view Details Biovision | Pibrentasvir | B2168 MSRP: Was: Now: £478 - £1,394 Choose Options Compare
Quick view Details Biovision | PI3K-α Inhibitor | B1869 MSRP: Was: Now: £640 - £2,048 Choose Options Compare
Quick view Details Biovision | PI3-Kɣ Inhibitor, AS-605240 | 1780 MSRP: Was: Now: £410 - £1,050 Choose Options Compare
Quick view Details Biovision | SB1518 (Pacritinib) | 2450 MSRP: Was: Now: £542 - £1,656 Choose Options Compare
Quick view Details Biovision | Phleomycin | 2724 MSRP: Was: Now: £478 - £1,100 Choose Options Compare
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