Quick view Biovision | 4-Hydroxyquinazoline | B3148 4-Hydroxyquinazoline is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 9.5 μM. 4-hydroxyquinazoline improves the recovery of high-energy phosphates (ATP,... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | ICR-1 AM | B3147 ICR-1 is a red fluorescent calcium (Ca2+) indicator for intracellular Ca2+ measurements. It provides deeper tissue penetration and dramatic background reduction in tissues that have high... MSRP: Was: Now: £1,460 - £2,214 Choose Options Compare
Quick view Biovision | Fluo-4 AM | B3146 Fluo-4 is a widely used green fluorescent, intracellular calcium (Ca²⁺) indicator. Fluo-4 AM is the membrane permeable form of the calcium indicator. Masking the negative charge using non-polar,... MSRP: Was: Now: £1,100 - £1,656 Choose Options Compare
Quick view Biovision | IPG-4 TMA⁺ Salt | B3145 IPG-4 is a yellow-green fluorescent, intracellular potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. It is a small, synthetic... MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Biovision | IPG-4 AM | B3144 IPG-4 is a yellow-green fluorescent, intracellular potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. It is a small, synthetic... MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Biovision | IPG-2 TMA⁺ Salt | B3143 IPG-2 is a yellow-green fluorescent, intracellular potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. It is a small, synthetic... MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Biovision | IPG-2 AM | B3142 IPG-2 is a yellow-green fluorescent, intracellular potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. It is a small, synthetic... MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Biovision | IPG-1 TMA+ Salt | B3141 IPG-1 is a small, synthetic fluorochrome which incorporates a K⁺-binding moiety. When K⁺ binds, the quenching is relieved and the fluorescence dramatically increases. IPG-1 has Ex/Em: 525 nm/545 nm... MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Biovision | IPG-1 AM | B3140 IPG-1 is a yellow-green fluorescent, intracellular potassium (K⁺) indicator for measuring changes at most intracellular K⁺ concentrations. It is a small, synthetic fluorochrome which incorporates a... MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Biovision | NCC007 | B3139 NCC007 is an inhibitor of casein kinase I (CKI) and a modulator of circadian rhythm. It inhibits CKIα and CKIδ with an IC₅₀ of 1.8 and 3.6 μM. It shows stronger period effects (0.32 μM for 5 h period... MSRP: Was: Now: £606 - £1,934 Choose Options Compare
Quick view Biovision | ING-2 TMA+ Salt | B3138 ING-2 is a yellow-green fluorescent intracellular sodium Na⁺ indicator. It is a small, synthetic fluorochrome fused with a Na⁺-binding moiety. When Na⁺ binds to ING-2, the quenching is relieved, and... MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Biovision | ING-2 AM | B3137 ING-2 AM is the membrane permeable form of the sodium indicator ING-2 (Cat. No. B3138). Masking the negative charge using non-polar, ester-linked moieties (AM ester) allows the molecule to enter... MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Biovision | Longdaysin | B3136 Longdaysin is a potent modulator of circadian rhythm. It slows the circadian clock both in cultured mammalian cells and zebrafish. It inhibits the protein kinases CKIδ, CKIα, ERK2, and CDK7... MSRP: Was: Now: £508 - £1,542 Choose Options Compare
Quick view Biovision | BMS-P5 | B3135 BMS-P5 is a potent and selective inhibitor of peptidylarginine deiminase 4 (PAD4). It significantly reduces Multiple myeloma-cells induced citrullination of histone H3 and formation of neutrophil... MSRP: Was: Now: £560 - £1,738 Choose Options Compare
