Biovision

Quick view

Biovision | Furamidine dihydrochloride | B2581

Furamidine dihydrochloride is a potent, selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor (IC₅₀ = 9.4 μM). Displays selectivity over PRMT5, PRMT6 and CARM1 (IC50...

MSRP:

Was:

Now: €813 - €2,484

Choose Options Compare
Quick view

Biovision | Liraglutide | B2580

Liraglutide is a highly potent, long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC₅₀ = 61 pM). It increases cAMP accumulation in CHO cells expressing the human GLP-1 receptor. Inhibits...

MSRP:

Was:

Now: €960 - €3,072

Choose Options Compare
Quick view

Biovision | 6-Bromoisatin | B2579

6-Bromoisatin (6Br) acts as a chemopreventive compound. 6Br was found to be an effective chemo-preventative compound when orally administered in a 14-week colorectal cancer model.6-Bromoisatin (6Br)...

MSRP:

Was:

Now: €570 - €864

Choose Options Compare
Quick view

Biovision | Digitoxin | B2578

Digitoxin is a lipid soluble cardiac glycoside that acts as an inhibitor of plasma membrane Na+/K+-ATPase (EC₅₀ = 0.78 µM). Digitoxin shows a significantly cytotoxic effect in H1975 cells by causing...

MSRP:

Was:

Now: €615 - €1,554

Choose Options Compare
Quick view

Biovision | Lanatoside C | B2577

Lanatoside C is a cardiac glycoside, used in the treatment of congestive heart failure and cardiac arrhythmia. Lanatoside C suppresses colorectal cancer cell growth by inducing mitochondrial...

MSRP:

Was:

Now: €666 - €1,701

Choose Options Compare
Quick view

Biovision | BT-13 | B2576

BT-13 is a potent and selective agonist of RET tyrosine kinase and its downstream signaling cascades. BT-13 promotes neurite growth from sensory neurons in vitro and attenuates experimental...

MSRP:

Was:

Now: €615 - €1,599

Choose Options Compare
Quick view

Biovision | MS023 | B2575

MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) (IC₅₀s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8,...

MSRP:

Was:

Now: €909 - €2,877

Choose Options Compare
Quick view

Biovision | Ataciguat | B2574

Ataciguat is an anthranilic acid derivative that activates the oxidized (heme-free) form of soluble guanylate cyclase (sGC) (EC₅₀= 0.5-10 µM in purified bovine lung or crude human corpus cavernosum...

MSRP:

Was:

Now: €666 - €1,701

Choose Options Compare
Quick view

Biovision | 8-Azaadenosine | B2572

8-Azaadenosine is an ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | AZ-304 | B2571

AZ-304 is a potent, ATP-competitive dual BRAF kinase inhibitor that inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC₅₀s of 79 nM, 38 nM and 68 nM, respectively. In addition,...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | ARN-272 | B2570

ARN-272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC₅₀ = 1.8 µM). It attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Displays analgesic effects...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | AM-92016 Hydrochloride | B2569

AM-92016 hydrochloride is a specific inhibitor of delayed rectifier potassium current. In guinea-pig and rabbit ventricular cells, AM 92016 significantly increased action potential duration with 20%...

MSRP:

Was:

Now: €909 - €2,877

Choose Options Compare
Quick view

Biovision | Atractylenolide I | B2568

Atractylenolide I is a sesquiterpene that displays diverse biological activities, including anti-inflammatory, anti-angiogenic, anti-tumor, and antidepressant properties. It inhibits LPS-induced...

MSRP:

Was:

Now: €1,062 - €3,444

Choose Options Compare
Quick view

Biovision | Riviciclib hydrochloride | B2567

Riviciclib hydrochloride is a potent cyclin dependent kinase (CDK) inhibitor (IC₅₀ values of 79 nM, 63 nM and 20 nM for CDK1, CDK4 and CDK9, respectively). Displays potential antineoplastic activity...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | Sardomozide Hydrochloride | B2566

Sardomozide Hydrochloride is a second-generation polyamine synthesis inhibitor, that inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC). Sardomozide...

MSRP:

Was:

Now: €909 - €2,877

Choose Options Compare
Quick view

Biovision | TTP-22 | B2565

TTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these...

