Quick view Biovision | CEP-33779 | B2473 CEP-33779 is a potent and orally available inhibitor of JAK2 (IC₅₀ = 1.3 nM). It displays 65-fold selectivity for JAK2 over JAK3. CEP-33779 induces regression of established colorectal tumors,... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | Alvimopan | B2472 Alvimopan is a peripherally acting μ-opioid receptor antagonist (Ki = 0.47 nM) that is selective over the κ- and δ-opioid receptors (Ki's = 100 nM and 12 nM, respectively). It is used to avoid... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | dBET6 | B2471 dBET6 is a highly potent, selective and cell-permeable degrader of BET based on PROTAC, with an IC₅₀ of 14 nM. dBET6 prompts a collapse of global elongation that phenocopies CDK9 inhibition. Displays... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | PF-04965842 | B2470 PF-04965842 (Abrocitinib) is a potent, selective, orally bioavailable JAK1 inhibitor (IC₅₀ = 29 nM). It displays excellent selectivity for JAK1 versus other JAK family enzymes.PF-04965842... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | Reparixin | B2469 Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC₅₀s of 1 and 100 nM, respectively. Blocks a range of activities including leukocyte... MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Biovision | PF-3084014 | B2468 PF-3084014 (Nirogacestat) is a potent and selective gamma-secretase inhibitor (IC₅₀ of 6.2 nM). Reduces Aβ in brain, CSF and plasma in mice and guinea pigs.PF-3084014 (Nirogacestat) is a potent and... MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Biovision | PF-04449913 | B2467 PF-04449913 is a potent and orally bioavailable smoothened (SMO) inhibitor. PF-04449913 binds to human SMO with an IC₅₀ of 4 nM. It has been shown to attenuate leukemia stem cell self-renewal and... MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Biovision | Sulfatinib | B2466 Sulfatinib is a potent, orally bioavailable and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC₅₀s of in a range of 1 to 24 nM.Sulfatinib is a potent, orally... MSRP: Was: Now: €717 - €1,893 Choose Options Compare
Quick view Biovision | Amrinone | B2465 Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic... MSRP: Was: Now: €570 - €1,209 Choose Options Compare
Quick view Biovision | Lanreotide acetate | B2464 Lanreotide is a synthetic polypeptide analogue of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | Indisulam | B2463 Indisulam is a novel sulfonamide antitumor agent that displays potent antitumor activity in vitro and in vivo. It affects cell cycle progression in human tumor cells. Indisulam also acts as a... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | ARRY-797 | B2462 ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.ARRY-797 is a potent and... MSRP: Was: Now: €615 - €1,599 Choose Options Compare
Quick view Biovision | BIBF-0775 | B2461 BIBF-0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor (IC₅₀ = 34 nM).BIBF-0775 is a potent and selective transforming growth factor β (TGFβ) type I... MSRP: Was: Now: €615 - €1,599 Choose Options Compare
Quick view Biovision | PZ-2891 | B2460 PZ-2891 (PZ2891) a specific, allosteric, brain-permeable, pantothenate kinase (PANK) modulator. it acts as both an orthosteric inhibitor (IC₅₀ =1.3 nM, hPANK3) and an allosteric activator of PANK3... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | HDM-201 | B2459 Siremadlin (NVP-HDM201) is a potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell... MSRP: Was: Now: €615 - €1,503 Choose Options Compare
Quick view Biovision | Erdafitinib | B2458 Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. It inhibits FGFR1/2/3/4 with IC₅₀s of 1.2, 2... MSRP: Was: Now: €666 - €2,091 Choose Options Compare
Quick view Biovision | Garenoxacin | B2457 Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor.Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor... MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Biovision | Vitamin A | B2456 Vitamin A is an intermediate in retinol metabolism in animals. It is metabolized to retinoic acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). roles in... MSRP: Was: Now: €615 - €1,209 Choose Options Compare
