Quick view Biovision | BAR-501 | B1591 BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity. It effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with an EC₅₀ of 1 μM. Exposure... MSRP: Was: Now: €909 - €2,877 Choose Options Compare
Quick view Biovision | BAPTA AM | 2242 A cell-permeable, selective chelator of intracellular calcium stores. BAPTA is105-fold greater affinity for Ca2+ than for Mg2+. Inhibits thapsigargin-induced apoptosis in rat thymocytes.BAPTA AM is a... MSRP: Was: Now: €519 - €1,209 Choose Options Compare
Quick view Biovision | BAG 956 | 2456 A potent, ATP-competitive, dual PI3K/PDK-1 inhibitor in vitro and in vivo (IC₅₀ = 56, 444, 34, 117 and 240 nM for PI3K p110-α ,β,d, γ, and PDK1 kinases, respectively). Displays anticancer properties... MSRP: Was: Now: €864 - €2,583 Choose Options Compare
Quick view Biovision | Bacitracin | B1529 Bacitracin is a peptide antibiotic and an inhibitor of peptidoglycan synthesis. Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin is used to... MSRP: Was: Now: €717 - €1,968 Choose Options Compare
Quick view Biovision | Azidothymidine | B1113 Azidothymidine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC₅₀ = 3 nM) with low cytotoxicity (CC₅₀ > 5... MSRP: Was: Now: €570 - €1,356 Choose Options Compare
Quick view Biovision | AZD-9291 mesylate | B1899 AZD9291 is a potent, selective, and irreversible, third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It inhibits EGFR phosphorylation in EGFR-bearing cells... MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Biovision | AZD-9291 | 2674 AZD-9291 is a potent, third generation, mutant-selective EGFR tyrosine kinase inhibitor. It is effective against both EGFR-TKI sensitizing and resistance T790M mutations. Displays anticancer... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AZD-8931 | 9659 AZD-8931 is a potent, ATP competitive and reversible inhibitor of EGFR (ErbB-1), Neu (ErbB-2) and ErbB-3 (the IC₅₀ values are 4 nM, 3 nM and 4 nM, respectively).AZD-8931 is a potent, ATP competitive... MSRP: Was: Now: €960 - €2,829 Choose Options Compare
Quick view Biovision | AZD8835 | B1661 AZD8835 is a potent and selective inhibitor of PI3Kδ and PI3Kα with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).AZD8835 is a potent and selective... MSRP: Was: Now: €741 - €2,217 Choose Options Compare
Quick view Biovision | AZD-8186 | B1027 AZD-8186 is a potent and selective PI3Kβ/δ inhibitor. Displays potential to reduce growth of tumors dependent on dysregulated PTEN for growth.AZD-8186 is a potent and selective PI3Kβ/δ inhibitor... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | AZD8055 | 2340 A potent, ATP-competitive inhibitor of mTOR kinase (both mTORC1 and mTORC2) with an IC₅₀ of 0.8 nM. AZD8055 displays excellent selectivity (~ 1,000-fold) against all class I PI3K isoforms and other... MSRP: Was: Now: €570 - €1,356 Choose Options Compare
Quick view Biovision | AZD-6738 | B1167 AZD6738 is a potent ATR kinase inhibitor with IC₅₀ value of 1 nM against the isolated enzyme. AZD6738 selectively inhibits ATR activity by blocking the downstream phosphorylation of the... MSRP: Was: Now: €909 - €2,682 Choose Options Compare
Quick view Biovision | AZD-6482 | B1143 AZD-6482 is a potent and selective inhibitor of PI 3-kinase β (PI 3-Kβ) (IC₅₀ values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγ and PI 3-Kα, respectively). It displays 80-fold... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | AZD6244 | 2234 Cell-permeable. A potent, highly selective and non-ATP competitive inhibitor of mitogen-activated protein kinase kinase 1/2 (MEK1/2) (IC₅₀ = 14 nM/L against purified MEK1). Displays antineoplastic... MSRP: Was: Now: €570 - €1,503 Choose Options Compare
Quick view Biovision | AZD-5582 | B2362 AZD-5582 is a potent IAP inhibitor that binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC₅₀ values of 15, 21, and 15 NM, respectively).AZD-5582 is a potent IAP inhibitor that binds... MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Biovision | AZD-5363 | B1762 AZD5363, also known as Capivasertib, is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.AZD5363, also known as Capivasertib, is a potent pan-AKT... MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Biovision | AZD-5153 | B2020 AZD-5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with a bivalent binding mode. AZD-5153 ligates two bromodomains in BRD4 simultaneously. Displays cellular and... MSRP: Was: Now: €1,209 - €3,933 Choose Options Compare
Quick view Biovision | AZD-4635 | B2012 AZD-4635 is an orally available, small molecule adenosine A2A receptor antagonist. It reverses adenosine-mediated T-cell suppression and enhances antitumor immunity.AZD-4635 is an orally available,... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | AZD-4547 | 9403 AZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways,... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AZD-3965 | B2227 AZD-3965 is a potent and selective monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM; it is 6-fold selective over MCT2 and does not inhibit MCT4 even at 10 μM. AZD 3965... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | AZD-3759 | 9609 AZD-3759 is a potent epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. AZD-3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of... MSRP: Was: Now: €909 - €2,877 Choose Options Compare