Quick view Biovision | 4-Aminonaphthalimide | B3134 4-Aminonaphthalimide is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP with an IC₅₀ of 180 nM. It inhibits radiation-induced PARP in cancer cells, potentiating the cytotoxicity... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | 3-Cyano-7-ethoxycoumarin | B3133 3-Cyano-7-ethoxycoumarin is a fluorogenic substrate for cytochrome P450. It is metabolized to 3-cyano-7-hydroxycoumarin with an excitation/emission maxima of 408/450 nm, respectively. It can be used... MSRP: Was: Now: £394 - £1,082 Choose Options Compare
Quick view Biovision | 3,6-Dihydroxyflavone | B3132 3,6-Dihydroxyflavone is a flavanoid which shows anticancer activity. It suppresses breast carcinogenesis by upregulation of miR-34a and downregulation of miR-21 at a concentration of 20 μM... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | Penicillin G Potassium | B3131 Penicillin is a broad-spectrum β-lactam antibiotic. It binds to penicillin binding proteins (PBP). PBP catalyzes the synthesis of peptidoglycan, which is an important component of the bacterial cell... MSRP: Was: Now: £380 - £806 Choose Options Compare
Quick view Biovision | 2-Guanidinobenzimidazole | B3130 2-Guanidinobenzimidazole is an inhibitor of voltage-gated proton channel Hv1. It inhibits Hv1 proton conduction (10 μM-200 μM) by binding to the voltage-sensing domain. Inhibition of excessive Hv1... MSRP: Was: Now: £364 - £904 Choose Options Compare
Quick view Biovision | 2-Chloroadenosine | B3129 2-Chloroadenosine is an adenosine receptor agonist. It binds to adenosine A1, A2A, and A3 receptors with Ki values of 300, 80, and 1900 nM, respectively. It significantly decreases seizures in a rat... MSRP: Was: Now: £478 - £1,410 Choose Options Compare
Quick view Biovision | 2-Bromopalmitic acid | B3128 2-Bromopalmitic acid is a fatty acid oxidation inhibitor. It inhibits carnitine palmitoyltransferase-1 (CPT1) and is also an inhibitor of protein palmitoylation. It significantly increases retinoic... MSRP: Was: Now: £364 - £836 Choose Options Compare
Quick view Biovision | 1-EBIO | B3127 1-EBIO is an activator of Ca2+- and cAMP-sensitive K+ channels. It stimulates a sustained Cl- secretory response with an EC₅₀ of 490 μM. It induces cardiogenesis of pluripotent stem cells.1-EBIO is... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | IM156 | B3126 IM156 is a bioenergetic biguanide derivative which blocks mitochondrial complex I and an activator of AMP-activated protein kinase (AMPK). It is a derivative of metformin. IM156 causes energy... MSRP: Was: Now: £462 - £1,346 Choose Options Compare
Quick view Biovision | TVB-2640 | B3125 TVB-2640 is an oral, selective fatty acid synthase (FASN) inhibitor. It reduces hepatic de novo lipogenesis in males with metabolic abnormalities. It is being evaluated in phase 2 clinical trials to... MSRP: Was: Now: £640 - £2,066 Choose Options Compare
Quick view Biovision | AZD-4205 | B3124 AZD-4205 is a highly selective Janus Kinase 1 (JAK1) inhibitor with an IC₅₀ of 0.07 μM. It shows antitumor activity in combination with the EGFR inhibitor, osimertinib, in a preclinical... MSRP: Was: Now: £394 - £1,082 Choose Options Compare
Quick view Biovision | 1,4-DPCA | B3123 1,4-DPCA is a competitive inhibitor of prolyl 4-hydroxylase. It inhibits isolated chick prolyl 4-hydroxylase and procollagen synthesis in human foreskin fibroblasts with an IC₅₀ value of 3.6 and 2.4... MSRP: Was: Now: £526 - £1,590 Choose Options Compare
Quick view Biovision | 1,10-Phenanthroline | B3122 1,10-Phenanthroline is a metal chelator and inhibitor of metalloproteases. 1,10-Phenanthrine acts as a fungistatic against P. verrucosa (MIC = 0.8 μg/ml) and inhibits zinc-induced P. verrucosa... MSRP: Was: Now: £364 - £508 Choose Options Compare
