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Biovision Human Recombinant

  • PPP1SS, human recombinant

    Biovision | PPP1SS, human recombinant | P1182

    PPP1CC, also known as serine/threonine-protein phosphatase PP1-gamma catalytic subunit, is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. This protein is involved in...

    €1,503
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  • PPM1F, human recombinant

    Biovision | PPM1F, human recombinant | 7810

    PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus...

    €1,848
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  • PPARG, Human Recombinant

    Biovision | PPARG, Human Recombinant | P1120

    Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferators activated receptors (PPARs). Nuclear...

    €6,441
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  • PPA1, human recombinant

    Biovision | PPA1, human recombinant | 7818

    PPA1 (Pyrophosphatase) belongs to the PPase family. This protein is an enzyme that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. The hydrolysis of inorganic pyrophosphate (PPi) to two phosphate ions is utilized in many...

    €1,848
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  • PNP, human recombinant

    Biovision | PNP, human recombinant | 7831

    PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare...

    €1,848
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  • PGK2, human recombinant

    Biovision | PGK2, human recombinant | 7820

    PGK2 is a testis-specific form of phosphoglycerate kinase. Initially assumed to be a pseudogene, this protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate,...

    €2,289
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  • PGK1, human recombinant

    Biovision | PGK1, human recombinant | 7819

    Phosphoglycerate kinase 1 (PGK1) is an X-linked enzyme that plays a key role in the glycolytic pathway. The gene encoding the erythrocyte enzyme PGK1 and it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) as a...

    €1,848
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  • PDCD1LG2, human recombinant

    Biovision | PDCD1LG2, human recombinant | 7337

    Programmed cell death 1 ligand 2, also known as PDCD1LG2, is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell...

    €1,599
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  • PCNA, human recombinant

    Biovision | PCNA, human recombinant | 4835

    Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and...

    €2,091
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  • PARP-1, human recombinant

    Biovision | PARP-1, human recombinant | 4992

    Poly-ADP-ribose metabolism plays a major role in a wide range of biological processes, such as maintenance of genomic stability, transcriptional regulation, energy metabolism and apoptosis. PARP1 Enzyme, is highly purified and enzymatically active human...

    €1,995
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  • OSTF1, human recombinant

    Biovision | OSTF1, human recombinant | 7336

    Osteoclast-stimulating factor-1 (OSTF1) is an intracellular protein produced by osteoclasts that indirectly induces osteoclast (OCL) formation and bone resorption. OSTF1 is highly expressed in OCL and contains structural domains such as SH3 and ankyrin...

    €1,356
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  • Osteopontin, human recombinant

    Biovision | Osteopontin, human recombinant | 7335

    Osteopontin (OPN), also known as Secreted phosphoprotein 1 (SPP1), is a human gene product which is conserved in other species. This protein is glycoprotein that was first identified in osteoblasts and plays an important role in bone remodeling, immune...

    €1,701
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  • NME3, human recombinant

    Biovision | NME3, human recombinant | 7825

    NME3, also known as, a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the synthesis of nucleoside triphosphates and may play a role in...

    €1,848
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  • NME2, human recombinant

    Biovision | NME2, human recombinant | 7824

    NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of...

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  • NME1, human recombinant

    Biovision | NME1, human recombinant | 7823

    Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic...

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  • NAD Kinase, human recombinant

    Biovision | NAD Kinase, human recombinant | 7560

    NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to...

    €1,503
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  • MAGE-1, human recombinant

    Biovision | MAGE-1, human recombinant | 4820

    0Biovision | 4820 | MAGE-1 human recombinant DataSheetBiomolecule/Target: N/ASynonyms: Melanoma-associated antigen 1, MAGE-1 antigen, Antigen MZ2-E, Cancer/testis antigen 1,1, CT1,1, MAGEA1, MAGE1, MAGE1A, MGC9326,Alternates names: N/ATaglines: A...

    €3,174
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  • Galectin-8, Human Recombinant

    Biovision | Galectin-8, Human Recombinant | 7367

    Galectin-8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin...

