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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Ipragliflozin

    Biovision | Ipragliflozin | B1926

    Ipragliflozin is a potent inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC₅₀ = 7.4 nM for human SGLT2 in vitro) that increases excretion of glucose.Iipragliflozin is found to promote preferential loss of fat mass in a rat model of non-obese type 2...

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  • A-1210477

    Biovision | A-1210477 | B1826

    A-1210477 is a potent MCL-1 inhibitor (Ki = 0.45 nM in TR-FRET-binding assays). Acts as a weak inhibitor of BCL-2 (Ki = 0.132 μM) and BCL-XL(Ki>0.660 μM).A-1210477 is a potent MCL-1 inhibitor (Ki = 0.45 nM in TR-FRET-binding assays). Acts as a weak...

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  • PKI-402

    Biovision | PKI-402 | B1727

    PKI-402 is a potent dual inhibitor of PI3K/mTOR with IC50 values of 2 nM/7 nM/16 nM/14 nM and 3 nM for PI3Kα/β/γ/δ and mTOR, respectively. PKI-402 is a potent dual inhibitor of PI3K/mTOR with IC50 values of 2 nM/7 nM/16 nM/14 nM and 3 nM for PI3Kα/β/γ/δ...

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  • CZ415

    Biovision | CZ415 | B1726

    CZ415 is a potent and highly selective mTOR inhibitor.CZ415 is a potent and highly selective mTOR inhibitor.Biovision | B1726 | CZ415 DataSheetAlternate Name/Synonyms: CZ415; CZ 415; CZ-415;...

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  • Novobiocin Sodium Salt

    Biovision | Novobiocin Sodium Salt | B1526

    Novobiocin is a coumarin antibiotic isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the ATPase reaction catalyzed by the GyrB subunit. In addition to...

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  • Brivanib Alaninate

    Biovision | Brivanib Alaninate | B1326

    Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.Biovision...

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  • Azithromycin

    Biovision | Azithromycin | B1226

    Azithromycin is a macrolide antibiotic that inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram positive and negative bacteria. In vivo activity shows improved pharmacokinetic properties when compared to erythromycin...

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  • Trifluorothymidine

    Biovision | Trifluorothymidine | B1126

    Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR...

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  • PF-3274167

    Biovision | PF-3274167 | B1026

    PF-3274167 is a potent, selective, and high-affinity non-peptide oxytocin receptor (OTR) antagonist (Ki of 9.5 nM).PF-3274167 is a potent, selective, and high-affinity non-peptide oxytocin receptor (OTR) antagonist (Ki of 9.5 nM).Biovision | B1026 |...

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  • Raptinal

    Biovision | Raptinal | 9626

    Raptinal is a rapid inducer of apoptosis. Consistent with apoptotic morphological changes, U-937 cells treated with 10 μM Raptinal displays modest (at 30 min) and extensive (at 60 min) blebbing. Consistent with caspase-dependent apoptosis, the...

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  • Posaconazole

    Biovision | Posaconazole | 9526

    Posaconazole is a broad-spectrum, second-generation triazole compound that displays antifungal activity. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14α-demethylase enzyme (IC₅₀s range from 7-200 nM), which results in a...

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  • J147

    Biovision | J147 | 9426

    J 147 is a potent neuroprotective and neurotrophic compound that protects against neurotoxicity in cortical neurons in vitro (EC₅₀ = 25 - 200 nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. J 147 has been...

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  • CL-387785

    Biovision | CL-387785 | 2826

    CL-387785 is an irreversible inhibitor of EGF-stimulated autophosphorylation of tyrosine residues in the epidermal growth factor receptor (EGFR) in vivo (IC₅₀ = 250-490 pM) and blocks EGF-mediated growth.CL-387785 is an irreversible inhibitor of...

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  • DMXAA

    Biovision | DMXAA | 2804

    DMXAA acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon regulatory factor 3 signaling pathway in leukocytes,...

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  • SGI-1027

    Biovision | SGI-1027 | 2726

    SGI-1027 is a selective DNA methyltransferase (DNMT) inhibitor. Inhibits DNMT1, DNMT3A, and DNMT3B with IC₅₀ values of 6, 8, and 7.5 µM, respectively. Treatment of different cancer cell lines with SGI-1027 results in selective degradation of DNMT1 with...