Quick view Biovision | Ponesimod | B3121 Ponesimod is a potent agonist of sphingosine-1-phosphate receptor 1 (S1P1) receptor. It reduces the circulating lymphocytes at a dose of 3-100 mg/kg in a rat model. It selectively activates S1P1 in a... MSRP: Was: Now: £560 - £1,738 Choose Options Compare
Quick view Biovision | Trilaciclib dihydrochloride | B3120 Trilaciclib dihydrochloride is a CDK4/6 inhibitor which reduces chemotherapy-induced myelosuppression. It induces a G1 cell-cycle arrest in CDK4/6-dependent HS68 cells with an EC₅₀ of 30 nM. It is... MSRP: Was: Now: £722 - £2,394 Choose Options Compare
Quick view Biovision | Acefylline | B3119 Acefylline is a xanthine derivative which acts as potential Peptidylarginine deiminase (PAD) activator. It increases the in vitro deimination of filaggrin by PAD1 and PAD3 at a concentration of 200... MSRP: Was: Now: £364 - £934 Choose Options Compare
Quick view Biovision | Fluvoxamine Maleate | B3118 Fluvoxamine is an inhibitor of 5-hydroxytryptamine (5-HT) re-uptake. It inhibits the uptake of 5-hydroxytryptamine in guinea-pig blood platelets with a pI₅₀ (the negative logarithm of the molar... MSRP: Was: Now: £364 - £934 Choose Options Compare
Quick view Biovision | Otenabant Hydrochloride | B3117 Otenabant is a novel cannabinoid type 1 (CB1) receptor antagonist. It is effective at subnanomolar concentrations at human CB1 receptors in binding and functional assays, with Ki values of 0.7 nM and... MSRP: Was: Now: £444 - £1,278 Choose Options Compare
Quick view Biovision | Sarcosine | B3116 Sarcosine is an intermediate in the metabolism of glycine. Sarcosine is an antagonist of glycine transporter-1 (GlyT1) with an IC₅₀ value of 91 μM. It has beneficial effects in schizophrenia... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | Perphenazine | B3115 Perphenazine is a dopamine receptor antagonist. It binds to Dopamine receptors D₂, D₃ and D₄ with Ki values of 0.56 nM, 0.43 nM and 28.5 nM respectively. It also binds to serotonin receptors 5-HT1A,... MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Biovision | Tiagabine hydrochloride | B3114 Tiagabine is a selective inhibitor of GABA transporter 1 (GAT-1) and a GABA uptake inhibitor. It shows an IC₅₀ of 49 nM for GAT-1 expressed in CHO cells. It reduces allodynia in a rodent model of... MSRP: Was: Now: £364 - £934 Choose Options Compare
Quick view Biovision | Labetalol Hydrochloride | B3113 Labetalol is a competitive antagonist of β- and α-adrenergic receptors. It is used as an antihypertensive agent. It also shows antioxidant acitivity with an IC₅₀ of 16.5 mg/L in... MSRP: Was: Now: £428 - £1,214 Choose Options Compare
Quick view Biovision | Metoclopramide Hydrochloride | B3112 Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | UNC2250 | B3111 UNC2250 is an inhibitor of Mer receptor tyrosine kinase. It inhibits steady-state phosphorylation of endogenous Mer with an IC₅₀ of 9.8 nM. It blocks ligand-stimulated activation of a chimeric... MSRP: Was: Now: £560 - £1,738 Choose Options Compare
Quick view Biovision | GGTI-298 Trifluoroacetate | B3110 GGTI-298 is an inhibitor of geranylgeranyltransferase I. This enzyme transfers geranylgeranyl group to proteins containing a CAAX sequence in which X is leucine or isoleucine. GGTI-298 inhibits the... MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Biovision | FPH1 | B3109 FPH1 also known as Functional Proliferation Hit 1 induces functional proliferation of hepatocytes in vitro. It promotes the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps)... MSRP: Was: Now: £526 - £1,606 Choose Options Compare
