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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • (-)-Arctigenin

    Biovision | (-)-Arctigenin | B2786

    Arctigenin is a lignan found in the root of A. lappa. It displays antioxidant, anti-inflammatory, antiproliferative, and antiviral activity. At 0.1 μM, arctigenin can block the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1...

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  • MKC-8866

    Biovision | MKC-8866 | B2785

    MKC-8866 is a potent, and selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC-8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells...

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  • Desmosterol

    Biovision | Desmosterol | B2784

    Desmosterol is a C27 sterol intermediate in cholesterol synthesis generated during the metabolic pathway that transforms lanosterol into cholesterol. It may be associated with the pathogenesis of Alzheimer′s disease (AD). It has also been used to...

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  • Tetrahydropiperine

    Biovision | Tetrahydropiperine | B2782

    Tetrahydropiperine is a derivative of piperine (Cat. No. B2086) that displays various biological activities. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3 µM). It inhibits the cytochrome P450 (CYP) isoform...

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  • Tetrahydrocurcumin

    Biovision | Tetrahydrocurcumin | B2781

    Tetrahydrocurcumin (THC) is a major metabolite of curcumin that displays antioxidant and anti-inflammatory properties. It has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress. THC is...

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  • Sesamolin

    Biovision | Sesamolin | B2780

    Sesamolin is a furofuran lignan extracted from sesame seeds. It displays beneficial biological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. Also known to inhibit lipid peroxidation in rat liver and kidney...

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  • Montelukast sodium

    Biovision | Montelukast sodium | B2779

    Montelukast is a brain-penetrant cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor). It is selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes...

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  • Psoralen

    Biovision | Psoralen | B2778

    Psoralen belongs to the family of furanocoumarins that intercalates and induces interstrand cross-links in DNA. On UV exposure psoralen is excited leading to irreversible intercalation with DNA by covalent bond formation. This property of psoralen...

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  • Phyllanthin

    Biovision | Phyllanthin | B2777

    Phyllanthin is a major bioactive lignan found in many Phyllanthus species. It displays various biochemical and pharmacological properties especially on its hepatoprotective effects. It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM,...

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  • Lupeol

    Biovision | Lupeol | B2775

    Lupeol is a dietary triterpene that displays potent potent anti-inflammatory, anticarcinogenic, antimutagenic, and antimalarial activity. It suppresses the growth of hepatocellular carcinoma cell lines SMMC7721 and HepG2 with IC50 values of 45 and 48.5...

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  • Hibifolin

    Biovision | Hibifolin | B2774

    Hibifolin, a flavonol glycoside derived from herbal plants, displays strong protective activity against cell death induced by aggregated beta-amyloid (A beta). Hibifolin also acts as a potential inhibitor of adenosine deaminase (ADA).Hibifolin, a...

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  • (Z)-Guggulsterone

    Biovision | (Z)-Guggulsterone | B2773

    (Z)-Guggulsterone is a synthetic form of the guggul tree plant steroid that displays an ability to lower LDL cholesterol and triglyceride levels. Acts as a selective antagonist of farnesoid X receptor (FXR) and inhibits FXR transactivation (IC50 = 10 µM...

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  • Conessine

    Biovision | Conessine | B2772

    Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors. Conessine is 1860-fold selective for H3 over H4 and does not bind to H1 or H2 receptors. It also binds to the human α2C4 adrenergic receptor...

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  • Aloe-emodin

    Biovision | Aloe-emodin | B2771

    Aloe-emodin is a hydroxyanthraquinone found naturally in aloe plants. It displays antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. Acts as a laxative/cathartic compound; increases the contraction of intestinal smooth muscle by...

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  • Adenosine

    Biovision | Adenosine | B2770

    Adenosine is a purine nucleoside that serves as an endogenous ligand of a family of four adenosine receptors, which serve diverse roles related to smooth muscle tone, central nervous system regulation, and cardiac function. Adenosine is one of four...

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  • 12-Deoxywithastramonolide

    Biovision | 12-Deoxywithastramonolide | B2768

    12-Deoxywithastramonolide is a withanolide found in W. somnifera roots that displays anti-inflammatory activity, reducing TNF-α and increasing IL-10 production in mice 12-Deoxywithastramonolide also reduces the growth of A549 lung and HT-29 colorectal...