    €864 - €1,701
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  • LBP, human recombinant

    Biovision | LBP, human recombinant | 4935

    Natural LBP is a 58 kDa glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNF). It acts as opsonin for GRAM negative cells, LPS, neutrophils and...

    €2,337
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  • KLRK1, human recombinant

    Biovision | KLRK1, human recombinant | 7356

    KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and...

    €1,701
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  • KLRG1, human recombinant

    Biovision | KLRG1, human recombinant | 7355

    KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and...

    €1,746
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  • KLRC3, human recombinant

    Biovision | KLRC3, human recombinant | 7354

    KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin...

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  • KLRC2, human recombinant

    Biovision | KLRC2, human recombinant | 7353

    NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural...

    €2,091
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  • KLRB1, human recombinant

    Biovision | KLRB1, human recombinant | 7352

    Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune...

    €1,701
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  • Keratin-8, human recombinant

    Biovision | Keratin-8, human recombinant | 4817

    Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas...

    €3,219
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  • IRF3, human recombinant

    Biovision | IRF3, human recombinant | 7323

    Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is...

    €1,599
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  • IRF2, human recombinant

    Biovision | IRF2, human recombinant | 7322

    Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively...

    €2,091
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  • IRF1, human recombinant

    Biovision | IRF1, human recombinant | 7321

    IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for...

    €1,701
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  • IMPAD1, human recombinant

    Biovision | IMPAD1, human recombinant | 7812

    IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations...

    €1,848
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  • IL1F10, human recombinant

    Biovision | IL1F10, human recombinant | 7325

    IL1F10 is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate...

    €1,770
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  • IL18BP, human recombinant

    Biovision | IL18BP, human recombinant | 7324

    IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein...

    €1,770
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  • IL13RA2, human recombinant

    Biovision | IL13RA2, human recombinant | 7351

    IL13RA2 is closely related to Il13RA1, a subunit of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the...

    €1,701
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  • IGF-BP6, human recombinant

    Biovision | IGF-BP6, human recombinant | 7350

    IGFBP6 contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter...

    €1,701
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  • ICAM2, human recombinant

    Biovision | ICAM2, human recombinant | 7349

    ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a...

    €1,701
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  • Human Recombinant UGDH

    Biovision | Human Recombinant UGDH | 6368

    UGDH is part of the UDP-glucose/GDP-mannose dehydrogenase family and is a widely expressed enzyme localized in the liver. UGDH transfers UDP-glucose to UDP-glucuronate and thus takes part in the biosynthesis of glycosaminoglycans such as hyaluronan,...

    €2,142
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  • Human Recombinant UCHL5

    Biovision | Human Recombinant UCHL5 | 6359

    UCHL5 is a member of the peptidase C12 family. It is a protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains, and is the deubiquitinating enzyme related to the 19S regulatory subunit of the 26S proteasome.Biovision | 6359 | Human...

    €2,091
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  • Human Recombinant UCHL3

    Biovision | Human Recombinant UCHL3 | 6358

    Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the hydrolysis of amides, esters and thioesters of the C-terminus of ubiquitin. UCH-L3 is a member of the lower molecular weight group of UCHs involved in the...

    €1,848
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  • Human Recombinant UCHL1

    Biovision | Human Recombinant UCHL1 | 6306

    PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological...

    €2,019
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  • Human recombinant UBE2L3

    Biovision | Human recombinant UBE2L3 | 6431

    UBE2L3 (UbcH7) is an E2 (ubiquitin conjugating enzyme) ligase involved in the conjugation of ubiquitin to target substrates, along with E1 and E3 enzymes. UbcH7 has been shown to work with HECT domain E3’s (E6-AP), in addition to RING containing E3’s...

    €1,674
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  • Human recombinant UBE2D3

    Biovision | Human recombinant UBE2D3 | 6430

    UBE2D3 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, having 88% and 89% sequence identity with UbcH5b...

    €1,674
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  • Human Recombinant TXNRD1

    Biovision | Human Recombinant TXNRD1 | 6330

    Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a...

    €2,091
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