Quick view Biovision | Osilodrostat | B3108 Osilodrostat is a potent inhibitor of the enzymes 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), which catalyze the final steps of cortisol and aldosterone biosynthesis, respectively,... MSRP: Was: Now: £658 - £2,116 Choose Options Compare
Quick view Biovision | Opicapone | B3107 Opicapone is a potent inhibitor of catechol-O-methyltransferase (COMT). It inhibits rat peripheral COMT with ED₅₀ values below 1.4 mg/kg up to 6 h post-administration. It is approved for use as... MSRP: Was: Now: £444 - £1,278 Choose Options Compare
Quick view Biovision | Ripretinib | B3106 Ripretinib is an inhibitor of receptor tyrosine kinase (KIT) and platelet derived growth factor receptor A (PDGFRA). In vitro kinase inhibition studies show that ripretinib inhibits wild-type KIT and... MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Biovision | DMSO (Anhydrous) | B3105 DMSO is a highly polar aprotic organic solvent. It is widely used to dissolve both polar and nonpolar compound. It penetrates biological membranes and is used as a vehicle for topical application of... MSRP: Was: Now: £806 - £2,376 Choose Options Compare
Quick view Biovision | GSK-923295 | B3104 GSK923295 is an allosteric inhibitor of CENP-E kinesin motor ATPase activity. It inhibits CENP-E microtubule-stimulated ATPase activity with a Ki of 3.2 ± 0.2 nM. It inhibits the growth of tumor cell... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | AZD-2461 | B3103 AZD-2461 is an inhibitor of poly(ADP-ribose) polymerase (PARP). It inhibits PARP1 and PARP2 with IC₅₀ values of 5 nM and 2 nM. It has lower affinity for P-glycoprotein and suppresses the development... MSRP: Was: Now: £428 - £1,214 Choose Options Compare
Quick view Biovision | Salvianolic acid B | B3102 Salvianolic acid B is an antioxidant and anti-inflammatory compound extracted from Salvia miltiorrhiza. It shows cardioprotective and chemopreventative properties. It shows high free radical... MSRP: Was: Now: £526 - £1,606 Choose Options Compare
Quick view Biovision | Xylitol | B3101 Xylitol is a sugar alcohol derived from xylose by reduction of the carbonyl group. It is used as a food additive and sugar substitute. It is found in many fruits and vegetables. It is added to some... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | TEMPOL | B3100 TEMPOL is a piperidine nitroxide and spin label with superoxide dismutase (SOD) mimetic activity. It is a membrane permeable, free radical scavenger. It inhibits lipid peroxidation induced by iron... MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Biovision | Digoxigenin | B3099 Digoxigenin is the aglycone of digoxin. It is commonly used as a non-radioactive labeling reagent for the detection of RNA, DNA and proteins. Digoxigenin-labeled probes are used in situ hybridization... MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Biovision | ML133 Hydrochloride | B3097 ML133 is an inward-rectifier potassium channel 2 (Kir2) inhibitor. It inhibits Kir2.1 with an IC₅₀ of 1.8 μM at pH 7.4 and 290 nM at pH 8.5. It is selective for Kir2 channels over Kir1.1 and Kir4.1... MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Biovision | Lexibulin | B3096 Lexibulin is an orally available inhibitor of microtubule polymerization with an IC₅₀ of 3 µM. It blocks cell cycle at the G2-M phase, which leads to cell death. It is cytotoxic to various cell lines... MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Details Biovision | 4-Hydroxyquinazoline | B3148 MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Details Biovision | ICR-1 AM | B3147 MSRP: Was: Now: £1,460 - £2,214 Choose Options Compare
