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Biovision

  • BIX 01294

    Biovision | BIX 01294 | 1678

    Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of...

    €888 - €2,631
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  • Biotinyl-ASTD-FMK

    Biovision | Biotinyl-ASTD-FMK | 1985

    A biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII,...

    €1,599 - €2,751
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  • Biotin-PEG₄-NHS

    Biovision | Biotin-PEG₄-NHS | B1518

    Biotin-PEG₄-NHS is a water-soluble, pegylated reagent for simple and efficient biotin labeling of antibodies, proteins and other primary-amine containing molecules.Biotin-PEG₄-NHS is a water-soluble,...

    €960 - €3,072
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  • Biotin-NHS

    Biovision | Biotin-NHS | 2347

    Biotin-NHS is a useful reagent for biotinylation of primary amines under mild conditions (pH~6.5-8.5). Some examples of primary amines for biotinylation include lysines on the surface of proteins,...

    €546 - €21,066
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  • Biotin-LC-NHS

    Biovision | Biotin-LC-NHS | 2345

    Biotin-LC-NHS is a useful reagent for biotinylation of primary amines under alkaline conditions (pH~8-9). Some examples of primary amines for biotinylation include lysines on the surface of proteins,...

    €666 - €4,548
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  • Biotin-LC-LC-NHS

    Biovision | Biotin-LC-LC-NHS | 2346

    Biotin-LC-LC-NHS is a useful reagent for biotinylation of primary amines under mild conditions (pH~6.5-8.5). Some examples of primary amines for biotinylation include lysines on the surface of...

    €909 - €33,600
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  • Biotin-HPDP

    Biovision | Biotin-HPDP | 2329

    KEY FEATURES: • HPDP contains a dithiopyridyl group which is reactive towards sulfhydryl groups (-SH) such as in cysteine (C) side chain to form stable disulfide bond • Contains a spacer arm with a...

    €1,503 - €5,088
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  • BIIB 021

    Biovision | BIIB 021 | 2291

    A synthetic, small molecule Hsp90 inhibitor that binds competitively with geldanamycin in the ATP-binding pocket of Hsp90. In tumor cells, BIIB021 induces the degradation of Hsp90 client proteins...

    €666 - €1,848
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  • BIBX-1382

    Biovision | BIBX-1382 | 9463

    BIBX 1382 is a potent, selective, reversible and ATP-competitive inhibitor of EGFR tyrosine kinase (IC₅₀ = 3 nM); displays > 1000-fold lower potency against ErbB2 (IC₅₀ = 3.4 μM) and a range of other...

    €864 - €2,682
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  • BIBW2992 (Tovok)

    Biovision | BIBW2992 (Tovok) | 1616

    BIBW-2992 is a potent irreversible EGFR/HER2 inhibitor. The potency of BIBW-2992 on the EGFR and HER2 kinases revealed IC₅₀ values of 0.5 nM and 14 nM, respectively. BIBW-2992 is highly selective for...

    €987 - €2,805
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  • BIBS39

    Biovision | BIBS39 | B1071

    BIBS-39 is a novel, nonpeptide angiotensin II receptor antagonist that displays antihypertensive activity. In contrast to the angiotensin II receptor subtype 1 (AT1) selective drug DuP 753, BIBS-39...

    €813 - €2,484
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  • BIBF1120

    Biovision | BIBF1120 | 2167

    BIBF1120 is a triple angiokinase inhibitor. It blocks signaling through vascular endothelial growth factor receptors (VEGFR; IC₅₀ values of 13 to 34 nM), platelet-derived growth factor receptors...

    €615 - €6,600
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  • BI-2536

    Biovision | BI-2536 | 2370

    BI-2536 is a potent, selective inhibitor of polo-like kinase 1 (PLK1) (IC₅₀ = 0.83 nM). It blocks the activities of Plk2 and Plk3 to a slightly lesser extent with IC₅₀ of 3.5 nM and 9.0 nM,...

    €813 - €2,385
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  • BI 6727

    Biovision | BI 6727 | 2222

    A highly potent, selective and ATP-competitive inhibitor of polo-like kinases 1, 2 and 3 (PLK1, 2 and 3), with IC₅₀s at 0.87, 5 and 56 nM, respectively.BI 6727 is a highly potent, selective and...