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  • STA-21

    Biovision | STA-21 | 2626

    STA-21 is a natural antibiotic that acts as a selective STAT3 inhibitor. It inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 μM. It blocks the growth and survival of cancer cells that express...

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  • Hypericin

    Biovision | Hypericin | 2526

    Isolated from Hypericum perforatum, St. John’s Wort. Hypericin has been shown to display antiviral and antiretroviral activity. A potent and selective inhibitor of protein kinase C (IC₅₀ = 3.4 µM). Also known to inhibit Casein Kinase II (CKII), MAP...

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  • Phytosphingosine

    Biovision | Phytosphingosine | 2426

    Phytosphingosine is a phospholipid structurally similar to Sphingosine (Cat. No. 2425). The physiological roles of phytosphingosine are largely unknown. Phytosphingosine induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells, and...

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  • BML-278

    Biovision | BML-278 | 2379

    Cell-permeable. A structurally novel activator of SIRT1 (EC₅₀ = 1 µM). Displays selectivity over SIRT2 and 3 (EC₅₀ = 25 and 50 µM respectively).BML-278 is a structurally novel activator of SIRT1 (EC₅₀ = 1 µM).Biovision | 2379 | BML-278 DataSheetAlternate...

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  • Sulfo-NHS-LC-Biotin

    Biovision | Sulfo-NHS-LC-Biotin | 2326

    KEY FEATURES: • Amine-reactive; has a spacer with arm length of 22.4 Å which helps to minimize steric hindrance to biotin labeling • More water-soluble than the corresponding NHS compound without the sulfo group • Membrane-impermeable • Forms...

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  • IOX1

    Biovision | IOX1 | 2266

    Cell-permeable. A histone demethylase (HDM) JMJD nhibitor. Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC₅₀s = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 µM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad...

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  • Xanthohumol

    Biovision | Xanthohumol | 2258

    Cell-permeable. A bioactive flavonoid antioxidant found in the flowering hops plant. Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby...

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  • Temozolomide

    Biovision | Temozolomide | 2226

    A DNA methylating agent. A second-generation imidazotetrazine prodrug that undergoes spontaneous conversion under physiological conditions to the active alkylating agent MTIC (3-methyl-(triazen-1-yl)imidazole-4-carboxamide). Displays antitumor activity...

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  • Garcinol

    Biovision | Garcinol | 2088

    Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 µM) and PCAF (IC50 = 5 µM) both in vitro and in vivo. HAT activity-dependent chromatin...

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  • Piceatannol

    Biovision | Piceatannol | 2072

    A natural stilbene and an analogue of Resveratrol (Cat. No. 1758-100, 500). Besides antioxidative effects, piceatannol exhibits potential anticancer properties as shown by its ability to suppress proliferation of a wide variety of tumor cells, including...

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  • Sirtinol

    Biovision | Sirtinol | 2062

    Cell-permeable. A selective sirtuin deacetylase inhibitor with IC50 values of 38, 68 and 131 μM for SIRT2, Sir2p and SIRT1 respectively. Sirtinol has no effect on HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory...

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  • WST-8

    Biovision | WST-8 | 2049

    WST-8 is a next generation tetrazolium reagent that serves as a sensitive chromogenic indicator for NADH. It is reduced by NADH at neutral pHs in the presence of 1-methoxy PMS to produce the corresponding formazan dye that absorbs at 460 nM. Useful in...

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  • Vatalanib, Free Base

    Biovision | Vatalanib, Free Base | 2026

    Cell-permeable. An inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC₅₀ = 77 nM) and VEGFR-2 (FLK-1/KDR, IC₅₀ = 37 nM), with slightly higher potency against the latter. At higher concentrations, other tyrosine kinases are also inhibited,...

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  • Cardiogenol C hydrochloride

    Biovision | Cardiogenol C hydrochloride | 1926

    Cell-permeable. Induces differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes (EC₅₀ = 100 nM).Cardiogenol C hydrochloride induces differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes (EC₅₀ = 100 nM).Biovision | 1926...

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  • 5-Azacytidine

    Biovision | 5-Azacytidine | 1854

    A potent growth inhibitor and cytotoxic agent; a potent DNA methyltransferase inhibitor. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes. Also...