MSRP:

Was:

Now: €615 - €1,599

Choose Options Compare
Quick view

Biovision | BAY-8002 | B2564

BAY-8002 is a potent dual MCT1/2 (Monocarboxylate Transporter ½) inhibitor. Inhibits cellular SNARF-5 fluorescence change (IC₅₀ = 85 nM) in MCT1-expressing DLD-1 cells. Arrests growth and increases...

MSRP:

Was:

Now: €909 - €2,877

Choose Options Compare
Quick view

Biovision | V-9302 | B2563

V-9302 is a competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC₅₀ = 9.6 µM)...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | iCRT14 | B2562

iCRT14 is a potent potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC₅₀ = 40.3 nM). It inhibits the interaction between...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | Glumetinib | B2561

Glumetinib (SCC-244) is a potent and highly selective inhibitor of c-Met kinase (IC₅₀ = 0.42 nM). Glumetinib displays subnanomolar potency against c-Met kinase activity and high selectivity versus...

MSRP:

Was:

Now: €909 - €2,877

Choose Options Compare
Quick view

Biovision | Robenidine hydrochloride | B2560

Robenidine hydrochloride is an antibiotic used as an effective anticoccidial. It does not affect the earliest stages in the coccidial life-cycle and its main activity is against the almost mature...

MSRP:

Was:

Now: €615 - €1,209

Choose Options Compare
Quick view

Biovision | GW-311616A | B2559

GW-311616 hydrochloride is a potent and selective intracellular neutrophil elastase (NE, α-1-proteinase) inhibitor. Inhibits human neutrophil elastase (HNE) and is selective over other human serine...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | AMG-510 | B2558

AMG-510 is an orally available agent that targets the specific KRAS mutation, p.G12C, with potential antineoplastic activity. Upon oral administration, KRAS mutant-targeting AMG-510 selectively...

MSRP:

Was:

Now: €615 - €1,599

Choose Options Compare
Quick view

Biovision | (+)-cis-Diltiazem hydrochloride | B2557

(+)-cis-Diltiazem hydrochloride is an antihypertensive and cardioprotective agent and an inhibitor of L-type Ca²⁺ channels.(+)-cis-Diltiazem hydrochloride is an antihypertensive and cardioprotective...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | Tirabrutinib hydrochloride | B2556

Tirabrutinib (ONO-4059) hydrochloride is a potent and selective BTK (Bruton’s Tyrosine Kinase) inhibitor (IC₅₀ = 2.2 nm). Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | Vesatolimod | B2555

Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7) agonist which has been developed as an anti-hepatitis B virus (HBV) agent.Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7)...

MSRP:

Was:

Now: €813 - €2,484

Choose Options Compare
Quick view

Biovision | CB-1158 dihydrochloride | B2554

CB-1158 dihydrochloride (INCB01158 dihydrochloride) is a potent nhibitor of arginase, with IC₅₀s of 86 and 296 nM for recombinant human arginase 1 and 2, respectively.CB-1158 dihydrochloride...

MSRP:

Was:

Now: €813 - €2,484

Choose Options Compare
Quick view

Biovision | Dabigatran Etexilate | B2552

Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. Dabigatran selectively and reversibly inhibits human thrombin (Ki = 4.5 nM) as well as...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | L-Propargylglycine | B2551

L-Propargylglycine (PAG) is an inhibitor of cystathionine γ-lyase (CSE). Cystathionine γ-lyase catalyzes H2S synthesis and is a potential target for modulating H2S levels under pathophysiological...

MSRP:

Was:

Now: €717 - €1,701

Choose Options Compare
Quick view

Biovision | nor-NOHA acetate | B2550

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more...

MSRP:

Was:

Now: €1,158 - €3,813

Choose Options Compare
Quick view

Biovision | PF-04620110 | B2549

PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) inhibitor with (IC₅₀ = 19 nM).PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1...

MSRP:

Was:

Now: €813 - €2,484

Choose Options Compare
Quick view

Biovision | BLU-667 (Pralsetinib) | B2548

BLU-667 (Pralsetinib) is a highly potent and selective, next generation RET inhibitor with IC₅₀ of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion. In vivo, BLU-667...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | RU-521 | B2547

RU-521 (RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor (Kd = 36.2 nM). RU-521 is active and selective in cellular assays of cyclic GMP-AMP synthase-mediated signaling and...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | KKL-35 | B2546

KKL-35 is a potent trans-translation inhibitor that displays broad-spectrum antibiotic activity. KKL-35 inhibits trans-translation, and subsequent cell growth in a broad spectrum of bacterial strains...

