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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • EZSolution™ Tandutinib

    Biovision | EZSolution™ Tandutinib | B2627

    A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ and c-Kit Tandutinib (Cat. No. 2024) in anhydrous DMSO.A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ and c-Kit Tandutinib (Cat. No. 2024) in anhydrous DMSO...

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  • EZSolution™ Crenolanib

    Biovision | EZSolution™ Crenolanib | B2626

    A 10 mM (5 mg in 1.13 ml) solution of the FLT3 tyrosine kinase inhibitor Crenolanib (Cat. No. 9679) in anhydrous DMSO.A 10 mM (5 mg in 1.13 ml) solution of the FLT3 tyrosine kinase inhibitor Crenolanib (Cat. No. 9679) in anhydrous DMSO.Biovision | B2626...

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  • EZSolution™ Saracatinib

    Biovision | EZSolution™ Saracatinib | B2625

    A 10 mM (5 mg in 922 µl) solution of the dual inhibitor of the tyrosine kinases c-Src and Abl Saracatinib (AZD-0530) (Cat. No. 1582) in anhydrous DMSO.A 10 mM (5 mg in 922 µl) solution of the dual inhibitor of the tyrosine kinases c-Src and Abl...

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  • EZSolution™ AZD-5438

    Biovision | EZSolution™ AZD-5438 | B2624

    A 10 mM (5 mg in 1.35 ml) of the CDK inhibitor AZD-5438 (Cat. No. B2073) in anhydrous DMSOA 10 mM (5 mg in 1.35 ml) of the CDK inhibitor AZD-5438 (Cat. No. B2073) in anhydrous DMSOBiovision | B2624 | EZSolution™ AZD-5438 DataSheetAlternate Name/Synonyms:...

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  • EZSolution™ Peficitinib

    Biovision | EZSolution™ Peficitinib | B2623

    A 10 mM (1 mg in 306 µl) of the JAK inhibitor Peficitinib (Cat. No. B2474) in anhydrous DMSOA 10 mM (1 mg in 306 µl) of the JAK inhibitor Peficitinib (Cat. No. B2474) in anhydrous DMSOBiovision | B2623 | EZSolution™ Peficitinib DataSheetAlternate...

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  • EZSolution™ PF-04965842

    Biovision | EZSolution™ PF-04965842 | B2622

    A 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOA 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOBiovision | B2622 | EZSolution™ PF-04965842 DataSheetAlternate...

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  • Sucralfate

    Biovision | Sucralfate | B2620

    Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by...

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  • Acetyl coenzyme A lithium salt

    Biovision | Acetyl coenzyme A lithium salt | B2619

    Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all...

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  • Qstatin

    Biovision | Qstatin | B2618

    Qstatin is a potent, and selective Vibrio QS inhibitor which affects Vibrio harveyi LuxR homologues, the well-conserved master transcriptional regulators for QS in Vibrio species. QStatin binds tightly to a putative ligand-binding pocket in SmcR, the...

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  • Paquinimod

    Biovision | Paquinimod | B2617

    Paquinimod is a small molecule quinoline-3-carboxamide derivative that acts as a S100A9 inhibitor. It targets the S100A9 protein and disrupts its binding to the pro-inflammatory receptors, Receptor for Advanced Glycation Endproducts (RAGE) and Toll-like...

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  • Astilbin

    Biovision | Astilbin | B2616

    Astilbin is a flavonoid that displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a...

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  • SR-144528

    Biovision | SR-144528 | B2615

    SR-144528 is a cannabinoid (CB) receptor 2 inverse agonist (Ki values ranging from 0.3 to 5.6 nM). Displays >700-fold selectivity for CB2 over CB1 receptors. Blocks the effects of CP-55,940 on forskolin-sensitive adenylyl cyclase activity and MAPK in CHO...