Quick view Biovision | Phytol | B2455 Phytol is a diterpene alcohol commonly used as an aromatic ingredient in many fragrance compounds. Phytol and its metabolites have been reported to activate retinoid X receptors (RXRs) and to promote... MSRP: Was: Now: €570 - €1,062 Choose Options Compare
Quick view Biovision | LXR-623 | B2454 LXR-623 is a potent and selective LXR (liver X receptor) agonist. Reduces total serum cholesterol and LDL cholesterol, and inhibits lesion growth in models of atherosclerosis. Increases ABCA1 and... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | BTK Inhibitor II | B2453 BTK inhibitor II is a potent Bruton's tyrosine kinase (BTK) inhibitor.BTK inhibitor II is a potent Bruton's tyrosine kinase (BTK) inhibitor.Biovision | B2453 | BTK Inhibitor II DataSheetAlternate... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | GSK-626616 | B2452 GSK-626616 is a potent and selective DYRK inhibitor (IC₅₀ = 0.7 nM); inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency. Displays ~20-fold selectivity over casein... MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Biovision | Trypsin Substrate (Colorimetric) | B2451 A chromogenic trypsin substrate. Trypsin cleaves p-nitroanilide (pNA) releasing p-nitroanilne that can be quantified using a spectrophotometer or a microtiter plate reader at ~ 405 nm.Ac-GPK-pNA is a... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | KL001 | B2449 KL001 is a cryptochrome protein (CRY) stabilizer. It blocks ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. Represses glucagon-induced hepatic... MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Biovision | Carmofur | B2448 Carmofur is derivative of 5-flurouracil (Cat. No. B1519) that acts as an inhibitor of acid ceramidase (IC₅₀ = 79 nM for the rat enzyme). It reduces acid ceramidase activity in a dose- and... MSRP: Was: Now: €570 - €1,209 Choose Options Compare
Quick view Biovision | Carglumic acid | B2447 Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a... MSRP: Was: Now: €519 - €1,062 Choose Options Compare
Quick view Biovision | Anagrelide | B2446 Anagrelide is a phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 36 nM) with antiplatelet activity. Anagrelide inhibits the maturation of megakaryocytes into platelets, reducing both megakaryocyte... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | Amsacrine | B2445 Amsacrine is a potent DNA intercalating and an antineoplastic agent. One of the ways amsacrine works is by blocking an enzyme topoisomerase 2. It is effective in the treatment of acute leukemias and... MSRP: Was: Now: €615 - €1,356 Choose Options Compare
Quick view Biovision | Altretamine | B2444 Altretamine is an alkylating agent with antineoplastic and antiproliferative activity. It also acts as a chemosterilant for male houseflies and other insects.Altretamine is an alkylating agent with... MSRP: Was: Now: €570 - €1,209 Choose Options Compare
Quick view Biovision | 9-Cis-Retinoic acid | B2443 9-cis Retinoic acid is an agonist at retinoic acid receptors (RARs) and retinoic X receptors (RXRs). 9-cis Retinoic acid also inhibits adipogenesis. In lymphatic endothelial cells, 9-cis retinoic... MSRP: Was: Now: €570 - €1,107 Choose Options Compare
Quick view Biovision | Carboxyatractyloside Potassium salt | B2442 Carboxyatractyloside is a plant-derived natural heteroglucoside that prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and... MSRP: Was: Now: €666 - €1,209 Choose Options Compare
Quick view Biovision | Atractyloside Potassium salt | B2441 Atractyloside is an extremely toxic glycoside isolated from thistles. It blocks mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di-... MSRP: Was: Now: €864 - €1,158 Choose Options Compare
