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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Amrinone

    Biovision | Amrinone | B2465

    Amrinone is a potent phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. It also displays positive inotropic...

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  • Lanreotide acetate

    Biovision | Lanreotide acetate | B2464

    Lanreotide is a synthetic polypeptide analogue of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other...

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  • Indisulam

    Biovision | Indisulam | B2463

    Indisulam is a novel sulfonamide antitumor agent that displays potent antitumor activity in vitro and in vivo. It affects cell cycle progression in human tumor cells. Indisulam also acts as a...

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  • ARRY-797

    Biovision | ARRY-797 | B2462

    ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.ARRY-797 is a potent and...

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  • BIBF-0775

    Biovision | BIBF-0775 | B2461

    BIBF-0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor (IC₅₀ = 34 nM).BIBF-0775 is a potent and selective transforming growth factor β (TGFβ) type I...

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  • PZ-2891

    Biovision | PZ-2891 | B2460

    PZ-2891 (PZ2891) a specific, allosteric, brain-permeable, pantothenate kinase (PANK) modulator. it acts as both an orthosteric inhibitor (IC₅₀ =1.3 nM, hPANK3) and an allosteric activator of PANK3...

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  • HDM-201

    Biovision | HDM-201 | B2459

    Siremadlin (NVP-HDM201) is a potent and highly specific MDM-2/p53 inhibitor. It binds to human MDM2 protein with a picomolar Ki value (0.21 nM). It activates p53 and induces robust p53-dependent cell...

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  • Erdafitinib

    Biovision | Erdafitinib | B2458

    Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. It inhibits FGFR1/2/3/4 with IC₅₀s of 1.2, 2...

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  • Garenoxacin

    Biovision | Garenoxacin | B2457

    Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor.Garenoxacin is a potent des-F(6)-quinolone antibacterial agent and a topoisomerase II inhibitor...

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  • Vitamin A

    Biovision | Vitamin A | B2456

    Vitamin A is an intermediate in retinol metabolism in animals. It is metabolized to retinoic acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). roles in...

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  • Phytol

    Biovision | Phytol | B2455

    Phytol is a diterpene alcohol commonly used as an aromatic ingredient in many fragrance compounds. Phytol and its metabolites have been reported to activate retinoid X receptors (RXRs) and to promote...

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  • LXR-623

    Biovision | LXR-623 | B2454

    LXR-623 is a potent and selective LXR (liver X receptor) agonist. Reduces total serum cholesterol and LDL cholesterol, and inhibits lesion growth in models of atherosclerosis. Increases ABCA1 and...

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  • BTK Inhibitor II

    Biovision | BTK Inhibitor II | B2453

    BTK inhibitor II is a potent Bruton's tyrosine kinase (BTK) inhibitor.BTK inhibitor II is a potent Bruton's tyrosine kinase (BTK) inhibitor.Biovision | B2453 | BTK Inhibitor II DataSheetAlternate...

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  • GSK-626616

    Biovision | GSK-626616 | B2452

    GSK-626616 is a potent and selective DYRK inhibitor (IC₅₀ = 0.7 nM); inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency. Displays ~20-fold selectivity over casein...

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  • KL001

    Biovision | KL001 | B2449

    KL001 is a cryptochrome protein (CRY) stabilizer. It blocks ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. Represses glucagon-induced hepatic...

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  • Carmofur

    Biovision | Carmofur | B2448

    Carmofur is derivative of 5-flurouracil (Cat. No. B1519) that acts as an inhibitor of acid ceramidase (IC₅₀ = 79 nM for the rat enzyme). It reduces acid ceramidase activity in a dose- and...

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  • Carglumic acid

    Biovision | Carglumic acid | B2447

    Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a...

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  • Anagrelide

    Biovision | Anagrelide | B2446

    Anagrelide is a phosphodiesterase 3 (PDE3) inhibitor (IC₅₀ = 36 nM) with antiplatelet activity. Anagrelide inhibits the maturation of megakaryocytes into platelets, reducing both megakaryocyte...

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  • Amsacrine

    Biovision | Amsacrine | B2445

    Amsacrine is a potent DNA intercalating and an antineoplastic agent. One of the ways amsacrine works is by blocking an enzyme topoisomerase 2. It is effective in the treatment of acute leukemias and...

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  • Altretamine

    Biovision | Altretamine | B2444

    Altretamine is an alkylating agent with antineoplastic and antiproliferative activity. It also acts as a chemosterilant for male houseflies and other insects.Altretamine is an alkylating agent with...

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  • Atuveciclib

    Biovision | Atuveciclib | B2440

    Atuveciclib (BAY-1143572) is a potent and selective CDK9/P-TEFb inhibitor (IC₅₀ = 6 nM for CDK9/CyclinT1); displays >150-fold selectivity over CDK1/2/3/5/6/7 (IC₅₀ >800 nM). Exhibits anticancer...

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  • Tenalisib

    Biovision | Tenalisib | B2439

    Tenalisib is a potent, and selective PI3Kδ and PI3Kγ inhibitor with IC₅₀ values of 25 and 33 nM, respectively. Displays good selectivity over p110α (>300-fold) and p110β (>100-fold) isoforms...