    €570 - €1,503
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  • BGT226

    Biovision | BGT226 | B1719

    BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively.BGT226 (NVP-BGT226) is a novel inhibitor of class I...

    €717 - €1,599
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  • BG-45

    Biovision | BG-45 | B1866

    BG-45 is a potent HDAC class I inhibitor with selectivity for HDAC3 (IC₅₀ = 289 nM) over HDAC1, 2. BG45 does not inhibit HDAC6. BG-45 alone or in combination with bortezomib has been shown to...

    €717 - €2,091
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  • Berberine Chloride

    Biovision | Berberine Chloride | 1830

    An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic...

    €546 - €1,254
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  • Bempedoic acid

    Biovision | Bempedoic acid | B1913

    Bempedoic acid is an ATP citrate lyase (ACL) inhibitor. ACL is an enzyme involved in fatty acid and cholesterol synthesis. Bempedoic acid is a convenient, oral, once-daily LDL-C lowering drug that...

    €813 - €2,484
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  • BEC

    Biovision | BEC | 2359

    A potent, slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 µM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 µM and 30 nM at pH...

    €519 - €1,329
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  • Beauvericin

    Biovision | Beauvericin | B1246

    Beauvercin is an enniatin mycotoxin isolated from fungus Beauveria sp. It has shown cytotoxic properties against insect cells SF-9 and induces apoptosis with IC₅₀ value of 4.5 µM. It has shown to...

    €666 - €1,848
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  • BDA366

    Biovision | BDA366 | B1827

    BDA-366 is a small-molecule Bcl2-BH4 domain antagonist, that binds BH4 with high affinity and selectivity. BDA-366-Bcl2 binding induces conformational change in Bcl2 that abrogates its antiapoptotic...

    €909 - €2,901
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  • BBT-594

    Biovision | BBT-594 | B2114

    BBT-594 is a potent and selective RET and JAK2 inhibitor. It impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells. Displays potent anticancer activity.BBT-594 is a potent and...

    €909 - €2,877
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  • BAZ2-ICR

    Biovision | BAZ2-ICR | B1865

    BAZ2-ICR is a small molecule inhibitor of BAZ2A (Kd = 109 nM; IC₅₀ = 130 nM) and BAZ2B (Kd = 170 nM; IC50 = 180 nM) bromodomains. It displays 15-fold selectivity for binding BAZ2A/B over CECR2 and...

    €864 - €2,583
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  • BAY-1217389

    Biovision | BAY-1217389 | B1295

    BAY-1217389 is a potent, and selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1, TTK), with potential antineoplastic activity. Upon administration, BAY-1217389 selectively...

    €864 - €2,682
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  • BAY 85-3934

    Biovision | BAY 85-3934 | 9597

    Molidustat (BAY-85-3934) is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells without...

    €909 - €2,877
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  • BAY 80-6946

    Biovision | BAY 80-6946 | B1267

    BAY 80-6946 is a highly selective and potent pan-class I PI3K inhibitor with sub-nanomolar IC₅₀s against PI3Kα and PI3Kδ. BAY 80-6946 displays preferential inhibition (about 10-fold) of AKT...

    €1,107 - €3,666
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  • BAY 63-2521

    Biovision | BAY 63-2521 | 2644

    BAY 63-2521 is a potent activator of soluble guanylate cyclase (sGC).BAY 63-2521 is a potent activator of soluble guanylate cyclase (sGC).Biovision | 2644 | BAY 63-2521 DataSheetAlternate...

    €1,011 - €3,123
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  • BAY 57-1293

    Biovision | BAY 57-1293 | 2556

    BAY 57-1293 is a potent helicase primase inhibitor. It inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the...

    €717 - €9,600
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  • BAR-502

    Biovision | BAR-502 | B1965

    BAR-502 is a dual FXR (farnesoid X receptor) and GPBAR1 (G protein-coupled bile acid-activated receptor) agonist. BAR-502 promotes browning of white adipose tissue and reverses liver steatosis and...

    €909 - €2,877
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