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  • MRTX-1257

    Biovision | MRTX-1257 | B2614

    MRTX-1257 is a potent, selective, and irreversible covalent inhibitor of KRAS G12C. MRTX-1257 inhibits KRAS dependent ERK-phosphorylation in the H358 cell with IC₅₀ of 0.9 nM. Displays high selectivity for the Cys12 of KRAS G12C in NCI-H358 cells over...

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  • URB597

    Biovision | URB597 | B2613

    URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). FAAH is the enzyme that hydrolyzes anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and...

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  • AEM1

    Biovision | AEM1 | B2611

    AEM1 is an inhibitor of Nrf2-induced gene transcription at the antioxidant response element in cells at 1 to 10 µM. It sensitizes lung carcinoma A549 cells to chemotherapeutic agents and inhibits the growth of A549 cells in vitro and in vivo in animals...

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  • Halofuginone hydrobromide

    Biovision | Halofuginone hydrobromide | B2610

    Halofuginone is an an ATP-dependent inhibitor prolyl-tRNA synthetase (Ki of 18.3 nM). Halofuginone attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Blocks expression of MMP2 and inhibits ECM invasion in vitro and lung metastasis by bladder...

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  • Chrysin

    Biovision | Chrysin | B2608

    Chrysin is a natural flavonoid that displays antioxidant, anti-inflammatory, and anticancer properties. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. In a mouse model of...

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  • Brusatol

    Biovision | Brusatol | B2607

    Brusatol is a quassinoid isolated from the Brucea javanica plant that has recently been shown to inhibit Nrf2 signaling, reduce tumor burden, and ameliorate chemoresistance in both in vitro and in vivo cancer models. Brusatol also inhibits c-Myc...

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  • Trigonelline Chloride

    Biovision | Trigonelline Chloride | B2606

    Trigonelline is a pyridine alkaloid found in various edible seeds and legumes, including coffee. It is a zwitterion formed by the methylation of the nitrogen atom of niacin (vitamin B3; nicotinic acid) and, as a product of niacin metabolism, is excreted...

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  • ML-385

    Biovision | ML-385 | B2605

    ML-385 is a potent and selective Nrf2 inhibitor (Nrf2; IC₅₀ = 1.9 µM). ML-385 blocks Nrf2 downstream target gene expression. ML-385 displays specificity and selectivity for NSCLC cells with KEAP1 mutation, which leads to gain of Nrf2 function.ML-385 is a...

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  • Cilofexor

    Biovision | Cilofexor | B2604

    Cilofexor (GS-9674), is a nonsteroidal bile acid farnesoid X receptor (FXR) agonist. It improves markers of cholestasis and liver injury in patients with PSC. PSC is an incurable rare chronic liver disease triggered by environmental, immunobiologic and...

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  • Tropifexor

    Biovision | Tropifexor | B2603

    Tropifexor (LJN452) is a highly potent, non-bile acid FXR (farnesoid X receptor) agonist with an EC₅₀ of 0.2 nM. Potentially useful for the treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).Tropifexor (LJN452) is a highly...

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  • BMS-779788

    Biovision | BMS-779788 | B2602

    BMS-779788 is a LXR partial agonist with IC₅₀ values of 68 nM for LXRα and 14 nM for LXRβ. BMS-779788 induces LXR target genes in blood in vivo with an EC₅₀ = 610 nM, a value similar to its in vitro blood gene induction potency.BMS-779788 is a LXR...

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  • A-485

    Biovision | A-485 | B2601

    A-485 is a potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor (IC₅₀ values are 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively). A-485 displays > 1000-fold selectivity over closely related...

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  • E7820

    Biovision | E7820 | B2600

    E7820 is a small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2...

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  • TCE35031

    Biovision | TCE35031 | B2599

    TCE35031 is an analog of Thalidomide (Cat. No. 2020) commonly used as a precursor to PROTACs (proteolysis-targeting chimera technologies) that hijack cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a...

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  • AZD-5904

    Biovision | AZD-5904 | B2598

    AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays similar potency in mouse and rat enzymes.AZD-5904 is a potent and irreversible inhibitor of human myeloperoxidase (MPO) (IC₅₀ = 140 nM). Displays...