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  • Filastatin

    Biovision | Filastatin | B2767

    Filastatin is a nontoxic inhibitor of adhesion to human cells. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal...

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  • Etodolac

    Biovision | Etodolac | B2766

    Etodolac id a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2) (IC50 values are 53 and >100 μM for COX-2 and COX-1 respectively). Displays anti-inflammatory effects in both adjuvant arthritic and normal rats...

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  • CVT-10216

    Biovision | CVT-10216 | B2765

    CVT-10216 is a potent, selective, and reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats...

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  • BT2 (BCKDC Kinase Inhibitor)

    Biovision | BT2 (BCKDC Kinase Inhibitor) | B2764

    BT2 is an inhibitor of the mitochondrial branched-chain a-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM. Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 also acts as a...

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  • PF-04929113

    Biovision | PF-04929113 | B2763

    PF-04929113 is a prodrug for the Hsp90 inhibitor, PF-04958473 (SNX-2112). It binds both Hsp90α and Hsp90β with an IC50 value of 30 nM. PF-04929113, is rapidly absorbed and converted into the active inhibitor after oral administration. The active...

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  • YK-3-237

    Biovision | YK-3-237 | B2762

    YK-3-237 is a sirtuin 1(SIRT1) activator. It activates SIRT1 in a concentration-dependent manner and reduces acetylation of wild-type and mutant p53 in a SIRT1-dependent manner YK-3-237 inhibits cell growth in a panel of leukemia, non-small cell lung,...

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  • OSS-128167

    Biovision | OSS-128167 | B2761

    OSS-128167 is a potent and selective inhibitor of sirtuin 6 (SIRT6; IC50 = 89 μM). It displays selectivity for SIRT6 over SIRT1 and SIRT2 (IC50s = 1,578 and 751 μM, respectively). OSS-128167 increases acetylation of histone H3 lysine 9 (H3K9) and glucose...

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  • MDL-800

    Biovision | MDL-800 | B2760

    MDL-800 is a potent and selective allosteric activator (EC50 = 10.3 µM) of SIRT6, a member of the SIRT deacetylase family. Does not display any activities toward SIRT1, SIRT3, SIRT4 and HDAC1-11 at concentrations up to 50 μM or 100 μM. MDL-800 increases...

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  • UBCS-039

    Biovision | UBCS-039 | B2759

    UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.UBCS-039 is the...

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  • BMS-1001 free base

    Biovision | BMS-1001 free base | B2758

    BMS-1001 is a potent inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) (IC50 = 2.25 nM). BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of...

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  • PLpro inhibitor

    Biovision | PLpro inhibitor | B2757

    PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) (IC50 = 2.6 µM). PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 µM and an EC50 of 21.0 µM.PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) (IC50 = 2...

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  • Neoseptin-3

    Biovision | Neoseptin-3 | B2756

    Neoseptin-3 is a Toll-like receptor 4/myeloid differentiation factor 2 (mTLR4/MD-2) agonist (EC50 of 18.5 μM). Neoseptin-3 stimulates the activity of mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (mTLR) independently of CD14 (cluster of...

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  • JZL-184

    Biovision | JZL-184 | B2755

    JZL-184 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 8 nM and 4 µM for inhibition of MAGL and fatty acid amide hydrolase in mouse brain membranes, respectively. Monoacylglycerol lipase (MAGL) is a...

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  • 6877002

    Biovision | 6877002 | B2753

    6877002 is a CD40-TRAF6 interaction inhibitor compound that specifically targets TNF receptor-associated factor 6 (TRAF6; Kd = 97 µM for TRAF6 C-domain) and disrupts its functional coupling with CD40.6877002 is a CD40-TRAF6 interaction inhibitor compound...

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  • RMC-4550

    Biovision | RMC-4550 | B2752

    RMC-4550 is a potent, selective and allosteric inhibitor of SHP2 (IC50 = 0.583 nM). RMC-4550 inhibits the activity of full-length wild-type SHP2 enzyme activated by a di-phosphotyrosine peptide, but lacks activity against the free catalytic domain of...