Quick view Biovision | Atuveciclib | B2440 Atuveciclib (BAY-1143572) is a potent and selective CDK9/P-TEFb inhibitor (IC₅₀ = 6 nM for CDK9/CyclinT1); displays >150-fold selectivity over CDK1/2/3/5/6/7 (IC₅₀ >800 nM). Exhibits anticancer... MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Biovision | Tenalisib | B2439 Tenalisib is a potent, and selective PI3Kδ and PI3Kγ inhibitor with IC₅₀ values of 25 and 33 nM, respectively. Displays good selectivity over p110α (>300-fold) and p110β (>100-fold) isoforms... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | INCB057643 | B2438 INCB057643 is a potent and selective BET inhibitor; displays more effectivity against androgen-dependent (VCaP and LNCaP) than androgen-independent (DU145 and PC3) cells with IC50 of 500 nM,... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | Adavivint | B2437 Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker... MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Biovision | IDF-11774 | B2436 IDF-11774 is a potent hypoxia-inducible factor (HIF)-1 inhibitor (IC₅₀ = 3.65 μM)IDF-11774 is a potent hypoxia-inducible factor (HIF)-1 inhibitor (IC₅₀ = 3.65 μM)Biovision | B2436 | IDF-11774... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | Leniolisib | B2435 Leniolisib is a potent and selective PI3Kδ inhibitor with an IC₀ of 11 nM; displays >20-fold, 40-fold, and 200-fold selectivity over PI3Kα, PI3Kβ, and PI3Kγ, respectively; shows 30-fold cellular... MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Biovision | EX-229 | B2434 EX-229 is a potent and allosteric activator of AMP-activated protein kinase (AMPK). In rat epitrochlearis muscle, ex229 dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing... MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Biovision | EBI-2511 | B2433 EBI-2511 is a highly potent and orally active EZH2 inhibitor with an IC₅₀ of 4 nM for EZH2(A667G). EBI-2511 displays excellent in vivo efficacy in Pfeiffer tumor Xenograft models in mouse and could... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | LIT-927 | B2432 LIT-927 is a locally and orally active CXCL12 neutraligand (Ki = 267 nM for CXCL12-TR binding). Displays anti-inflammatory effect in a murine model of allergic airway hypereosinophilia.LIT-927 is a... MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Biovision | MK-3903 | B2431 MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator (EC₅₀ = 8 nM).MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator (EC₅₀ = 8 nM).Biovision |... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | HS-1371 | B2430 HS-1371 is a potent RIP3 kinase inhibitor (IC₅₀ = 20.8 nM). It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro. . It inhibits TNF-induced... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | TH-34 | B2429 TH-34 is a HDAC inhibitor that displays selectivity for HDACs 6, 8 and 10 over HDACs 1, 2 and 3. TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.TH-34 is a... MSRP: Was: Now: €909 - €2,877 Choose Options Compare
Quick view Biovision | Rilpivirine hydrochloride | B2427 Rilpivirine hydrochloride is a diarylpyrimidine derivative that acts as a reverse transcriptase inhibitor with antiviral activity against HIV-1. Rilpivirine is associated with a low rate of transient... MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Biovision | GSK-2814338 | B2426 GSK-2814338 is a potent Lp-PLA2 inhibitor useful for the treatment of atherosclerosis and Alzheimer's diseaseGSK-2814338 is a potent Lp-PLA2 inhibitor useful for the treatment of atherosclerosis and... MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Biovision | GSK-269962 hydrochloride | B2425 GSK-269962 is a potent and selective Rho kinase (ROCK) inhibitor (IC₅₀ values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). It displays >30-fold selectivity for ROCK against a... MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Biovision | BIIE 0246 | B2424 BIIE 0246 is a potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y2 receptor (IC₅₀ = 15 nM). BIIE 0246 displays > 650-fold selectivity over Y1, Y4 and Y5 receptors.BIIE... MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Biovision | Terbinafine (Free base) | B2423 Terbinafine is an allylamine antifungal agent that acts as a squalene epoxidase inhibitor.Terbinafine is an allylamine antifungal agent that acts as a squalene epoxidase inhibitor.Biovision | B2423 |... MSRP: Was: Now: €570 - €960 Choose Options Compare
Quick view Biovision | Naftifine hydrochloride | B2422 Naftifine hydrochloride is an allylamine compound that displays antifungal and antimycotic activities. It inhibits fungal squalene epoxidase and prevents ergosterol biosynthesis. Naftifine also shows... MSRP: Was: Now: €615 - €1,599 Choose Options Compare