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  • Succinobucol

    Biovision | Succinobucol | B2597

    Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. It displays anti-platelet activity in rabbit and rat blood and reverses the increase in platelet aggregation in response to oxidant stress. Potentially useful for the...

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  • Emricasan

    Biovision | Emricasan | B2596

    Emricasan (PF-03491390) is an irreversible pan-caspase inhibitor. In a mouse model of α-Fas-induced acute liver injury, the orally-administered caspase inhibitor Emricasan was retained in the liver for prolonged periods with a low systemic exposure...

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  • NS-11021

    Biovision | NS-11021 | B2595

    NS-11021 is a novel KCa1.1 channel activator. At concentrations above 0.3 μM, activates KCa1.1 in a concentration-dependent manner by parallel-shifting the channel activation curves to more negative potentials. Single-channel analysis reveals that...

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  • KIRA6

    Biovision | KIRA6 | B2594

    KIRA-6 is an ATP-competitive IRE1α kinase inhibiting RNase attenuator (KIRA) that allosterically inhibits IRE1α RNase kinase activity (IC₅₀ = 0.6 µM) and blocks oligomerization. It has been shown to inhibit IRE1α in vivo and to promote cell survival...

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  • PKM2 Inhibitor

    Biovision | PKM2 Inhibitor | B2593

    PKM2 inhibitor is a potent pyruvate kinase M2 (PKM2) inhibitor (IC₅₀ = 2.95 μM).PKM2 inhibitor is a potent pyruvate kinase M2 (PKM2) inhibitor (IC₅₀ = 2.95 μM).Biovision | B2593 | PKM2 Inhibitor DataSheetAlternate Name/Synonyms: MDK4882, PKM2...

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  • SAR-131675

    Biovision | SAR-131675 | B2592

    SAR-131675 is a potent and specific VEGFR-3 inhibitor. It inhibits VEGFR-3 tyrosine kinase activity (IC₅₀ = 20 nmol/L) and VEGFR-3 autophosphorylation (IC₅₀ = 5 nmol/L) in HEK cells, respectively. SAR-131675 is highly specific for VEGFR-3 versus 107...

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  • Methyl-β-cyclodextrin

    Biovision | Methyl-β-cyclodextrin | B2591

    Methyl-β-cyclodextrin is a randomly methylated form of β-cyclodextrin. Methyl-β-cyclodextrin has been used to improve the aqueous solubility of various compounds as well as to extract cholesterol from lipid membranes.Methyl-β-cyclodextrin is a randomly...

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  • O-Propargyl-puromycin

    Biovision | O-Propargyl-puromycin | B2590

    O-Propargyl-puromycin (OPP) is cell-permeable alkyne analog of the protein synthesis inhibitor puromycin (Cat. No. 1860) that efficiently incorporates into newly translated proteins in complete methionine-containing media. The resulting truncated...

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  • SB-297006

    Biovision | SB-297006 | B2589

    SB-297006 is a C-C chemokine receptor-3 antagonist (CCR3; IC₅₀ = 39 nM).SB-297006 is a C-C chemokine receptor-3 antagonist (CCR3; IC₅₀ = 39 nM).Biovision | B2589 | SB-297006 DataSheetAlternate Name/Synonyms: SB297006, SB 297006,...

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  • MX1013

    Biovision | MX1013 | B2588

    MX-1013, as a potent, irreversible dipeptide caspase inhibitor. It inhibits caspases 1, 3, 6, 7, 8, and 9, with IC₅₀ values ranging from 5 to 20 nm. MX1013 is selective for caspases, and is a poor inhibitor of non-caspase proteases, such as cathepsin B,...

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  • UNBS-5162

    Biovision | UNBS-5162 | B2587

    UNBS5162 is a novel naphthalimide that suppresses the expression of CXCL chemokines. In vitro exposure of PC-3 prostate cancer cells to 1 µM UNBS5162 for five successive days is shown to decrease the expression of proangiogenic CXCL chemokines. UNBS5162...