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  • Dihomo-γ-Linolenic Acid

    Biovision | Dihomo-γ-Linolenic Acid | B2751

    Dihomo-γ-Linolenic Acid (DGLA, 20:3), an elongation product of γ-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series...

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  • BAY-1816032

    Biovision | BAY-1816032 | B2750

    BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM. Displays excellent selectivity over a panel of 395 kinases. BAY 1816032 abrogates nocodazole-induced Thr-120 phosphorylation...

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  • LLY-283

    Biovision | LLY-283 | B2749

    LLY-283 is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 = 22 nM). It is selective for PRMT5 over a panel of 32 methyltransferases, including PRMT4, -6, and -7 at 1 μM. LLY-283 reduces proliferation of various breast,...

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  • ASP-4132 tosylate

    Biovision | ASP-4132 tosylate | B2748

    ASP-4132 is a potent AMPK activator with potential antineoplastic activity. Upon oral administration, ASP4132 affects oxidative phosphorylation in mitochondria of metabolically-active tumor cells, which reduces both energy production and tumor cell...

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  • BSJ-03-123

    Biovision | BSJ-03-123 | B2747

    BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC). BSJ-03-123 causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.BSJ-03-123 is...

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  • SBI-797812

    Biovision | SBI-797812 | B2746

    SBI-797812 is a novel nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 acts as a “super catalyst” that more...

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  • GSK-3368715

    Biovision | GSK-3368715 | B2745

    GSK-3368715 is a potent, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). Displays anti-cancer...

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  • DiI Stain

    Biovision | DiI Stain | B2742

    DiI is a widely used lipophilic, carbocyanine membrane dye that labels cell membranes by inserting its two long (C18 carbon) hydrocarbon chains into the lipid bilayer. This dye is used primarily for optical recordings of membrane voltage and for studies...

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  • Sinomenine hydrochloride

    Biovision | Sinomenine hydrochloride | B2741

    Sinomenine is a natural plant alkaloid that displays anti-inflammatory properties. It activates histamine release, reduces joint stiffness and pain, and alters cytokine generation without producing gastrointestinal adverse events. Sinomenine also impairs...

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  • FB23-2

    Biovision | FB23-2 | B2740

    FB23-2 is a potent FTO (fat mass and obesity-associated) inhibitor. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity (IC50 = 2.6 µM). Mimicking FTO depletion, FB23-2 dramatically suppresses proliferation and promotes...

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  • IOX3 (FG-2216)

    Biovision | IOX3 (FG-2216) | B2739

    IOX3 (FG-2216) is a potent, orally bioavailable HIF-prolyl hydroxylase (PHD) inhibitor with IC50 of 3.9 µM for PDH2 enzyme. It has been shown to reversibly stimulate erythropoietin secretion at 100 µM in vitro.IOX3 (FG-2216) is a potent, orally...

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  • Meclofenamic acid sodium salt

    Biovision | Meclofenamic acid sodium salt | B2738

    Meclofenamic acid sodium is a non-steroidal, anti-inflammatory drug that acts as a time-dependent, non-specific competitive inhibitor of COX-1 and -2. Also acts as a highly selective fat mass and obesity-associated (FTO) inhibitor.Meclofenamic acid...

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  • Rhein

    Biovision | Rhein | B2737

    Rhein is an anthraquinone derivative that displays diverse biological activities, including anticancer, antioxidant, and anti-inflammatory activities. Also acts as a Fat mass and obesity-associated protein FTO (mRNA N6-methyladenine demethylase)...

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  • Bisantrene dihydrochloride

    Biovision | Bisantrene dihydrochloride | B2736

    Bisantrene dihydrochloride is the hydrochloride salt of an anthracenyl bishydrazone with antineoplastic activity. It intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition...

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  • Ketoconazole

    Biovision | Ketoconazole | B2735

    Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. Ketoconazole also inhibits...

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  • Vipadenant

    Biovision | Vipadenant | B2734

    Vipadenant is a selective adenosine receptor antagonist, with Kis of 1.3 nM and 68 nM for A2A and A1, respectively. Vipadenant also reverses haloperidol-induced hypolocomotion in mice and rats. Formulations containing vipadenant are under clinical...

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