Quick view Biovision | AZD-2014 | 9449 AZD-2014 is a dual mTORC1/ mTORC2 inhibitor with potential antineoplastic activity.AZD-2014 is a dual mTORC1/ mTORC2 inhibitor with potential antineoplastic activity.Biovision | 9449 | AZD-2014... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | AZD-1981 | 9611 AZD-1981 is a potent and selective antagonist of the chemoattractant receptor-homologous expressed on Th2 lymphocytes receptor (CRTh2 or DP2) with an IC₅₀ value of 4 nM; blocks functional responses... MSRP: Was: Now: €909 - €2,877 Choose Options Compare
Quick view Biovision | AZD1480 | 2315 AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ of 1.3 nM and 0.26 nM, respectively.AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ of 1.3 nM and 0.26... MSRP: Was: Now: €519 - €1,209 Choose Options Compare
Quick view Biovision | AZD-1283 | 2838 AZD-1283 is a potent antagonist of the P2Y12 receptor. In a modified Folts model in dog, AZD-1283 dose-dependently induces increases in blood flow and inhibition of ADP-induced platelet aggregation... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AZD-0156 | B1305 AZD-0156 is an orally bioavailable Ataxia Telangiectasia Mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD-0156 targets and binds to ATM,... MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Biovision | Azamulin | 2915 Azamulin is a derivative of the antibiotic pleuromutilin. It is a highly selective inhibitor of the CYP3A family (IC50 = 0.03-0.24 μM as reported in Stresser et al., DMD, January 2004 vol. 32 no. 1... MSRP: Was: Now: €570 - €1,554 Choose Options Compare
Quick view Biovision | AZ-960 | B2065 AZ-960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM. AZ-960 induces growth arrest and apoptosis of human T-cell lymphotropic virus type 1, HTLV-1-infected T cells (MT-1... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | AZ-7371 | B2294 AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value of 10 nM. It also inhibits PDE6 (IC₅₀ = 4 µM).AZ-7371 is a non-covalent inhibitor of... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | AZ-6102 | B1200 AZ-6102 is a potent TNKS1/2 inhibitor (Tankyrase) that displays >100-fold selectivity against other poly (ADP-ribose) polymerase (PARP) family enzymes and inhibits Wnt pathway with IC₅₀ value of 5 nM... MSRP: Was: Now: €960 - €2,925 Choose Options Compare
Quick view Biovision | AZ-505 ditrifluoroacetate | B1883 AZ-505 is a potent and highly selective inhibitor of SMYD2 (IC₅₀ = 0.12 μM) with potential anticancer activity. Displays >600-fold selectivity over other histone methyltransferases, such as SMYD3... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AZ-3146 | B1145 AZ 3146 is a potent and selective Mps1 (monopolar spindle 1) kinase inhibitor (IC₅₀ = 35 nM). Shows selectivity over 46 other kinases including aurora kinase B and Cdk1. AZ 3146 overrides spindle... MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Biovision | AZ10417808 | 2786 AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced... MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Biovision | Axitinib (AG-013736) | 1581 Axitinib (also known as AG-013736) is a small molecule tyrosine kinase inhibitor. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, and cKIT (CD117). It has been shown to... MSRP: Was: Now: €888 - €1,770 Choose Options Compare
Quick view Biovision | AVL-292 (Spebrutinib) | 9413 AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC₅₀ = 0. 5 nM) with potential antineoplastic activity.AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | Avibactam sodium | 9569 Avibactam (NXL104) is a potent inhibitor of class A and C serine β-lactamases, including KPC carbapenemases. NXL104 quantitatively inhibits BlaC, the only chromosomally encoded β-lactamase from... MSRP: Was: Now: €1,158 - €3,639 Choose Options Compare
Quick view Biovision | AV-412 tosylate | B2052 AV-412 is a dual EGFR/ErbB2 kinase inhibitor with IC₅₀ values of 43 nM and 282 nM, respectively. Displays anticancer activity.AV-412 is a dual EGFR/ErbB2 kinase inhibitor with IC₅₀ values of 43 nM... MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Biovision | Aurora Kinase B Inhibitor (AZD1152-HQPA) | 1583 A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A ( Ki values of 1300 nM and 0.36 nM for aurora kinase A and B,... MSRP: Was: Now: €1,254 - €3,174 Choose Options Compare
Quick view Biovision | Aurantimycin A | 9692 Aurantimycin A is a depsipeptide antibiotic that acts as a C5a antagonist. Active against Gram-positive bacteria. Displays anti-inflammatory and nematocide activity. Also an antiulcer agent... MSRP: Was: Now: €570 - €1,503 Choose Options Compare