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  • PD-L1 Binding Peptide, WL12

    Biovision | PD-L1 Binding Peptide, WL12 | B2586

    WL12 peptide is a highly specific programmed death ligand 1 (PD-L1) binding peptide that can be used as a PET (positron emission tomography) imaging agent for PD-L1. PD-L1 is an immune checkpoint protein over-expressed in several cancers and contributes...

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  • N-Oleoylethanolamine

    Biovision | N-Oleoylethanolamine | B2585

    Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid Anandamide (N-arachidonoylethanolamine; AEA) found in brain tissue. OEA is an endogenous, potent agonist for PPARα, exhibiting an EC₅₀ value of 120 nM in a transactivation assay.Oleoyl...

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  • SKQ1 Bromide

    Biovision | SKQ1 Bromide | B2584

    SKQ1 bromide is a cell-permeable mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease,...

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  • Tolvaptan

    Biovision | Tolvaptan | B2583

    Tolvaptan is a selective, competitive arginine vasopressin V2 receptor antagonist (IC₅₀ = 3 nM for rat receptor) and a diuretic agent. It is selective for V2 over V1 receptors (IC₅₀ = 0.58 μM). Used to treat hyponatremia (low blood sodium levels)...

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  • Octreotide acetate

    Biovision | Octreotide acetate | B2582

    Octreotide is the acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than...

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  • Furamidine dihydrochloride

    Biovision | Furamidine dihydrochloride | B2581

    Furamidine dihydrochloride is a potent, selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor (IC₅₀ = 9.4 μM). Displays selectivity over PRMT5, PRMT6 and CARM1 (IC50 values are 166, 283 and >400 μM respectively). Inhibits...

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  • Liraglutide

    Biovision | Liraglutide | B2580

    Liraglutide is a highly potent, long-acting glucagon-like peptide 1 (GLP-1) receptor agonist (EC₅₀ = 61 pM). It increases cAMP accumulation in CHO cells expressing the human GLP-1 receptor. Inhibits food and water intake, causing lasting and reversible...

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  • 6-Bromoisatin

    Biovision | 6-Bromoisatin | B2579

    6-Bromoisatin (6Br) acts as a chemopreventive compound. 6Br was found to be an effective chemo-preventative compound when orally administered in a 14-week colorectal cancer model.6-Bromoisatin (6Br) acts as a chemopreventive compound. 6Br was found to be...

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  • Digitoxin

    Biovision | Digitoxin | B2578

    Digitoxin is a lipid soluble cardiac glycoside that acts as an inhibitor of plasma membrane Na+/K+-ATPase (EC₅₀ = 0.78 µM). Digitoxin shows a significantly cytotoxic effect in H1975 cells by causing G2 phase arrest.Digitoxin is a lipid soluble cardiac...

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  • Lanatoside C

    Biovision | Lanatoside C | B2577

    Lanatoside C is a cardiac glycoside, used in the treatment of congestive heart failure and cardiac arrhythmia. Lanatoside C suppresses colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing...

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  • BT-13

    Biovision | BT-13 | B2576

    BT-13 is a potent and selective agonist of RET tyrosine kinase and its downstream signaling cascades. BT-13 promotes neurite growth from sensory neurons in vitro and attenuates experimental neuropathy in the Rat.BT-13 is a potent and selective agonist of...

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  • MS023

    Biovision | MS023 | B2575

    MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) (IC₅₀s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively). MS023 is completely inactive against type II...

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  • Ataciguat

    Biovision | Ataciguat | B2574

    Ataciguat is an anthranilic acid derivative that activates the oxidized (heme-free) form of soluble guanylate cyclase (sGC) (EC₅₀= 0.5-10 µM in purified bovine lung or crude human corpus cavernosum isolates) by binding to the heme pocket and mimicking...

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