MSRP:

Was:

Now: €960 - €3,072

Choose Options Compare
Quick view

Biovision | LOXO-101 sulfate | B2545

LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC₅₀s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other...

MSRP:

Was:

Now: €909 - €1,893

Choose Options Compare
Quick view

Biovision | Cysmethynil | B2544

Cysmethynil is a potent, time-dependent inhibitor of Icmt (IC₅₀=

MSRP:

Was:

Now: €1,107 - €3,666

Choose Options Compare
Quick view

Biovision | CBR-5884 | B2543

CBR-5884 is a potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) (IC₅₀ = 33 μM) inhibiting serine synthesis from 3-phosphoglycerate in cells. CBR-5884 inhibits serine...

MSRP:

Was:

Now: €1,062 - €3,444

Choose Options Compare
Quick view

Biovision | SBI-115 | B2542

SBI-115 is a potent TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.SBI-115 is a potent TGR5 (GPCR19) antagonist. SBI-115 decreases...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | CY-09 | B2541

CY-09 is a potent and specific NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation.CY-09 is a potent and...

MSRP:

Was:

Now: €615 - €1,554

Choose Options Compare
Quick view

Biovision | Glesatinib | B2540

Glesatinib is a potent multitargeted tyrosine kinase inhibitor. It binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte...

MSRP:

Was:

Now: €1,158 - €3,858

Choose Options Compare
Quick view

Biovision | Sitravatinib | B2539

Sitravatinib (MGCD516; MG516) is a potent receptor tyrosine kinase (RTK) inhibitor with IC₅₀s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2,...

MSRP:

Was:

Now: €813 - €1,893

Choose Options Compare
Quick view

Biovision | USP7/USP47 Inhibitor | B2538

USP7/USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC₅₀s = 0.42 and 1 μM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21,...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | Massonianoside B | B2537

Massonianoside B (MA) is a structurally unique natural product inhibitor of DOT1L with an IC50 value of 399 nM. It displays high selectivity for DOT1L over other S-adenosylmethionine (SAM)-dependent...

MSRP:

Was:

Now: €1,158 - €1,848

Choose Options Compare
Quick view

Biovision | Fadrozole | B2536

Fadrozole is a potent, nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and...

MSRP:

Was:

Now: €717 - €2,091

Choose Options Compare
Quick view

Biovision | Cabotegravir | B2535

Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity against a broad range of HIV subtypes.Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity...

MSRP:

Was:

Now: €615 - €1,356

Choose Options Compare
Quick view

Biovision | Balovaptan | B2534

Balovaptan is a potent and selective vasopressin-1 receptor antagonistBalovaptan is a potent and selective vasopressin-1 receptor antagonistBiovision | B2534 | Balovaptan DataSheetAlternate...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | GNE-272 | B2533

GNE-272 is a potent and selective in vivo probe for the bromodomains of CBP/EP300 (IC₅₀ values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively). Displays marked antiproliferative effect...

MSRP:

Was:

Now: €666 - €1,893

Choose Options Compare
Quick view

Biovision | Muramyl Dipeptide | B2532

Muramyl dipeptide is a synthetic immunoreactive peptide that activates NOD2 receptors. Induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes. Also inhibits HIV...

MSRP:

Was:

Now: €615 - €1,701

Choose Options Compare
Quick view

Biovision | CP-424174 | B2531

CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits...

MSRP:

Was:

Now: €615 - €1,554

Choose Options Compare
Quick view

Biovision | EZSolution™ INF39 | B2530

INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells.INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It...

MSRP:

Now: €864
Add to Cart Compare
Quick view

Biovision | NLRP3i | B2529

NLRP3i is an intermediate in the glyburide synthesis that acts as a NLRP3 inflammasome inhibitor. It inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size...

MSRP:

Was:

Now: €813 - €2,190

Choose Options Compare
Quick view

Biovision | STF-083010 | B2528

STF-083010 is a potent Ire1 inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. It blocks endogenous XBP1 mRNA...

MSRP:

Was:

Now: €813 - €2,337

Choose Options Compare