Quick view Details Biovision | Fluo-4 AM | B3146 MSRP: Was: Now: £1,100 - £1,656 Choose Options Compare
Quick view Details Biovision | IPG-4 TMA⁺ Salt | B3145 MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Details Biovision | IPG-4 AM | B3144 MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Details Biovision | IPG-2 TMA⁺ Salt | B3143 MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Details Biovision | IPG-2 AM | B3142 MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Details Biovision | IPG-1 TMA+ Salt | B3141 MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Details Biovision | IPG-1 AM | B3140 MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Details Biovision | ING-2 TMA+ Salt | B3138 MSRP: Was: Now: £1,394 - £2,116 Choose Options Compare
Quick view Details Biovision | ING-2 AM | B3137 MSRP: Was: Now: £1,558 - £2,376 Choose Options Compare
Quick view Details Biovision | Longdaysin | B3136 MSRP: Was: Now: £508 - £1,542 Choose Options Compare
Quick view Details Biovision | 4-Aminonaphthalimide | B3134 MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Details Biovision | 3-Cyano-7-ethoxycoumarin | B3133 MSRP: Was: Now: £394 - £1,082 Choose Options Compare
Quick view Details Biovision | 3,6-Dihydroxyflavone | B3132 MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Details Biovision | Penicillin G Potassium | B3131 MSRP: Was: Now: £380 - £806 Choose Options Compare
Quick view Details Biovision | 2-Guanidinobenzimidazole | B3130 MSRP: Was: Now: £364 - £904 Choose Options Compare
Quick view Details Biovision | 2-Chloroadenosine | B3129 MSRP: Was: Now: £478 - £1,410 Choose Options Compare
Quick view Details Biovision | 2-Bromopalmitic acid | B3128 MSRP: Was: Now: £364 - £836 Choose Options Compare
Quick view Details Biovision | 1,10-Phenanthroline | B3122 MSRP: Was: Now: £364 - £508 Choose Options Compare
Quick view Details Biovision | Ponesimod | B3121 MSRP: Was: Now: £560 - £1,738 Choose Options Compare
Quick view Details Biovision | Trilaciclib dihydrochloride | B3120 MSRP: Was: Now: £722 - £2,394 Choose Options Compare
Quick view Details Biovision | Fluvoxamine Maleate | B3118 MSRP: Was: Now: £364 - £934 Choose Options Compare
Quick view Details Biovision | Otenabant Hydrochloride | B3117 MSRP: Was: Now: £444 - £1,278 Choose Options Compare
Quick view Details Biovision | Perphenazine | B3115 MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Details Biovision | Tiagabine hydrochloride | B3114 MSRP: Was: Now: £364 - £934 Choose Options Compare
Quick view Details Biovision | Labetalol Hydrochloride | B3113 MSRP: Was: Now: £428 - £1,214 Choose Options Compare
Quick view Details Biovision | Metoclopramide Hydrochloride | B3112 MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Details Biovision | GGTI-298 Trifluoroacetate | B3110 MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Details Biovision | Osilodrostat | B3108 MSRP: Was: Now: £658 - £2,116 Choose Options Compare
Quick view Details Biovision | Opicapone | B3107 MSRP: Was: Now: £444 - £1,278 Choose Options Compare
Quick view Details Biovision | Ripretinib | B3106 MSRP: Was: Now: £380 - £1,018 Choose Options Compare
Quick view Details Biovision | DMSO (Anhydrous) | B3105 MSRP: Was: Now: £806 - £2,376 Choose Options Compare
Quick view Details Biovision | Salvianolic acid B | B3102 MSRP: Was: Now: £526 - £1,606 Choose Options Compare
Quick view Details Biovision | Digoxigenin | B3099 MSRP: Was: Now: £364 - £952 Choose Options Compare
Quick view Details Biovision | ML133 Hydrochloride | B3097 MSRP: Was: Now: £380 - £1,002 Choose Options Compare
Quick view Details Biovision | Lexibulin | B3096 MSRP: Was: Now: £380 - £1,018 Choose Options Compare