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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • 8-Azaadenosine

    Biovision | 8-Azaadenosine | B2572

    8-Azaadenosine is an ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells...

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  • AZ-304

    Biovision | AZ-304 | B2571

    AZ-304 is a potent, ATP-competitive dual BRAF kinase inhibitor that inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC₅₀s of 79 nM, 38 nM and 68 nM, respectively. In addition,...

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  • ARN-272

    Biovision | ARN-272 | B2570

    ARN-272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC₅₀ = 1.8 µM). It attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Displays analgesic effects...

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  • Atractylenolide I

    Biovision | Atractylenolide I | B2568

    Atractylenolide I is a sesquiterpene that displays diverse biological activities, including anti-inflammatory, anti-angiogenic, anti-tumor, and antidepressant properties. It inhibits LPS-induced...

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  • TTP-22

    Biovision | TTP-22 | B2565

    TTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these...

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  • BAY-8002

    Biovision | BAY-8002 | B2564

    BAY-8002 is a potent dual MCT1/2 (Monocarboxylate Transporter ½) inhibitor. Inhibits cellular SNARF-5 fluorescence change (IC₅₀ = 85 nM) in MCT1-expressing DLD-1 cells. Arrests growth and increases...

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  • V-9302

    Biovision | V-9302 | B2563

    V-9302 is a competitive antagonist of transmembrane glutamine flux, that selectively targets the amino acid transporter ASCT2 (SLC1A5). V-9302 inhibits ASCT2-mediated glutamine uptake (IC₅₀ = 9.6 µM)...

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  • iCRT14

    Biovision | iCRT14 | B2562

    iCRT14 is a potent potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC₅₀ = 40.3 nM). It inhibits the interaction between...

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  • Glumetinib

    Biovision | Glumetinib | B2561

    Glumetinib (SCC-244) is a potent and highly selective inhibitor of c-Met kinase (IC₅₀ = 0.42 nM). Glumetinib displays subnanomolar potency against c-Met kinase activity and high selectivity versus...

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  • GW-311616A

    Biovision | GW-311616A | B2559

    GW-311616 hydrochloride is a potent and selective intracellular neutrophil elastase (NE, α-1-proteinase) inhibitor. Inhibits human neutrophil elastase (HNE) and is selective over other human serine...

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  • AMG-510

    Biovision | AMG-510 | B2558

    AMG-510 is an orally available agent that targets the specific KRAS mutation, p.G12C, with potential antineoplastic activity. Upon oral administration, KRAS mutant-targeting AMG-510 selectively...

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  • Vesatolimod

    Biovision | Vesatolimod | B2555

    Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7) agonist which has been developed as an anti-hepatitis B virus (HBV) agent.Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7)...

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  • L-Propargylglycine

    Biovision | L-Propargylglycine | B2551

    L-Propargylglycine (PAG) is an inhibitor of cystathionine γ-lyase (CSE). Cystathionine γ-lyase catalyzes H2S synthesis and is a potential target for modulating H2S levels under pathophysiological...

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  • nor-NOHA acetate

    Biovision | nor-NOHA acetate | B2550

    nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more...

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  • PF-04620110

    Biovision | PF-04620110 | B2549

    PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) inhibitor with (IC₅₀ = 19 nM).PF-04620110 is a potent and selective Acyl-CoA:diacylglycerol acyltransferase-1...

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  • RU-521

    Biovision | RU-521 | B2547

    RU-521 (RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor (Kd = 36.2 nM). RU-521 is active and selective in cellular assays of cyclic GMP-AMP synthase-mediated signaling and...

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  • KKL-35

    Biovision | KKL-35 | B2546

    KKL-35 is a potent trans-translation inhibitor that displays broad-spectrum antibiotic activity. KKL-35 inhibits trans-translation, and subsequent cell growth in a broad spectrum of bacterial strains...

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  • LOXO-101 sulfate

    Biovision | LOXO-101 sulfate | B2545

    LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC₅₀s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other...

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  • Cysmethynil

    Biovision | Cysmethynil | B2544

    Cysmethynil is a potent, time-dependent inhibitor of Icmt (IC₅₀= <200 nM). It acts as a competitive inhibitor with respect to the isoprenylated cysteine substrate and a noncompetitive inhibitor with...