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  • Niclosamide

    Biovision | Niclosamide | 1826

    A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly...

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  • Resveratrol

    Biovision | Resveratrol | 1758

    A phytoalexin found in the skin of red grapes and as a constituent in red wine. Displays anti-inflammatory, and anti-tumor properties. Acts as an antioxidant and specific inihibitor of cyclooxygenase-1 (COX-1). Resveratrol activates Sirtuin (SIRT1) gene,...

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  • JK 184

    Biovision | JK 184 | 1726

    An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC₅₀ = 210 nM).JK 184 is an imidazopyridine derivative that acts as a...

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  • IBMX

    Biovision | IBMX | 1714

    Cell-permeable. A nonspecific phosphodiesterase inhibitor (IC₅₀ values are 13, 18, 19, 32 and 50 μM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively).IBMX is a nonspecific phosphodiesterase inhibitor (IC₅₀ values are 13, 18, 19, 32 and 50 μM for PDE4,...

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  • n-Octyl-β-D-glucopyranoside

    Biovision | n-Octyl-β-D-glucopyranoside | 1646

    A non-ionic detergent useful for solubilizing membrane-bound proteins in their native state. Has been shown to increase the resolution of proteins in 2D gels. Due to its high critical micelle concentration (20 -25 mM), it can be easily removed by...

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  • BEZ235 (NVP-BEZ235)

    Biovision | BEZ235 (NVP-BEZ235) | 1626

    Orally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition; BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and...

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  • Trichostatin A

    Biovision | Trichostatin A | 1606

    Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In...

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  • Apicidin

    Biovision | Apicidin | 1601

    A potent, cell permeable inhibitor of histone deacetylase (IC₅₀ = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC₅₀ = 50 – 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also...

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  • G418 Sulfate

    Biovision | G418 Sulfate | 1557

    Aminoglycoside antibiotic related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors...

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  • Tryptone

    Biovision | Tryptone | M1523

    BioVision’s Tryptone is a pancreatic digest of casein and is used as a nitrogen source in culture media. It is capable of supporting growth of fastidious and non-fastidious microorganisms. The non-detectable concentration of carbohydrates allows its use...

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  • Yeast Extract

    Biovision | Yeast Extract | M1522

    BioVision’s Yeast Extract is prepared from autolyzed yeast. It is used in preparing microbiological culture media. Yeast extract is the water soluble portion of autolyzed yeast. The autolysis is carefully controlled to preserve the naturally occurring...

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  • LB Lennox Broth

    Biovision | LB Lennox Broth | M1521

    BioVision’s Lennox LB Broth is used in molecular genetic studies. It is a nutritionally rich media for the growth and maintenance of cultures of recombinant strain of E. coli. The inclusion of casein peptone and yeast extract supplies essential growth...

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  • Teriffic Broth

    Biovision | Teriffic Broth | M1520

    BioVision’s Terrific Broth is used with glycerol in cultivating recombinant strains of E. coli. Terrific broth is a highly enriched medium for improving yield in plasmid bearing E. coli. Recombinant strains have an extended growth phase in this medium...

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  • LB Miller Broth

    Biovision | LB Miller Broth | M1519

    BioVision’s LB Miller Broth is used in molecular genetic studies, as well as maintaining and propagating E. coli in molecular and microbiology procedures. The inclusion of casein peptone and yeast extract provides essential growth factors for the...

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  • RNase A, Recombinant

    Biovision | RNase A, Recombinant | M1517

    RNase A is an endoribonuclease that specifically cleaves the single strand RNA at the phosphodiester bond between the 5’-ribose of a nucleotide and the 3’ OH phosphate group of an adjacent pyrimidine nucleotide. The highest activity is demonstrated with...

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  • Viral Transport Medium

    Biovision | Viral Transport Medium | M1515

    BioVision’s Viral Transport Medium is formulated for viral research and diagnostics. It is used for the collection, transport, maintenance and culture of virus. Its unique formulation is negative for microbial growth after 48 h at 37 °C. This medium can...

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  • T4 DNA ligase

    Biovision | T4 DNA ligase | M1514

    T4 DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5' phosphate and 3' hydroxyl termini in duplex DNA or RNA. This enzyme joins blunt-end and cohesive-end termini as well as repairs single-stranded nicks in duplex DNA and...

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