Quick view Biovision | AT-7519 hydrochloride | 2816 AT-7519 is a potent CDK inhibitor with potential antineoplastic activity. AT-7519 displays potent antiproliferative activity (40-940 nM) in a panel of human tumor cell lines, and the mechanism of... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AT-406 | B1829 AT-406 is a potent inhibitor of IAP (inhibitor of apoptosis protein) family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological... MSRP: Was: Now: €1,209 - €4,056 Choose Options Compare
Quick view Biovision | AT-13387 | B1961 AT-13387 is a synthetic, orally bioavailable and small-molecule inhibitor of heat shock protein 90 (Hsp90) with IC₅₀ value of 18 nM in A375 cells. Hsp90 acts as a “molecular chaperone” stabilizing... MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Biovision | AT-13148 | B1144 AT13148 is a potent, ATP-competitive multi-AGC kinase inhibitor that displays antitumor activity. AT13148 blocks AKT, p70S6K, PKA, ROCK, and SGK substrate phosphorylation inducing concentration... MSRP: Was: Now: €987 - €3,072 Choose Options Compare
Quick view Biovision | AT-101 | 2380 AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the antiapoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and an inducer of the pro-apoptotic proteins noxa and puma. It... MSRP: Was: Now: €762 - €2,313 Choose Options Compare
Quick view Biovision | AT 56 | 2592 AT-56 is a selective, competitive, and highly bioavailable inhibitor of L-PGDS (lipocalin-type prostaglandin D synthase) (Ki = 75 µM). It inhibits the production of PGD2 by L-PGDS purified from human... MSRP: Was: Now: €1,062 - €2,142 Choose Options Compare
Quick view Biovision | Aspterric acid | B2233 Aspterric acid is an antibiotic that acts as a plant growth regulator.Aspterric acid is an antibiotic that acts as a plant growth regulator.Biovision | B2233 | Aspterric acid DataSheetAlternate... MSRP: Was: Now: €1,701 - €5,631 Choose Options Compare
Quick view Biovision | ASP-3026 | B1296 ASP-3026 is a potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) with IC₅₀ value of 3.5 nM. It also inhibits ROS (IC₅₀ = 8.9 nM) and ACK (IC₅₀ = 5.8 nM)... MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Biovision | ASB-16 | 2136 A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful... MSRP: Was: Now: €693 - €1,650 Choose Options Compare
Quick view Biovision | ASB-14 | 1738 A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-14 exhibits better protein solubilization properties than CHAPS. Also useful... MSRP: Was: Now: €1,158 - €3,885 Choose Options Compare
Quick view Biovision | AS-2444697 Hydrochloride | B1585 AS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC₅₀ = 21 nM). It exhibits 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and... MSRP: Was: Now: €1,209 - €4,056 Choose Options Compare
Quick view Biovision | AS-041164 | B1870 AS-041164 is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor (IC₅₀ = 0.07, 0.24, 1.45, and 1.70 μM for the γ, α, β, and δ isoforms respectively).AS-041164 is a potent,... MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Biovision | AS 604850 | 2339 Cell-permeable. A selective, ATP-competitive inhibitor of PI3Kγ with IC50 values of 0.25, >20, >20, and 4.5 µM for the human recombinant γ, δ, β, and α isoforms, respectively. AS 604850 inhibits... MSRP: Was: Now: €546 - €1,254 Choose Options Compare
Quick view Details Biovision | Bacitracin | B1529 MSRP: Was: Now: €717 - €1,968 Choose Options Compare
Quick view Details Biovision | Azidothymidine | B1113 MSRP: Was: Now: €570 - €1,356 Choose Options Compare
Quick view Details Biovision | AZD-9291 mesylate | B1899 MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Details Biovision | AZD-8186 | B1027 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | AZD-5153 | B2020 MSRP: Was: Now: €1,209 - €3,933 Choose Options Compare
Quick view Details Biovision | AZD-4635 | B2012 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | AZ-505 ditrifluoroacetate | B1883 MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Details Biovision | AZ10417808 | 2786 MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Details Biovision | Axitinib (AG-013736) | 1581 MSRP: Was: Now: €888 - €1,770 Choose Options Compare
Quick view Details Biovision | AVL-292 (Spebrutinib) | 9413 MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Details Biovision | Avibactam sodium | 9569 MSRP: Was: Now: €1,158 - €3,639 Choose Options Compare
Quick view Details Biovision | AV-412 tosylate | B2052 MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Details Biovision | Aurora Kinase B Inhibitor (AZD1152-HQPA) | 1583 MSRP: Was: Now: €1,254 - €3,174 Choose Options Compare
Quick view Details Biovision | Aurantimycin A | 9692 MSRP: Was: Now: €570 - €1,503 Choose Options Compare
Quick view Details Biovision | AT-7519 hydrochloride | 2816 MSRP: Was: Now: €717 - €2,091 Choose Options Compare
Quick view Details Biovision | Aspterric acid | B2233 MSRP: Was: Now: €1,701 - €5,631 Choose Options Compare
Quick view Details Biovision | AS-2444697 Hydrochloride | B1585 MSRP: Was: Now: €1,209 - €4,056 Choose Options Compare
Quick view Details Biovision | AS-041164 | B1870 MSRP: Was: Now: €717 - €2,091 Choose Options Compare
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