Quick view Biovision | Butenafine hydrochloride | B2421 Butenafine is a potent antifungal agent that has broad-spectrum activity against 87 strains of dermatophytes. Butenafine works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase,... MSRP: Was: Now: €570 - €1,503 Choose Options Compare
Quick view Biovision | BMS-986142 | B2420 BMS-986142 is a potent, selective, and reversible BTK (Bruton’s tyrosine kinase) inhibitor (BTK IC₅₀ = 0.5nM; human WB IC₅₀ = 90 nM). BMS-986142 displays robust efficacy in murine models of... MSRP: Was: Now: €909 - €2,877 Choose Options Compare
Quick view Details Biovision | CEP-33779 | B2473 MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Details Biovision | Alvimopan | B2472 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | PF-04965842 | B2470 MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Details Biovision | Reparixin | B2469 MSRP: Was: Now: €864 - €2,682 Choose Options Compare
Quick view Details Biovision | PF-3084014 | B2468 MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Details Biovision | PF-04449913 | B2467 MSRP: Was: Now: €615 - €1,701 Choose Options Compare
Quick view Details Biovision | Sulfatinib | B2466 MSRP: Was: Now: €717 - €1,893 Choose Options Compare
Quick view Details Biovision | Lanreotide acetate | B2464 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | Indisulam | B2463 MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Details Biovision | BIBF-0775 | B2461 MSRP: Was: Now: €615 - €1,599 Choose Options Compare
Quick view Details Biovision | Erdafitinib | B2458 MSRP: Was: Now: €666 - €2,091 Choose Options Compare
Quick view Details Biovision | Garenoxacin | B2457 MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Details Biovision | Vitamin A | B2456 MSRP: Was: Now: €615 - €1,209 Choose Options Compare
Quick view Details Biovision | BTK Inhibitor II | B2453 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | GSK-626616 | B2452 MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Details Biovision | Trypsin Substrate (Colorimetric) | B2451 MSRP: Was: Now: €1,062 - €3,444 Choose Options Compare
Quick view Details Biovision | Carglumic acid | B2447 MSRP: Was: Now: €519 - €1,062 Choose Options Compare
Quick view Details Biovision | Anagrelide | B2446 MSRP: Was: Now: €813 - €2,484 Choose Options Compare
Quick view Details Biovision | Amsacrine | B2445 MSRP: Was: Now: €615 - €1,356 Choose Options Compare
Quick view Details Biovision | Altretamine | B2444 MSRP: Was: Now: €570 - €1,209 Choose Options Compare
Quick view Details Biovision | 9-Cis-Retinoic acid | B2443 MSRP: Was: Now: €570 - €1,107 Choose Options Compare
Quick view Details Biovision | Carboxyatractyloside Potassium salt | B2442 MSRP: Was: Now: €666 - €1,209 Choose Options Compare
Quick view Details Biovision | Atractyloside Potassium salt | B2441 MSRP: Was: Now: €864 - €1,158 Choose Options Compare
Quick view Details Biovision | Atuveciclib | B2440 MSRP: Was: Now: €1,107 - €3,666 Choose Options Compare
Quick view Details Biovision | Tenalisib | B2439 MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Details Biovision | INCB057643 | B2438 MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Details Biovision | Adavivint | B2437 MSRP: Was: Now: €813 - €2,337 Choose Options Compare
Quick view Details Biovision | IDF-11774 | B2436 MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Details Biovision | Leniolisib | B2435 MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Details Biovision | Rilpivirine hydrochloride | B2427 MSRP: Was: Now: €666 - €1,893 Choose Options Compare
Quick view Details Biovision | GSK-2814338 | B2426 MSRP: Was: Now: €960 - €3,072 Choose Options Compare
Quick view Details Biovision | GSK-269962 hydrochloride | B2425 MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Details Biovision | BIIE 0246 | B2424 MSRP: Was: Now: €1,011 - €3,174 Choose Options Compare
Quick view Details Biovision | Terbinafine (Free base) | B2423 MSRP: Was: Now: €570 - €960 Choose Options Compare
Quick view Details Biovision | Naftifine hydrochloride | B2422 MSRP: Was: Now: €615 - €1,599 Choose Options Compare
Quick view Details Biovision | Butenafine hydrochloride | B2421 MSRP: Was: Now: €570 - €1,503 Choose Options Compare
Quick view Details Biovision | BMS-986142 | B2420 MSRP: Was: Now: €909 - €2,877 Choose Options Compare
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