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  • CBR-5884

    Biovision | CBR-5884 | B2543

    CBR-5884 is a potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) (IC₅₀ = 33 μM) inhibiting serine synthesis from 3-phosphoglycerate in cells. CBR-5884 inhibits serine...

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  • SBI-115

    Biovision | SBI-115 | B2542

    SBI-115 is a potent TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.SBI-115 is a potent TGR5 (GPCR19) antagonist. SBI-115 decreases...

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  • CY-09

    Biovision | CY-09 | B2541

    CY-09 is a potent and specific NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation.CY-09 is a potent and...

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  • Glesatinib

    Biovision | Glesatinib | B2540

    Glesatinib is a potent multitargeted tyrosine kinase inhibitor. It binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte...

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  • Sitravatinib

    Biovision | Sitravatinib | B2539

    Sitravatinib (MGCD516; MG516) is a potent receptor tyrosine kinase (RTK) inhibitor with IC₅₀s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2,...

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  • Massonianoside B

    Biovision | Massonianoside B | B2537

    Massonianoside B (MA) is a structurally unique natural product inhibitor of DOT1L with an IC50 value of 399 nM. It displays high selectivity for DOT1L over other S-adenosylmethionine (SAM)-dependent...

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  • Fadrozole

    Biovision | Fadrozole | B2536

    Fadrozole is a potent, nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and...

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  • Cabotegravir

    Biovision | Cabotegravir | B2535

    Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity against a broad range of HIV subtypes.Cabotegravir is a long acting HIV-1 integrase inhibitor that displays activity...

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  • Balovaptan

    Biovision | Balovaptan | B2534

    Balovaptan is a potent and selective vasopressin-1 receptor antagonistBalovaptan is a potent and selective vasopressin-1 receptor antagonistBiovision | B2534 | Balovaptan DataSheetAlternate...

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  • GNE-272

    Biovision | GNE-272 | B2533

    GNE-272 is a potent and selective in vivo probe for the bromodomains of CBP/EP300 (IC₅₀ values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively). Displays marked antiproliferative effect...

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  • CP-424174

    Biovision | CP-424174 | B2531

    CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits...

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  • NLRP3i

    Biovision | NLRP3i | B2529

    NLRP3i is an intermediate in the glyburide synthesis that acts as a NLRP3 inflammasome inhibitor. It inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size...

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  • STF-083010

    Biovision | STF-083010 | B2528

    STF-083010 is a potent Ire1 inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. It blocks endogenous XBP1 mRNA...

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  • Ac-IEPD-AFC

    Biovision | Ac-IEPD-AFC | B2526

    Ac-IEPD-AFC is a useful fluorogenic substrate for the detection of Granzyme B. Granzyme B activity can be quantified by fluorescent detection of free AFC that has an excitation maximum at 400 nm and...

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  • LTURM-34

    Biovision | LTURM-34 | B2524

    LTURM-34 is a potent DNA-PK inhibitor (IC₅₀ = 34 nM). Displays 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro.LTURM-34 is a potent...

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  • PP121

    Biovision | PP121 | B2523

    PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 inhibits both tyrosine kinases and PI3-Ks but not serine-threonine kinases. It potently inhibits p110α, p110β, p110γ, p110δ,...

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  • NU-7026

    Biovision | NU-7026 | B2522

    NU-7026 is a potent DNA-PK inhibitor (IC₅₀ of 0.23 μM); displays 60-fold selectivity for DNA-PK than PI3K and inactive against both ATM and ATR.NU-7026 is a potent DNA-PK inhibitor (IC₅₀ of 0.23 μM);...

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  • AM-679

    Biovision | AM-679 | B2521

    AM-679 is a potent 5-lipoxygenase-activating protein (FLAP) inhibitor with IC₅₀s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.AM-679 is a potent 5-lipoxygenase-activating protein...

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  • MK-591, Free acid

    Biovision | MK-591, Free acid | B2520

    MK-0591 is a potent and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC₅₀ of 1.6 nM in FLAP binding assay; it displays no inhibitory effect on 15-lipoxygenase and platelet...

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