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  • INCB057643

    Biovision | INCB057643 | B2438

    INCB057643 is a potent and selective BET inhibitor; displays more effectivity against androgen-dependent (VCaP and LNCaP) than androgen-independent (DU145 and PC3) cells with IC50 of <100 nM and >500...

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  • Adavivint

    Biovision | Adavivint | B2437

    Adavivint is a potent and selective Wnt pathway inhibitor with an EC₅₀ of 3 nM in vitro; induces hMSC differentiation into mature, functional chondrocytes and decreases cartilage catabolic marker...

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  • IDF-11774

    Biovision | IDF-11774 | B2436

    IDF-11774 is a potent hypoxia-inducible factor (HIF)-1 inhibitor (IC₅₀ = 3.65 μM)IDF-11774 is a potent hypoxia-inducible factor (HIF)-1 inhibitor (IC₅₀ = 3.65 μM)Biovision | B2436 | IDF-11774...

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  • Leniolisib

    Biovision | Leniolisib | B2435

    Leniolisib is a potent and selective PI3Kδ inhibitor with an IC₀ of 11 nM; displays >20-fold, 40-fold, and 200-fold selectivity over PI3Kα, PI3Kβ, and PI3Kγ, respectively; shows 30-fold cellular...

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  • EX-229

    Biovision | EX-229 | B2434

    EX-229 is a potent and allosteric activator of AMP-activated protein kinase (AMPK). In rat epitrochlearis muscle, ex229 dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing...

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  • EBI-2511

    Biovision | EBI-2511 | B2433

    EBI-2511 is a highly potent and orally active EZH2 inhibitor with an IC₅₀ of 4 nM for EZH2(A667G). EBI-2511 displays excellent in vivo efficacy in Pfeiffer tumor Xenograft models in mouse and could...

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  • LIT-927

    Biovision | LIT-927 | B2432

    LIT-927 is a locally and orally active CXCL12 neutraligand (Ki = 267 nM for CXCL12-TR binding). Displays anti-inflammatory effect in a murine model of allergic airway hypereosinophilia.LIT-927 is a...

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  • MK-3903

    Biovision | MK-3903 | B2431

    MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator (EC₅₀ = 8 nM).MK-3903 is a potent and selective AMP-activated protein kinase (AMPK) activator (EC₅₀ = 8 nM).Biovision |...

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  • HS-1371

    Biovision | HS-1371 | B2430

    HS-1371 is a potent RIP3 kinase inhibitor (IC₅₀ = 20.8 nM). It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro. . It inhibits TNF-induced...

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  • TH-34

    Biovision | TH-34 | B2429

    TH-34 is a HDAC inhibitor that displays selectivity for HDACs 6, 8 and 10 over HDACs 1, 2 and 3. TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.TH-34 is a...

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  • GSK-2814338

    Biovision | GSK-2814338 | B2426

    GSK-2814338 is a potent Lp-PLA2 inhibitor useful for the treatment of atherosclerosis and Alzheimer's diseaseGSK-2814338 is a potent Lp-PLA2 inhibitor useful for the treatment of atherosclerosis and...

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  • BIIE 0246

    Biovision | BIIE 0246 | B2424

    BIIE 0246 is a potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y2 receptor (IC₅₀ = 15 nM). BIIE 0246 displays > 650-fold selectivity over Y1, Y4 and Y5 receptors.BIIE...

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  • BMS-986142

    Biovision | BMS-986142 | B2420

    BMS-986142 is a potent, selective, and reversible BTK (Bruton’s tyrosine kinase) inhibitor (BTK IC₅₀ = 0.5nM; human WB IC₅₀ = 90 nM). BMS-986142 displays robust efficacy in murine models of...

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  • CC-90003

    Biovision | CC-90003 | B2419

    CC-90003 is a potent extracellular signal-regulated kinases (ERK1/2) inhibitor. CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results...

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  • WM-1119

    Biovision | WM-1119 | B2418

    WM-1119 is a potent, reversible, and competitive inhibitor of lysine acetyltransferase KAT6A ( Kd = 2 nM). Displays 1,100-fold and 250-fold selectivity over KAT5 and KAT7, respectively; causes cell...

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  • Silvestrol

    Biovision | Silvestrol | B2417

    Silvestrol is a natural product isolated from the fruits and twigs of Aglaia foveolata. Acts as a eukaryotic translation initiation factor 4A (eIF4A) inhibitor. Also displays broad-spectrum antiviral...

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  • DTT

    Biovision | DTT | B2409

    A useful reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE.DTT is a...

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  • LOXO-195

    Biovision | LOXO-195 | B2226

    LOXO-195 is a potent and selective TRK (tropomyosin-related-kinase) inhibitor, with potential anticancer activity. LOXO-195 specifically targets and binds to TRK, including the fusion proteins...

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  • Dalbavancin

    Biovision | Dalbavancin | B2099

    Dalbavancin is a second-generation lipoglycopeptide antibiotic that is active against gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), and minimum inhibitory...

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  • GSK-1838705A

    Biovision | GSK-1838705A | B2026

    GSK-1838705A is a potent small-molecule kinase inhibitor that inhibits IGF-IR and IR (insulin receptor) with IC₅₀s of 2.0 and 1.6 nM, respectively. It also inhibits anaplastic lymphoma kinase (ALK)...

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